KCNN1 antibody

Principal name

KCNN1 antibody

Alternative names for KCNN1 antibody

KCNN1, SK, SK1, Small conductance calcium-activated potassium channel protein 1

SwissProt ID

P70606 (Rat), Q92952 (Human), Q9EQR3 (Mouse)

Gene ID

3780 (KCNN1), 54261 (Kcnn1)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C), Paraffin Sections (P)

Background of KCNN1 antibody

KCa2.1 is a member of the Ca2+-activated K+ channels family with small conductance that includes KCa2.2 (SK2) and KCa2.3 (SK3). The channel is voltage insensitive and is activated by intracellular Ca2+ in the submicromolar range. It has a similar topology to that of voltage-dependent K+ channels (KV channels), that is six transmembrane domains and intracellular N- and C-termini. KCa2.1 channel expression is roughly confined to neurol tissue, although there are some indications that it may be present in non-neurol tissues as well. The sensitivity of KCa2.1 to the bee venom toxin Apamin is a matter of some controversy. Expression of the human KCa2.1 in mammalian cell lines showed that most cells produce channels that can be blocked by Apamin. However, expression of KCa2.1 in Xenopus oocytes produced channels that were mostly insensitive to apamin. Interestingly, the rat KCa2.1 is uble to form functiol channels when expressed alone in either cell lines or oocytes.

General readings

Arnold,S.J., et al., (2003) Neuroreport 14 (2), 191-195

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNN1 antibody

Western blot analysis of rat brain cortex: 1. Anti-KCa2.1 (SK1, SKCa1) antibody , (1:200). 2. Anti-KCa2.1 (SK1, SKCa1) antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNN1 antibody

WB Suggested Anti-KCNN1 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNN1 antibody

Human Jurkat; WB Suggested Anti-KCNN1 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:312500. Positive Control: Jurkat cell lysate; KCNN1 antibody - C-terminal region (ARP35095_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Hu WB
0.1 mg / €310.00
  AVIVA Systems Biology

KCNN1 antibody

KCNN1 Rabbit Hu C, P
0.1 ml / €400.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

KCNN1 overexpression lysate

KCNN1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

5 Item(s)

per page
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