KPNA3 / Importin alpha-3 antibody

Principal name

KPNA3 / Importin alpha-3 antibody

Alternative names for KPNA3 / Importin alpha-3 antibody

Karyopherin subunit alpha-3, SRP1-gamma, Importin alpha Q2, QIP2

SwissProt ID

O00505 (Human), O35344 (Mouse)

Gene ID

3839 (KPNA3), 16648 (Kpna3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Hst (Hamster), Mky (Monkey), Por (Porcine), Prim (Primate), Rb (Rabbit), Xen (Xenopus), Tr (Turkey), L (Lizard), Bear, Ze (Zebrafish), African clawed frog, GP (Guinea Pig)

Available hosts

Mouse, Goat, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of KPNA3 / Importin alpha-3 antibody

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3 is a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggest that karyopherin alpha-3 may be involved in the nuclear transport system.The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3, encodes a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Singh,A.P., (2007) Cell 131 (3), 492-504

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KPNA3 / Importin alpha-3 (C-term) antibody

  Goat Polyclonal Antibody against KPNA3 / IPOA4  
TA302524 staining (0.1µg/ml) of Human Testis lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, ICC/IF, IP, P, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

KPNA3 / Importin alpha-3 (509-521) antibody

Heart: Fromalin-Fixed Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Platypus, Por, Rb, Rt E, P, WB
50 µg / €380.00
  OriGene Technologies GmbH

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