Kelch-like protein 13 antibody

Principal name

Kelch-like protein 13 antibody

Alternative names for Kelch-like protein 13 antibody

KLHL13, BKLHD2, KIAA1309, BTB and kelch domain-containing protein 2

SwissProt ID

Q80TF4 (Mouse), Q9P2N7 (Human)

Gene ID

90293 (KLHL13)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Frozen Sections (C)

Background of Kelch-like protein 13 antibody

KLHL13 (kelch-like 13), also known as BKLHD2 (BTB and kelch domain-containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate- specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Via its BTB and C-terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL-3 ligase.

General readings

Nagase T,. DNA Res. 2000 Feb 28;7(1):65-73.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Kelch-like protein 13 antibody

Immunohistochemical analysis of paraffin-embedded brain tissues (left) and pancreas tissues (right) using KLHL13 mouse mAb with DAB staining. Mouse IgG1 8D1 Ascites Hu E, F, ICC/IF, P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

Kelch-like protein 13 antibody

WB Suggested Anti-KLHL13 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Kelch-like protein 13 antibody

Human Intestine; KLHL13 antibody - N-terminal region (ARP34652_P050) in Human Intestine cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms P, WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Kelch-like protein 13

Kelch-like protein 13 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Kelch-like protein 13

Kelch-like protein 13 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

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