KPNA3 / Importin alpha-3 antibody

Principal name

KPNA3 / Importin alpha-3 antibody

Alternative names for KPNA3 / Importin alpha-3 antibody

Karyopherin subunit alpha-3, SRP1-gamma, Importin alpha Q2, QIP2

SwissProt ID

O00505 (Human), O35344 (Mouse)

Gene ID

3839 (KPNA3), 16648 (Kpna3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Hst (Hamster), Mky (Monkey), Por (Porcine), Prim (Primate), Rb (Rabbit), Xen (Xenopus), Tr (Turkey), L (Lizard), Bear, Ze (Zebrafish), African clawed frog, GP (Guinea Pig)

Available hosts

Mouse, Goat, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of KPNA3 / Importin alpha-3 antibody

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3 is a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggest that karyopherin alpha-3 may be involved in the nuclear transport system.The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3, encodes a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Singh,A.P., (2007) Cell 131 (3), 492-504

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KPNA3 / Importin alpha-3 (C-term) antibody

  Goat Polyclonal Antibody against KPNA3 / IPOA4  
TA302524 staining (0.1µg/ml) of Human Testis lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, ICC/IF, IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KPNA3 / Importin alpha-3 (C-term) antibody

  Rabbit Polyclonal KPNA3 Antibody  
Western blot analysis of KPNA3 in EL4 cell lysate with KPNA3 antibody at (A) 1 and (B) 2 µg/mL. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KPNA3 / Importin alpha-3 antibody

  Rabbit Polyclonal Anti-KPNA3 Antibody  
WB Suggested Anti-KPNA3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: MCF7 cell lysate.KPNA3 is strongly supported by BioGPS gene expression data to be expressed in MCF7 Rabbit IgG Purified Bov, GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

KPNA3 / Importin alpha-3 antibody

Human Hela; Host:Rabbit. Target Name:KPNA3. Sample Tissue:Hela. Antibody Dilution: 1.0ug/ml. KPNA3 is supported by BioGPS gene expression data to be expressed in HeLa.; KPNA3 antibody - N-terminal region (ARP54674_P050) in Human Hela cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

KPNA3 / Importin alpha-3 (alpha) antibody

Western blot analysis of Importin α3 expression in Jurkat cells (1), HeLa cells (2), Raji cells (3), HL60 cells (4), A431 cells (5), L5178Y cells (6), WR19L cells (7), NIH/3T3 cells (8), CHO cells (9), PC12 cells (10) and Rat 1 cells (11) using AM26501AF-N. Rat IgG2a 3D10 Azide Free Hst, Hu, Ms, Rt WB
0.1 mg / €400.00
  Acris Antibodies GmbH

KPNA3 / Importin alpha-3 (509-521) antibody

Heart: Fromalin-Fixed Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, L, Mky, Ms, Platypus, Por, Prim, Rb, Rt, Tr, Xen E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

KPNA3 / Importin alpha-3 (C-term) antibody

Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

KPNA3 / Importin alpha-3 antibody

KPNA3 polyclonal antibody (A01), Lot # FAK0060120QCS1 Western Blot analysis of KPNA3 expression in IMR-32 ( Cat # L008V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

KPNA3 / Importin alpha-3 antibody

KPNA3 polyclonal antibody ( Cat # PAB6560 ) staining ( 0.1 µg/ml ) of human testis lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CRISPR

Catalog No. Species Donor Vector  

KPNA3 - human gene knockout kit via CRISPR

KPNA3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KPNA3 - human gene knockout kit via CRISPR

KPNA3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KPNA3 - human gene knockout kit via CRISPR

KPNA3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KPNA3 - human gene knockout kit via CRISPR

KPNA3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kpna3 - mouse gene knockout kit via CRISPR

Kpna3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Kpna3 - mouse gene knockout kit via CRISPR

Kpna3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kpna3 - mouse gene knockout kit via CRISPR

Kpna3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kpna3 - mouse gene knockout kit via CRISPR

Kpna3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KPNA3 / Importin alpha-3

  Recombinant protein of human karyopherin alpha 3 (importin alpha 4) (KPNA3)  
KPNA3 / Importin alpha-3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

KPNA3 / Importin alpha-3

KPNA3 / Importin alpha-3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

KPNA3 / Importin alpha-3

KPNA3 / Importin alpha-3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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