KCNT1 antibody

Principal name

KCNT1 antibody

Alternative names for KCNT1 antibody

KIAA1422, KCa4.1, Potassium channel subfamily T member 1

SwissProt ID

Q5JUK3 (Human), Q6ZPR4 (Mouse), Q8QFV0 (Chick), Q9Z258 (Rat)

Gene ID

57582 (KCNT1), 60444 (Kcnt1), 227632

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of KCNT1 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
Slo2.2 is a novel member of the mammalian Slo potassium channel gene family. Slo2 channels may contribute to the resting potentials of cells that control their basal level of excitability (3). They also have sensors that couple channel activity to the intracellular concentrations of Na+ and Cl-(4).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCNT1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using KCNT1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

KCNT1 (1168-1237) antibody

Western blot analysis of Slo2.2 (SLACK) in rat brain membrane cell lysates using a 1:1000 dilution of the antibody Mouse IgG1 S3-26 Purified Ms, Rt C, ICC/IF, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCNT1 antibody

Western blot analysis of rat brain membrane: 1. Anti-KCa4.1 (Slack) antibody , (1:200). 2. Anti-KCa4.1 (Slack) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

KCNT1 antibody

WB Suggested Anti-Kcnt1 Antibody; Titration: 1.0 ug/ml; Positive Control: Mouse Heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

KCNT1 antibody

Immunoblot against brain membranes from adult rat (RBM) or from Slo2.2 knockout (MBM-Slo2.2 KO) or wild-type (MBM-WT) mice probed with N3/26 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Chris Lingle (Washington University). Mouse IgG1 N3/26 Supernatant Hu, Ms, Rt C, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

KCNT1 antibody

Immunoblot against brain membranes from adult rat (RBM) or from Slo2.2 knockout (MBM-Slo2.2 KO) or wild-type (MBM-WT) mice probed with N3/26 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Chris Lingle (Washington University). Mouse IgG1 N3/26 Purified Hu, Ms, Rt C, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

KCNT1 (C-term) antibody

Immunhistochemistry analysis in human brain/cortex (Cell processes) (Formalin-fixed, Paraffin-embedded) using KCNT1 antibody Cat.-No. AP32321PU-N. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

KCNT1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCNT1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €205.00
  Assay Biotech

KCNT1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCNT1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €310.00
  Assay Biotech

KCNT1 (C-term) antibody

Mouse Heart; WB Suggested Anti-Kcnt1 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Mouse Heart; Kcnt1 antibody - C-terminal region (ARP49576_P050) in Mouse Heart cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

KCNT1 antibody

KCNT1 Rabbit Serum Hu C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

KCNT1 antibody

Western Blot: KCNT1 Antibody (S3-26) [NBP1-44508] - Adult rat brain membrane probed with NBP1-44508. Mouse IgG1 S3-26 Purified Rt C, ICC/IF, P, WB
0.1 mg / €530.00
  Novus Biologicals Inc.

KCNT1 antibody

KCNT1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €360.00
  Novus Biologicals Inc.

KCNT1 antibody

KCNT1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
50 µg / €290.00
  Novus Biologicals Inc.

Lysates (Overexpressed)

Catalog No.    

KCNT1 overexpression lysate

KCNT1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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