KIN antibody

Principal name

KIN antibody

Alternative names for KIN antibody

KIN, BTCD, KIN17, Binding to curved DNA, DNA/RNA-binding protein KIN17, KIN, antigenic determinant of recA protein homolog

SwissProt ID

O60870 (Human), Q55D16 (Dicdi), Q8K339 (Mouse), Q9Y7X9 (Schpo)

Gene ID

22944 (KIN)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E)

Background of KIN antibody

Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog.

General readings

"Differential expression of the HsKin17 protein during differentiation of in vitro reconstructed human skin."Biard D.S.F., Saintigny Y., Maratrat M., Vozenin M.-C., Martin M., Daburon F., Angulo J.F.Arch. Dermatol. Res. 289:448-456(1997)
"Human kin17 protein directly interacts with the simian virus 40 large T antigen and inhibits DNA replication." Miccoli L., Biard D.S.F., Creminon C., Angulo J.F. Cancer Res. 62:5425-5435(2002) "Selective interactions of human kin17 and RPA proteins with chromatin and the nuclear matrix in a DNA damage- and cell cycle-regulated manner." Miccoli L., Biard D.S.F., Frouin I., Harper F., Maga G., Angulo J.F. Nucleic Acids Res. 31:4162-4175(2003)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KIN antibody

WB Suggested Anti-KIN Antibody Titration: 2.5 ug/ml; Positive Control: Jurkat cell lysate Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KIN antibody

Human kidney; KIN antibody - middle region (AP42051PU-N) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu P, WB
50 µg / €350.00
  Acris Antibodies GmbH

KIN antibody

Human kidney; KIN antibody - middle region (ARP31690_P050) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu P, WB
50 µg / €350.00
  AVIVA Systems Biology

KIN antibody

Human Jurkat; WB Suggested Anti-KIN Antibody Titration: 2.5ug/ml. Positive Control: Jurkat cell lysate; KIN antibody - middle region (ARP32295_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KIN

KIN Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

KIN (1-393, His-tag)

KIN Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

KIN (1-393, His-tag)

KIN Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

KIN

KIN Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

KIN overexpression lysate

KIN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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