KLF8 antibody

Principal name

KLF8 antibody

Alternative names for KLF8 antibody

KLF8, BKLF3, ZNF7, Krueppel-like factor 8, Basic krueppel-like factor 3, Zinc finger protein 741

SwissProt ID

O95600 (Human), Q8BLM0 (Mouse)

Gene ID

11279 (KLF8)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Can (Canine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of KLF8 antibody

KLF8 (Krueppel-like factor 8) is a protein that in humans is encoded by the KLF8 gene. It is also named as ZNF741, or BKLF3. Kruppel-like factor proteins, including KLF8, all contain a characteristic C-terminal DNA-binding domain containing 3 Kruppel-like zinc fingers, and they all recognize CACCC and GC boxes present in promoters and enhancers. The International Radiation Hybrid Mapping Consortium mapped the KLF8 gene to the X chromosome (WI-18614). Suske et al. (2005) stated that the human KLF8 gene maps to chromosome Xp11.21, and the mouse Klf8 gene to chromosome XF3. van Vliet et al. (2000) identified a cDNA encoding KLF8, also called ZNF741. Expression of KLF8 or only its zinc fingers showed that the fingers could bind to a CACCC box. Sequence analysis predicted that the 359-amino acid protein contains a nuclear localization signal upstream of the zinc fingers, a valine-rich hydrophobic stretch, and a pro-val-asp-leu-ser (PVDLS) motif. Yeast 2-hybrid and GST pull-down analysis demonstrated that CTBP2 interacts with KLF8 through the PVDLS motif.

General readings

van Vliet J, Turner J, Crossley M.
Human Kruppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription.
Nucleic Acids Res. 2000 May 1;28(9):1955-62.
PMID: 10756197

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KLF8 (N-term) antibody

  Goat Polyclonal Antibody against KLF8  
TA302802 staining (2µg/ml) of Human Kidney lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KLF8 antibody

  Rabbit Polyclonal Anti-KLF8 Antibody  
WB Suggested Anti-KLF8 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Can, GP, Hu, Ms, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

KLF8 antibody

  Rabbit Polyclonal Anti-KLF8 Antibody - N-terminal region  
WB Suggested Anti-KLF8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Placenta Rabbit IgG Purified GP, Hu, Ms, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

KLF8 - human gene knockout kit via CRISPR

KLF8 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KLF8 - human gene knockout kit via CRISPR

KLF8 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KLF8 - human gene knockout kit via CRISPR

KLF8 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KLF8 - human gene knockout kit via CRISPR

KLF8 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KLF8 (mGFP-tagged) - Human Kruppel-like factor 8 (KLF8), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, KLF8 (mGFP-tagged) - Human Kruppel-like factor 8 (KLF8), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, KLF8 (Myc-DDK tagged) - Human Kruppel-like factor 8 (KLF8), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, KLF8 (Myc-DDK tagged) - Human Kruppel-like factor 8 (KLF8), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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