KCNK13 antibody

Principal name

KCNK13 antibody

Alternative names for KCNK13 antibody

KCNK13, Potassium channel subfamily K member 13, THIK-1, Tandem pore domain halothane-inhibited potassium channel 1

SwissProt ID

Q8R1P5 (Mouse), Q9ERS0 (Rat), Q9HB14 (Human)

Gene ID

56659 (KCNK13), 64120 (Kcnk13), 217826

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Eq (Equine), Por (Porcine), Bov (Bovine), Can (Canine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of KCNK13 antibody

K2P13.1 (also med Tandem Pore Domain Halotane Inhibited K+ channel, THIK -1or KCNK13) is a member of the 2-pore (2P) domain K+ channels family that at the moment includes 15 members. These channels show little time or voltage dependence and are considered to be â??leakâ? or â??backgroundâ? K+ channels, thereby generating background currents which help set the membrane resting potential and cell excitation.The K2P channels have a sigture topology that includes four transmembrane domains and two pore domains with intracellular N- and C termini. It has been proposed that the functiol channel unit is a dimer.K2P channels are regulated by diverse physical and chemical stimuli including temperature, pH, mechanical stretch, inhalation anesthetics, etc. but are insensitive to classical K+ channel blockers.The K2P13.1 channel is activated by arachidonic acid and inhibited by the volatile anesthetic halothane. The channel is relatively widely expressed in peripheral tissues such as kidney, heart, lung and liver but it is also expressed in brain.The physiological function of the K2P13.1 channel is not clear but an involvement in the physiological response to reduced oxygen levels (hypoxia) has been proposed.

General readings

Rajan S, Wischmeyer E, Karschin C, et al. THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels. J. Biol. Chem. 2001; 276:7302-11

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNK13 (Center) antibody

  Rabbit Polyclonal KCNK13 Antibody  
Western blot analysis of KCNK13 in rat brain tissue lysate with KCNK13 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNK13 antibody

  Rabbit polyclonal Anti-K2P13.1 (THIK-1) (extracellular)  
Western blot analysis of rat kidney membranes: 1. Anti-K2P13.1 (THIK-1) (extracellular) antibody , (1:200). 2. Anti-K2P13.1 (THIK-1) (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNK13 antibody

  Rabbit Polyclonal Anti-KCNK13 Antibody  
WB Suggested Anti-KCNK13 Antibody Titration: 0.12 ug/ml; ELISA Titer: 1:1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Eq, Hu, Por, Rt ICC/IF, P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCNK13 antibody

  Rabbit Polyclonal Anti-KCNK13 Antibody  
WB Suggested Anti-KCNK13 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNK13 antibody

  Rabbit Polyclonal Anti-KCNK13 Antibody  
Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Mouse lung tissue, Primary antibody: (KCNK13 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

KCNK13 - human gene knockout kit via CRISPR

KCNK13 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KCNK13 - human gene knockout kit via CRISPR

KCNK13 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KCNK13 - human gene knockout kit via CRISPR

KCNK13 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KCNK13 - human gene knockout kit via CRISPR

KCNK13 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kcnk13 - mouse gene knockout kit via CRISPR

Kcnk13 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Kcnk13 - mouse gene knockout kit via CRISPR

Kcnk13 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kcnk13 - mouse gene knockout kit via CRISPR

Kcnk13 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kcnk13 - mouse gene knockout kit via CRISPR

Kcnk13 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

KCNK13 overexpression lysate

KCNK13 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcnk13 (GFP-tagged) - Mouse potassium channel, subfamily K, member 13 (Kcnk13), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnk13 (GFP-tagged) - Mouse potassium channel, subfamily K, member 13 (Kcnk13), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcnk13 (GFP-tagged) - Mouse potassium channel, subfamily K, member 13 (Kcnk13), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnk13 (GFP-tagged) - Mouse potassium channel, subfamily K, member 13 (Kcnk13), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcnk13 (Myc-DDK-tagged) - Mouse potassium channel, subfamily K, member 13 (Kcnk13), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnk13 (Myc-DDK-tagged) - Mouse potassium channel, subfamily K, member 13 (Kcnk13), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kcnk13 (Myc-DDK-tagged) - Mouse potassium channel, subfamily K, member 13 (Kcnk13), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnk13 (Myc-DDK-tagged) - Mouse potassium channel, subfamily K, member 13 (Kcnk13), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kcnk13 (GFP-tagged ORF) - Rat potassium channel, subfamily K, member 13 (Kcnk13), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kcnk13 (GFP-tagged ORF) - Rat potassium channel, subfamily K, member 13 (Kcnk13), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

19 Item(s)

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