KLK6 / Kallikrein-6 antibody

Principal name

KLK6 / Kallikrein-6 antibody

Alternative names for KLK6 / Kallikrein-6 antibody

Protease M, Neurosin, Zyme, SP59, Serine protease 9, Serine protease 18, PRSS18, PRSS9

SwissProt ID

P36374 (Rat), Q92876 (Human)

Gene ID

5653 (KLK6), 292866 (Klk1c8)

Available reactivities

Hu (Human), Can (Canine), Bov (Bovine), Ms (Mouse), Rt (Rat), Eq (Equine)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of KLK6 / Kallikrein-6 antibody

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene that encodes KLK6 protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK6 is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human KLK6 with an internal ID of P04959

General readings

1. Anisowicz, A., Sotiropoulou, G., Stenman, G., Mok, S. C., Sager, R. A novel protease homolog
differentially expressed in breast and ovarian cancer. Molec. Med. 2: 624-636, 1996.
2. Elliott, M. B., Irwin, D. M., Diamandis, E. P. In silico identification and Bayesian phylogenetic
analysis of multiple new mammalian kallikrein gene families. Genomics 88: 591-599, 2006.
3. Iwata, A., Maruyama, M., Akagi, T., Hashikawa, T., Kanazawa, I., Tsuji, S., Nukina,
N. Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of
synucleinopathies.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KLK6 / Kallikrein-6 (C-term) antibody

  Goat Anti-Klk6 / neurosin (mouse) Antibody  
TA305916 staining (2ug/ml) of Mouse Liver lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

  Rabbit Polyclonal Kallikrein 6 Antibody  
Western Blot: KLK6 Antibody - Human salivary lysates. Rabbit Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

  Rabbit polyclonal Kallikrein 6 Antibody (N-term)  
Western blot analysis of KLK6 (arrow) using rabbit polyclonal KLK6 Antibody (A13) (Cat. #TA324832). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the KLK6 gene. Rabbit IgG Purified Hu F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

  Rabbit polyclonal Kallikrein 6 Antibody (Center)  
Western blot analysis of KLK6 (arrow) using rabbit polyclonal KLK6 Antibody (L141) (Cat. #TA324833). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the KLK6 gene. Rabbit IgG Purified Hu F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

  Rabbit Polyclonal Anti-KLK6 Antibody  
WB Suggested Anti-KLK6 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysate Rabbit IgG Purified Can, Eq, Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

  Rabbit Polyclonal Anti-KLK6 Antibody  
Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: A375 cells, Primary antibody: (KLK6 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

  Rabbit Polyclonal Kallikrein 6 Antibody  
ELISA: Kallikrein 6 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 antibody

Kallikrein 6 satining paraffin embedded of breast cancer tissue sections Tissues were stained using anti-goat HRPDAB (brown) and counter-stained with hematoxylin (blue). Goat Aff - Purified Hu E, WB
0.1 mg / €450.00
  Neuromics Antibodies

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KLK6 / Kallikrein-6 (transcript variant B)

  Purified recombinant protein of Homo sapiens kallikrein-related peptidase 6 (KLK6), transcript variant B  
KLK6 / Kallikrein-6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 (transcript variant A)

  Recombinant protein of human kallikrein-related peptidase 6 (KLK6), transcript variant A  
KLK6 / Kallikrein-6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 (transcript variant C)

  Purified recombinant protein of Homo sapiens kallikrein-related peptidase 6 (KLK6), transcript variant C  
KLK6 / Kallikrein-6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

KLK6 / Kallikrein-6 (transcript variant B)

  Recombinant protein of human kallikrein-related peptidase 6 (KLK6), transcript variant B  
KLK6 / Kallikrein-6 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €399.00
  OriGene Technologies, Inc.

ELISA Kits

Catalog No.    

Human Kallikrein-6 ELISA Kit

Human Kallikrein-6 ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

KLK6 overexpression lysate

KLK6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

KLK6 overexpression lysate

KLK6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KLK6 (mGFP-tagged) - Human kallikrein-related peptidase 6 (KLK6), transcript variant A, 200 uL, >10^7 TU/mL

Lenti ORF particles, KLK6 (mGFP-tagged) - Human kallikrein-related peptidase 6 (KLK6), transcript variant A, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, KLK6 (mGFP-tagged) - Human kallikrein-related peptidase 6 (KLK6), transcript variant C, 200 uL, >10^7 TU/mL

Lenti ORF particles, KLK6 (mGFP-tagged) - Human kallikrein-related peptidase 6 (KLK6), transcript variant C, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, KLK6 (Myc-DDK tagged) - Human kallikrein-related peptidase 6 (KLK6), transcript variant B , 200 uL, >10^7 TU/mL

Lenti ORF particles, KLK6 (Myc-DDK tagged) - Human kallikrein-related peptidase 6 (KLK6), transcript variant B , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Lenti ORF particles, KLK6 (Myc-DDK tagged) - Human kallikrein-related peptidase 6 (KLK6), transcript variant C , 200 uL, >10^7 TU/mL

Lenti ORF particles, KLK6 (Myc-DDK tagged) - Human kallikrein-related peptidase 6 (KLK6), transcript variant C , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Klk1c8 (GFP-tagged ORF) - Rat kallikrein 1-related peptidase b21 (Klk1b21), 200 uL, >10^7 TU/mL

Lenti ORF particles, Klk1c8 (GFP-tagged ORF) - Rat kallikrein 1-related peptidase b21 (Klk1b21), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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