KLK7 / Kallikrein-7 antibody

Principal name

KLK7 / Kallikrein-7 antibody

Alternative names for KLK7 / Kallikrein-7 antibody

PRSS6, SCCE, Serine protease 6, hK7, Stratum corneum chymotryptic enzyme

SwissProt ID

P36373 (Rat), P49862 (Human), Q91VE3 (Mouse)

Gene ID

5650 (KLK7), 23993 (Klk7), 24523 (Klk1c7)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of KLK7 / Kallikrein-7 antibody

This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation; the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis; and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Altertively spliced transcript variants encoding multiple isoforms have been observed for this gene; which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.

General readings

Talieri,M.,et al. (2011) Anticancer Res. 31 (9), 3093-3100Ramani,V.C., et al. (2011) Biochim. Biophys. Acta 1813 (8), 1525-1531

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KLK7 / Kallikrein-7 antibody

  Anti-KLK7 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human colon and ovarian cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using KLK7 antibody at dilution 1/10, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

KLK7 / Kallikrein-7 antibody

  Anti-KLK7 Rabbit Polyclonal Antibody  
Predicted band size: 28 kDa . Positive control: Mouse brain and kidney tissue lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lane1: Mouse brain tissue lysate Lane2: Mouse kidney tissue lysate Lysates: 40 ug per lane Primary antibody: 1/600dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

KLK7 / Kallikrein-7 antibody

  Rabbit Polyclonal Anti-KLK7 Antibody - middle region  
Host: Rabbit; Target Name: KLK7; Sample Tissue: Fetal Brain lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

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