KPNA6 / Importin alpha-7 antibody

Principal name

KPNA6 / Importin alpha-7 antibody

Alternative names for KPNA6 / Importin alpha-7 antibody

Karyopherin subunit alpha-6, KPNA6, IPOA7

SwissProt ID

O35345 (Mouse), O60684 (Human), Q0V7M0 (Bovin)

Gene ID

23633 (KPNA6), 16650 (Kpna6)

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog, Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of KPNA6 / Importin alpha-7 antibody

The import of proteins containing a nuclear localization sigl (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. KP6 is a member of the importin alpha family.Nucleocytoplasmic transport, a sigl- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization sigl (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

Ma J, Cao X. Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements. Cell Signal. 2006 Aug;18(8):1117-26. Epub 2005 Nov 18. PMID: 16298512

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

KPNA6 / Importin alpha-7 antibody

  Goat Anti-KPNA6 Antibody  
TA305673 (0.1ug/ml) staining of Human Muscle lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KPNA6 / Importin alpha-7 (N-term) antibody

  Rabbit Polyclonal KPNA6 Antibody  
Western blot analysis of KPNA6 in 293 cell lysate with KPNA6 antibody at 1 ug/mL. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

KPNA6 / Importin alpha-7 antibody

  Rabbit Polyclonal Anti-KPNA6 Antibody  
WB Suggested Anti-KPNA6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

KPNA6 - human gene knockout kit via CRISPR

KPNA6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

KPNA6 - human gene knockout kit via CRISPR

KPNA6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

KPNA6 - human gene knockout kit via CRISPR

KPNA6 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

KPNA6 - human gene knockout kit via CRISPR

KPNA6 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kpna6 - mouse gene knockout kit via CRISPR

Kpna6 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Kpna6 - mouse gene knockout kit via CRISPR

Kpna6 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

KPNA6 / Importin alpha-7

  Recombinant protein of human karyopherin alpha 6 (importin alpha 7) (KPNA6)  
KPNA6 / Importin alpha-7 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KPNA6 (mGFP-tagged) - Human karyopherin alpha 6 (importin alpha 7) (KPNA6), 200 uL, >10^7 TU/mL

Lenti ORF particles, KPNA6 (mGFP-tagged) - Human karyopherin alpha 6 (importin alpha 7) (KPNA6), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, KPNA6 (Myc-DDK tagged) - Human karyopherin alpha 6 (importin alpha 7) (KPNA6) , 200 uL, >10^7 TU/mL

Lenti ORF particles, KPNA6 (Myc-DDK tagged) - Human karyopherin alpha 6 (importin alpha 7) (KPNA6) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Kpna6 (GFP-tagged) - Mouse karyopherin (importin) alpha 6 (Kpna6), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kpna6 (GFP-tagged) - Mouse karyopherin (importin) alpha 6 (Kpna6), 200 uL, >10^7 TU/mL  
200 µl / €1,160.00
  OriGene Technologies, Inc.

Lenti ORF particles, Kpna6 (Myc-DDK-tagged) - Mouse karyopherin (importin) alpha 6 (Kpna6), 200 uL, >10^7 TU/mL

Lenti ORF particles, Kpna6 (Myc-DDK-tagged) - Mouse karyopherin (importin) alpha 6 (Kpna6), 200 uL, >10^7 TU/mL  
200 µl / €1,040.00
  OriGene Technologies, Inc.

14 Item(s)

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