KIN antibody

Principal name

KIN antibody

Alternative names for KIN antibody

KIN, BTCD, KIN17, Binding to curved DNA, DNA/RNA-binding protein KIN17, KIN, antigenic determinant of recA protein homolog

SwissProt ID

O60870 (Human), Q55D16 (Dicdi), Q8K339 (Mouse), Q9Y7X9 (Schpo)

Gene ID

22944 (KIN), 16588 (Kin)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of KIN antibody

Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog.

General readings

"Differential expression of the HsKin17 protein during differentiation of in vitro reconstructed human skin."Biard D.S.F., Saintigny Y., Maratrat M., Vozenin M.-C., Martin M., Daburon F., Angulo J.F.Arch. Dermatol. Res. 289:448-456(1997)
"Human kin17 protein directly interacts with the simian virus 40 large T antigen and inhibits DNA replication." Miccoli L., Biard D.S.F., Creminon C., Angulo J.F. Cancer Res. 62:5425-5435(2002) "Selective interactions of human kin17 and RPA proteins with chromatin and the nuclear matrix in a DNA damage- and cell cycle-regulated manner." Miccoli L., Biard D.S.F., Frouin I., Harper F., Maga G., Angulo J.F. Nucleic Acids Res. 31:4162-4175(2003)

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KIN antibody

  Rabbit Polyclonal Anti-KIN Antibody  
WB Suggested Anti-KIN Antibody Titration: 2.5 ug/ml; Positive Control: Jurkat cell lysate Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

KIN - human gene knockout kit via CRISPR

KIN - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KIN - human gene knockout kit via CRISPR

KIN - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KIN - human gene knockout kit via CRISPR

KIN - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KIN - human gene knockout kit via CRISPR

KIN - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kin - mouse gene knockout kit via CRISPR

Kin - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Kin - mouse gene knockout kit via CRISPR

Kin - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kin - mouse gene knockout kit via CRISPR

Kin - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kin - mouse gene knockout kit via CRISPR

Kin - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KIN

  Recombinant protein of human KIN, antigenic determinant of recA protein homolog (mouse) (KIN)  
KIN Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

KIN (1-393, His-tag)

KIN Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

KIN (1-393, His-tag)

KIN Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

KIN overexpression lysate

KIN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KIN (mGFP-tagged) - Human KIN, antigenic determinant of recA protein homolog (mouse) (KIN), 200 uL, >10^7 TU/mL

Lenti ORF particles, KIN (mGFP-tagged) - Human KIN, antigenic determinant of recA protein homolog (mouse) (KIN), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kin (GFP-tagged) - Mouse antigenic determinant of rec-A protein (Kin), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kin (GFP-tagged) - Mouse antigenic determinant of rec-A protein (Kin), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kin (Myc-DDK-tagged) - Mouse antigenic determinant of rec-A protein (Kin), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kin (Myc-DDK-tagged) - Mouse antigenic determinant of rec-A protein (Kin), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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