KLK6 / Kallikrein-6 antibody

Principal name

KLK6 / Kallikrein-6 antibody

Alternative names for KLK6 / Kallikrein-6 antibody

Protease M, Neurosin, Zyme, SP59, Serine protease 9, Serine protease 18, PRSS18, PRSS9

SwissProt ID

P36374 (Rat), Q92876 (Human)

Gene ID

5653 (KLK6)

Available reactivities

Hu (Human), Can (Canine), Bov (Bovine), Ms (Mouse), Rt (Rat), Eq (Equine)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F)

Background of KLK6 / Kallikrein-6 antibody

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene that encodes KLK6 protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK6 is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human KLK6 with an internal ID of P04959

General readings

1. Anisowicz, A., Sotiropoulou, G., Stenman, G., Mok, S. C., Sager, R. A novel protease homolog
differentially expressed in breast and ovarian cancer. Molec. Med. 2: 624-636, 1996.
2. Elliott, M. B., Irwin, D. M., Diamandis, E. P. In silico identification and Bayesian phylogenetic
analysis of multiple new mammalian kallikrein gene families. Genomics 88: 591-599, 2006.
3. Iwata, A., Maruyama, M., Akagi, T., Hashikawa, T., Kanazawa, I., Tsuji, S., Nukina,
N. Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of
synucleinopathies.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KLK6 / Kallikrein-6 (C-term) antibody

TA305916 staining (2ug/ml) of Mouse Liver lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

Western Blot: KLK6 Antibody - Human salivary lysates. Rabbit Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

Western blot analysis of KLK6 (arrow) using rabbit polyclonal KLK6 Antibody (A13) (Cat. #TA324832). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the KLK6 gene. Rabbit IgG Purified Hu F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

Western blot analysis of KLK6 (arrow) using rabbit polyclonal KLK6 Antibody (L141) (Cat. #TA324833). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the KLK6 gene. Rabbit IgG Purified Hu F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

WB Suggested Anti-KLK6 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysate Rabbit IgG Purified Can, Eq, Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

ELISA: Kallikrein 6 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

Western Blot analysis of KLK6 expression in transfected 293T cell line by KLK6 monoclonal antibody (M01), clone 4A10.

Lane 1: KLK6 transfected lysate(26.9 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 4A10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

KLK6 / Kallikrein-6 antibody

Immunoblot analysis of cell lysates. Lane 1 : Bosc 23 cell lysate transfected with GFP. Lane 2 : Bosc 23 cell lysate transfected with myc/His-neurosin. Lane 3 : Bosc 23 cell lysate transfected with myc/His-Gpx3. Mouse IgG1 9A7 Hu WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

KLK6 / Kallikrein-6 antibody

KLK6 / Kallikrein-6 Rabbit Hu E
0.4 ml / €390.00
  Abnova Taiwan Corp.

KLK6 / Kallikrein-6 antibody

KLK6 / Kallikrein-6 Rabbit Hu E
0.4 ml / €390.00
  Abnova Taiwan Corp.

KLK6 / Kallikrein-6 antibody

Human Lung; Lung; KLK6 antibody - N-terminal region (ARP33888_P050) in Human Lung cells using Immunohistochemistry Rabbit Aff - Purified Can, Hu WB
50 µg / €350.00
  AVIVA Systems Biology

KLK6 / Kallikrein-6 antibody

KLK6 / Kallikrein-6 Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

KLK6 / Kallikrein-6 antibody

Kallikrein 6 satining paraffin embedded of breast cancer tissue sections Tissues were stained using anti-goat HRPDAB (brown) and counter-stained with hematoxylin (blue). Goat Aff - Purified Hu E, WB
0.1 mg / €450.00
  Neuromics Antibodies

KLK6 / Kallikrein-6 antibody

ELISA: Kallikrein 6 Antibody [33510002] Rabbit Hu E, WB
50 µg / €470.00
  Novus Biologicals Inc.

KLK6 / Kallikrein-6 antibody

KLK6 / Kallikrein-6 Rabbit Serum Hu WB
25 µl / €160.00
  Novus Biologicals Inc.

KLK6 / Kallikrein-6 antibody

KLK6 / Kallikrein-6 Goat Aff - Purified Bov, Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

KLK6 / Kallikrein-6 antibody

Western Blot: Kallikrein 6 Antibody [NBP1-54713] - This Anti-KLK6 antibody was used in Western Blot of 721_B tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu P, WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KLK6 / Kallikrein-6 (transcript variant B)

KLK6 / Kallikrein-6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 (transcript variant A)

KLK6 / Kallikrein-6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 (transcript variant C)

KLK6 / Kallikrein-6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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