Kininogen-1 antibody

Principal name

Kininogen-1 antibody

Alternative names for Kininogen-1 antibody

Fitzgerald factor, KNG1, BDK, KNG, High molecular weight kininogen, Williams-Fitzgerald-Flaujeac factor, Alpha-2-thiol proteinase inhibitor

SwissProt ID

O08677 (Mouse), P01042 (Human), P01044 (Bovin), P08934 (Rat)

Gene ID

3827 (KNG1), 16644 (Kng1), 25087 (Kng2)

Available reactivities

Hu (Human), Br (Broad), Ms (Mouse), Rt (Rat), Eq (Equine), Por (Porcine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Radioimmunoassay (R), Immunoprecipitation (IP), Immunodiffusion (ID), Flow Cytometry (F), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Kininogen-1 antibody

Bradykinin is a nine amino acid vasoactive peptide which elicits numerous physiologic responses such as vasodilation, smooth muscle spasm and pain. Bradykinin is one of a family of such peptides called the kinins. These kinins are generated by proteolysis of high molecular weight precursors called kininogens upon activation by pathophysiologic conditions such as inflammation or allergy. The physiological actions of these kinins are brought about through their interaction with transmembrane receptors. There are two distinct bradykinin receptor subtypes; B1 and B2, both of which appear to be coupled to G-proteins. The B2 receptor subtype is found in healthy smooth muscle cells and neurons, whereas the B1 receptors are only detected following tissue injury. The B2 receptor is similar in structure to other seven helix G protein coupled receptors. Bradykinin has relatively low affinity for B1 receptors, interacting primarily with the B2 receptor through which several second messenger systems are stimulated, including inositol phospholipid hydrolysis, arachidonic acid metabolism, tyrosine phosphorylation, and membrane depolarization and hyperpolarization.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)
Houlihan, L.M., et al. Am. J. Hum. Genet. 86(4):626-631(2010)
Khan, M.M., et al. Am. J. Physiol. Heart Circ. Physiol. 298 (2), H652-H658 (2010)
Bellucci, F., et al. Br. J. Pharmacol. 158(8):1996-2004(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Bradykinin (desArg9) antibody

Bradykinin Rabbit Purified Hu C, WB
50 µl / €490.00
  Acris Antibodies GmbH

Bradykinin antibody

Bradykinin Rabbit IgG Purified Br, Hu E
1 ml / €390.00
  Acris Antibodies GmbH

Kininogen-1 (N-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma reacted with Kininogen-1 Antibody (N-term) Cat.-No AP52400PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Kininogen-1 antibody

  Rabbit Polyclonal antibody to Kininogen 1 (kininogen 1)  
Sample (30 ug of whole cell lysate). A: Molt-4 . 10% SDS PAGE. TA308914 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Kininogen-1 antibody

  Rabbit polyclonal KNG1 (heavy chain, Cleaved-Lys380) antibody  
Western blot analysis of extracts from 293 cells, using KNG1 (heavy chain, Cleaved-Lys380) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Kininogen-1 antibody

  Anti-KNG1 Rabbit Polyclonal Antibody  
Predicted band size: 72 kDa . Positive control: Human plasma tissue lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Kininogen-1 antibody

  Goat Anti-kininogen 1 Antibody  
TA326302 (0.3µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Kininogen-1 (268-279) antibody

  Goat Anti-kininogen 1 (aa268-279) Antibody  
TA326721 (0.03µg/ml) staining of Albumin-depleted Plasma lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Kininogen-1 antibody

  Rabbit anti-KNG1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using KNG1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Kininogen-1 antibody

  Rabbit Polyclonal Anti-KNG1 Antibody  
WB Suggested Anti-KNG1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Liver Rabbit IgG Purified Eq, Hu, Ms, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

Kininogen-1 (LMW Isoform) antibody

Kininogen-1 Goat Serum Hu ID, IP
1 ml / €380.00
  Acris Antibodies GmbH

Kininogen-1 antibody

Kininogen-1 Goat Serum Hu ID, IP
1 ml / €380.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

KNG1 - human gene knockout kit via CRISPR

KNG1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KNG1 - human gene knockout kit via CRISPR

KNG1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kng1 - mouse gene knockout kit via CRISPR

Kng1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Kng1 - mouse gene knockout kit via CRISPR

Kng1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kng1 - mouse gene knockout kit via CRISPR

Kng1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kng1 - mouse gene knockout kit via CRISPR

Kng1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Bradykinin

Bradykinin Human Purified > 99 % pure prepared by Solid Phase synthesis.
1 mg / €180.00
  Acris Antibodies GmbH

Kininogen-1 (transcript variant 2)

  Recombinant protein of human kininogen 1 (KNG1), transcript variant 2  
Kininogen-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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