L-xylulose reductase antibody

Principal name

L-xylulose reductase antibody

Alternative names for L-xylulose reductase antibody

XR, DCXR, Carbonyl reductase II, P34H, Dicarbonyl/L-xylulose reductase, Kidney dicarbonyl reductase, Sperm surface protein P34H

SwissProt ID

Q1JP75 (Bovin), Q7Z4W1 (Human), Q91X52 (Mouse), Q920P0 (Rat)

Gene ID

51181 (DCXR), 67880 (Dcxr), 171408

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Ze (Zebrafish)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F), EPair for Elisa (EPair), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of L-xylulose reductase antibody

DCXR is an enzyme that has both diacetyl reductase and L-xylulose reductase activities. 
Function: Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Cellular Location: Membrane; Peripheral membrane protein (By similarity). Note=Probably recruited to membranes via an interaction with phosphatidylinositol (By similarity).
Tissue Location: Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.

General readings

1. Nakagawa J, Ishikura S, Asami J, Isaji T, Usami N, Hara A, Sakurai T, Tsuritani K, Oda K, Takahashi M, Yoshimoto M, Otsuka N, Kitamura K.
Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney
J Biol Chem. 2002 May 17;277(20):17883-91
PMID: 11882650

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

L-xylulose reductase antibody

  anti-DCXR mouse monoclonal antibody, clone OTI7D11 (formerly 7D11)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-DCXR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500773, Dilution 1:50) Mouse IgG1 OTI7D11 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

L-xylulose reductase antibody

  anti-DCXR mouse monoclonal antibody, clone OTI4H10 (formerly 4H10)  
Immunohistochemical staining of paraffin-embedded prostate tissue within the normal limits using anti-DCXRmouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500819, Dilution 1:50) Mouse IgG1 OTI4H10 Purified Hu F, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

L-xylulose reductase antibody

  anti-DCXR mouse monoclonal antibody, clone OTI4D11 (formerly 4D11)  
Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-DCXRmouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500820, Dilution 1:50) Mouse IgG1 OTI4D11 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

L-xylulose reductase (C-term) antibody

  Goat Polyclonal Antibody against DCXR  
TA302809 staining (0.1µg/ml) of human kidney lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

L-xylulose reductase antibody

  Rabbit polyclonal antibody to L-xylulose reductase (dicarbonyl/L-xylulose reductase)  
Sample (30 ug of whole cell lysate). A: Hep G2 . 12% SDS PAGE. TA308568 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

L-xylulose reductase antibody

  Rabbit Polyclonal Anti-DCXR Antibody  
WB Suggested Anti-DCXR Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

L-xylulose reductase antibody

  anti-DCXR mouse monoclonal antibody, clone OTI9C9 (formerly 9C9)  
Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-DCXRmouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500830, Dilution 1:50) Mouse IgG1 OTI9C9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

L-xylulose reductase antibody

Formalin-Fixed, Paraffin-Embedded Human kidney carcinoma stained with DCXR Antibody (Center) Cat.-No AP14090PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Dcxr - mouse gene knockout kit via CRISPR

Dcxr - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Dcxr - mouse gene knockout kit via CRISPR

Dcxr - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dcxr - mouse gene knockout kit via CRISPR

Dcxr - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dcxr - mouse gene knockout kit via CRISPR

Dcxr - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

L-xylulose reductase

  Recombinant protein of human dicarbonyl/L-xylulose reductase (DCXR)  
L-xylulose reductase Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

L-xylulose reductase (transcript variant 2)

  Recombinant protein of human dicarbonyl/L-xylulose reductase (DCXR), transcript variant 2.  
L-xylulose reductase Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €399.00
  OriGene Technologies, Inc.

L-xylulose reductase (1-244, His-tag)

L-xylulose reductase Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

L-xylulose reductase (1-244, His-tag)

L-xylulose reductase Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

DCXR overexpression lysate

DCXR overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

DCXR overexpression lysate

DCXR overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DCXR (mGFP-tagged) - Human dicarbonyl/L-xylulose reductase (DCXR), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, DCXR (mGFP-tagged) - Human dicarbonyl/L-xylulose reductase (DCXR), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, DCXR (mGFP-tagged) - Human dicarbonyl/L-xylulose reductase (DCXR), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, DCXR (mGFP-tagged) - Human dicarbonyl/L-xylulose reductase (DCXR), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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