KCNK13 antibody

Principal name

KCNK13 antibody

Alternative names for KCNK13 antibody

KCNK13, Potassium channel subfamily K member 13, THIK-1, Tandem pore domain halothane-inhibited potassium channel 1

SwissProt ID

Q8R1P5 (Mouse), Q9ERS0 (Rat), Q9HB14 (Human)

Gene ID

56659 (KCNK13), 64120 (Kcnk13)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Eq (Equine), Por (Porcine), Bov (Bovine), Can (Canine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of KCNK13 antibody

K2P13.1 (also med Tandem Pore Domain Halotane Inhibited K+ channel, THIK -1or KCNK13) is a member of the 2-pore (2P) domain K+ channels family that at the moment includes 15 members. These channels show little time or voltage dependence and are considered to be â??leakâ? or â??backgroundâ? K+ channels, thereby generating background currents which help set the membrane resting potential and cell excitation.The K2P channels have a sigture topology that includes four transmembrane domains and two pore domains with intracellular N- and C termini. It has been proposed that the functiol channel unit is a dimer.K2P channels are regulated by diverse physical and chemical stimuli including temperature, pH, mechanical stretch, inhalation anesthetics, etc. but are insensitive to classical K+ channel blockers.The K2P13.1 channel is activated by arachidonic acid and inhibited by the volatile anesthetic halothane. The channel is relatively widely expressed in peripheral tissues such as kidney, heart, lung and liver but it is also expressed in brain.The physiological function of the K2P13.1 channel is not clear but an involvement in the physiological response to reduced oxygen levels (hypoxia) has been proposed.

General readings

Rajan S, Wischmeyer E, Karschin C, et al. THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels. J. Biol. Chem. 2001; 276:7302-11

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNK13 (Center) antibody

Western blot analysis of KCNK13 in rat brain tissue lysate with KCNK13 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNK13 antibody

Western blot analysis of rat kidney membranes: 1. Anti-K2P13.1 (THIK-1) (extracellular) antibody , (1:200). 2. Anti-K2P13.1 (THIK-1) (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNK13 antibody

WB Suggested Anti-KCNK13 Antibody Titration: 0.12 ug/ml; ELISA Titer: 1:1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Eq, Hu, Por, Rt ICC/IF, P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCNK13 antibody

WB Suggested Anti-KCNK13 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNK13 (Center) Control Peptide

Western blot analysis in rat brain tissue lysate with KCNK13 antibody Cat.-No. AP55537PU-N at 0.5 µg/ml in (A) the absence and (B) the presence of blocking peptide.
50 µg / €160.00
  Acris Antibodies GmbH

KCNK13 antibody

KCNK13 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

KCNK13 antibody

Human Brain; Rabbit Anti-Q9HB14 Antibody. Catalog Number: ARP35347. Paraffin Embedded Tissue: Human Brain. Cellular Data: Neural Cells. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X - See more at: http://www.avivasysbio.com/anti-kcnk13-antibody-c-terminal-region-arp35347-p050.html#sthash.wo6qTH90.dpuf; KCNK13 antibody - C-terminal region (ARP35347_P050) in Human Brain cells using Immunohistochemistry Rabbit Aff - Purified Hu, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

KCNK13 antibody

Human Jurkat; WB Suggested Anti-KCNK13 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:312500. Positive Control: Jurkat cell lysate; KCNK13 antibody - C-terminal region (ARP35348_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
0.1 mg / €310.00
  AVIVA Systems Biology

KCNK13 antibody

KCNK13 Rabbit Purified Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

KCNK13 antibody

KCNK13 Rabbit Purified Hu WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

KCNK13 overexpression lysate

KCNK13 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

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