KDEL Receptor 1 / KDELR1 antibody

Principal name

KDEL Receptor 1 / KDELR1 antibody

Alternative names for KDEL Receptor 1 / KDELR1 antibody

KDEL endoplasmic reticulum protein retention receptor 1, ERD2.1, ER marker, ER lumen protein retaining receptor 1, Putative MAPK-activating protein PM23

SwissProt ID

P24390 (Human), P33946 (Bovin), Q569A6 (Rat), Q99JH8 (Mouse)

Gene ID

10945 (KDELR1), 618184, 68137 (Kdelr1)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Hst (Hamster), Hu (Human), Mky (Monkey), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Sh (Sheep), Xen (Xenopus), Av (Birds), Pl (Plant), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of KDEL Receptor 1 / KDELR1 antibody

The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). However, variation on KDEL does occur and other sequences can also give rise to endoplasmic reticulum retention (6). There are three KDEL receptors in mammalian cells, all have a very high degree of sequence identity; and all are located within the cis-Golgi and its intermediate compartments (4).
In terms of function, KDEL receptors interact with GAP (GTPase-activating protein) of ARF1, which is involved in COPI dependent vesicle transport, and the KDEL receptor may also be responsible for the recruitment of this ARF1 to membranes which can then aid in the regulation of vesicle budding (3). It is also important to note that the KDEL receptor exhibits extensive sequence identity o yeast protein Erd2p, which is a receptor for the yeast ER retention signal (4, 5).

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KDEL Receptor 1 / KDELR1 antibody

Western blot analysis of KDEL in rat tissue lysate, using a 1:1000 dilution of anti-KDELR1. Mouse IgG1 KR-10 Purified Bov, Can, Chk, Dros, Hst, Hu, Mky, Ms, Por, Rb, Rt, Sh, Xen C, ICC/IF, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KDEL Receptor 1 / KDELR1 antibody

Western blot analysis of KDEL in rat tissue lysate, using a 1:1000 dilution of anti-KDELR1. Mouse IgG1 KR-10 Purified Bov, Can, Chk, Dros, Hst, Hu, Mky, Ms, Por, Rb, Rt, Sh C, ICC/IF, IP, WB
25 µg / €230.00
  Acris Antibodies GmbH

KDEL Receptor 1 / KDELR1 (C-term) antibody

KDEL Receptor 1 / KDELR1 Mouse IgG2b 2E7 Purified Dros, Pl, Ye ICC/IF, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

KDEL Receptor 1 / KDELR1 (C-term) antibody

KDEL Receptor 1 / KDELR1 Mouse IgG2b 2E7 Purified Dros, Ye ICC/IF, WB
25 µg / €250.00
  Acris Antibodies GmbH

KDEL Receptor 1 / KDELR1 antibody

KDEL Receptor 1 / KDELR1 Mouse IgG1 KR-10 Av, Bov, Chk, Hst, Hu, Mky, Ms, Rt, Sh ICC/IF, IP, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KDEL Receptor 1 / KDELR1

KDEL Receptor 1 / KDELR1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

KDEL Receptor 1 / KDELR1

KDEL Receptor 1 / KDELR1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
2 µg / €290.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

KDELR1 overexpression lysate

KDELR1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

8 Item(s)

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