KCP / CRIM2 antibody

Principal name

KCP / CRIM2 antibody

Alternative names for KCP / CRIM2 antibody

Kielin/chordin-like protein, KCP1, Cysteine-rich BMP regulator 2, Cysteine-rich motor neuron 2 protein, CRIM-2, Kielin/chordin-like protein 1, KCP-1

Gene ID

375616 (KCP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of KCP / CRIM2 antibody

CRIM2 Antibody: CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP sigling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-β1, suppressing activin- and TGF-β1-dependent transcription.

General readings

Lin J, Patel SR, Cheng X, et al. Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease. Nat. Med. 2005; 11:387-93

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCP / CRIM2 antibody

Western blot analysis of CRIM2 in Jurkat cell lysate with CRIM2 antibody at (A) 1 and (B) 2 µg/ml. Rabbit Purified Hu, Ms, Rt E, WB
0.1 mg / €345.00
  OriGene Technologies, Inc.

KCP / CRIM2 (C-term) antibody

Western blot analysis of CRIM2 in Jurkat cell lysate with CRIM2 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCP / CRIM2 (C-term) Control Peptide

KCP / CRIM2
50 µg / €160.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

KCP overexpression lysate

KCP overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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