Lactotransferrin antibody

Principal name

Lactotransferrin antibody

Alternative names for Lactotransferrin antibody

LTF, LF, Lactoferrin, EC=3.4.21, Talalactoferrin

SwissProt ID

P02788 (Human), P08071 (Mouse), P14632 (Pig), P24627 (Bovin)

Gene ID

4057 (LTF), 280846, 4057117 (IPR003180)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Bov (Bovine), Mky (Monkey), Gt (Goat), Hst (Hamster)

Available hosts

Rabbit, Mouse, Sheep, Goat, Bovine

Available applications

Enzyme Immunoassay (E), Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoelectrophoresis (Ie), ELISA (detection) (E(detection)), ELISA (capture) (E(capture)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R), Immunodiffusion (ID), Dot blot (Dot), Flow Cytometry (F)

Background of Lactotransferrin antibody

Human lactoferrin (LF) is an 80 kDa glycoprotein which was first isolated from human milk. It plays an important part in the immune system and helps to fight infections. Lactoferrin promotes the health of the gastro-intestinal system by improving the intestinal microbial balance. In addition, LF can be found in epithelia and most body fluids and secretions.
Lactoferrin is secreted in plasma by neutrophils. Its plasma concentration also represents a positive relation to the total pool of neutrophils and the rate of neutrophil turnover. In inflammation lactoferrin is released from secondary granules of neutrophilic leukocytes into the extracellular medium. Therefore the extracellular lactoferrin concentration can be used as an index for neutrophil activation.
Lactoferrin strongly binds to iron and this iron binding property is considered to be an important antimicrobial. Human lactoferrin binds to bacterial products through its highly positively charged N-terminus, it kills various bacteria, most probably by inducing intracellular changes in these bacteria without affecting the membrane permeability. Cleavage by pepsin of lactoferrin leads to the release of lactoferricin H. This 47 amino acid peptide has more antimicrobial activity than its precursor and it can inhibit the classical but not the alternative complement pathway.
Lactoferrin also plays a role in signal transduction, immunomodulation and has antiadhesive, anticancer, antiviral activity.

General readings

Ashida K et al. Cellular internalization of lactoferrin in intestinal epithelial cells. Biometals 17:311-5 (2004). PubMed PMID: 15222483
Zimecki M et al. Protective effects of lactoferrin in Escherichia coli-induced bacteremia in mice: relationship to reduced serum TNF alpha level and increased turnover of neutrophils. Inflamm Res 53:292-6 (2004). PubMed PMID: 15241563
Sharma AK Purification, crystallization and preliminary crystallographic analysis of mare lactoferrin. Acta Crystallogr D Biol Crystallogr 52:1196-8 (1996). PubMed PMID: 15299585
Haridas M Structure of human diferric lactoferrin refined at 2.2 A resolution. Acta Crystallogr D Biol Crystallogr 51:629-46 (1995). PubMed PMID: 15299793

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 73 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Lactotransferrin antibody

Western blot analysis of lysate from K562 cell line, using LTF Antibody(Cat.  #TA324329).  TA324329 was diluted at 1:1000.  A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 35ug. Mouse IgG1 119CT80.1.1 Purified Hu ICC/IF, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Lactotransferrin antibody

TA305892 (0.05µg/ml) staining of Peripheral Blood Mononucleocyte lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Lactotransferrin antibody

Western blot analysis of LTF Antibody (Cat. #TA325064) in MDA-MB231 cell line lysates (35ug/lane). LTF (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Lactotransferrin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LTF (RC203140, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LTF. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Lactotransferrin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LTF (RC203140, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LTF. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Lactotransferrin antibody

AM08418PU-N LTF antibody staining of Formalin-Fixed, Paraffin-Embedded Human Breast, ductal with secretion at 10 µg/ml followed by biotinylated Goat anti-Rabbit IgG secondary
antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG1 1A1 Aff - Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG1 NI 25 Ascites Hu E, ICC/IF, IP, WB
0.5 mg / €360.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG1 NI 25 Biotin Hu E, ICC/IF, IP, WB
0.2 mg / €510.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG1 NI 25 FITC Hu E, ICC/IF, IP, WB
0.2 mg / €510.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG1 NI 25 HRP Hu E, ICC/IF, IP, WB
0.2 mg / €510.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG1 NI 25 Purified Hu E, ICC/IF, IP, WB
0.2 mg / €430.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG1 NI 25 TRITC Hu E, ICC/IF, IP, WB
0.2 mg / €510.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG2a KT33 Aff - Purified Hu E
1 mg / €910.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG2a KT33 Aff - Purified Hu E
0.2 mg / €450.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG2a KT33 Aff - Purified Hu E
0.1 mg / €450.00
  Acris Antibodies GmbH

Lactotransferrin (C-lobe) antibody

Lactotransferrin Mouse IgG1 a-bC-lobe Purified Bov, Gt, Hu E, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

Lactotransferrin (Lactoferricin-B) antibody

Lactotransferrin Mouse IgG1 5F12.1.2 Purified Bov E, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG1 265-1K1 Purified Hu C, E, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

Lactotransferrin (467-473) antibody

Lactotransferrin Mouse IgG1 a-bC-lobe Liquid Bov E, WB
0.1 mg / €630.00
  Acris Antibodies GmbH

Lactotransferrin antibody

Lactotransferrin Mouse IgG1 265-1K1 Liquid Hu C, E, WB
0.1 mg / €590.00
  Acris Antibodies GmbH

Items 1 to 20 of 73 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  • LinkedIn