KCTD11 antibody

Principal name

KCTD11 antibody

Alternative names for KCTD11 antibody

C17orf36, REN, BTB/POZ domain-containing protein KCTD11

SwissProt ID

Q58DF7 (Bovin), Q693B1 (Human), Q8K485 (Mouse)

Gene ID

147040 (KCTD11)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of KCTD11 antibody

The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling. Its inactivation might lead to a deregulation of the tumor promoting Hedgehog pathway in medulloblastoma. Plays a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1, thus maintaining cerebellar granule cells in undifferentiated state.

General readings

Gallo R., et al. (2002) J Cell Biol. 158:731-740.Di Marcotullio L., et al. (2004) Proc Natl Acad Sci USA. 101:10833-10838.

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KCTD11 antibody

HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human KCTD11 with DDK (FLAG) tag probed with TA311151 (1.0ug/ml) in Lane A and probed with anti-DDK Tag (1:5000, Cat# TA50011-100) in Lane C. Mock-transfected HEK293 probed with TA311151 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCTD11 antibody

WB Suggested Anti-KCTD11 Antibody Titration: 1.25 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCTD11 antibody

WB Suggested Anti-KCTD11 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KCTD11 antibody

Human Jurkat; WB Suggested Anti-KCTD11 Antibody Titration: 1.25ug/ml. Positive Control: Jurkat cell lysate; KCTD11 antibody - N-terminal region (ARP35623_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

KCTD11 antibody

Human 721_B; Host: Rabbit. Target Name: KCTD11. Sample Tissue: 721_B. Antibody Dilution: 1.0ug/ml.; KCTD11 antibody - N-terminal region (ARP36786_T100) in Human 721_B cells using Western Blot Rabbit Aff - Purified Hu WB
0.1 mg / €310.00
  AVIVA Systems Biology

KCTD11 antibody

KCTD11 Goat Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

KCTD11 antibody

KCTD11 Rabbit Purified Bov, Hu, Ms, Rt WB
0.1 mg / €360.00
  Novus Biologicals Inc.

KCTD11 antibody

KCTD11 Rabbit Purified Hu WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KCTD11

KCTD11 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

KCTD11 (1-232, His-tag)

KCTD11 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

KCTD11 (1-232, His-tag)

KCTD11 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

KCTD11 overexpression lysate

KCTD11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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