KIR3DL2 / CD158K antibody

Principal name

KIR3DL2 / CD158K antibody

Alternative names for KIR3DL2 / CD158K antibody

NKAT4, CD158 antigen-like family member K, MHC class I NK cell receptor, Natural killer-associated transcript 4, NKAT-4, p70 natural killer cell receptor clone CL-5, p70 NK receptor CL-5, Killer cell immunoglobulin-like receptor 3DL2

Gene ID

3812 (KIR3DL2)

Available reactivities

Hu (Human)

Available hosts


Available applications

Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E)

Background of KIR3DL2 / CD158K antibody

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by tural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory sigls upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kise binding protein to transduce activating sigls. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes.

General readings

Pende,D.,, J. Exp. Med. 184 (2), 505-518 (1996)
Dohring,C.,, Immunogenetics 44 (3), 227-230 (1996)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KIR3DL2 / CD158K antibody

KIR3DL2 / CD158K Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

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