Laforin antibody

Principal name

Laforin antibody

Alternative names for Laforin antibody

EPM2A, Laforin, EC=3.1.3.48, EC=3.1.3.16, Lafora PTPase, LAFPTPase

SwissProt ID

O95278 (Human)

Gene ID

7957 (EPM2A)

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of Laforin antibody

Epilepsy, progressive myoclonus type 2A (EPM2A), also known as laforin, is a dual-specificity phosphatase that associates with polyribosomes. The protein may be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules.

Defects in EPM2A are a cause of progressive myoclonic epilepsy type 2(EPM2), also known as Lafora disease. EPM2 is an autosomal recessive and severe form of adolescent-onset progressive epilepsy.p>

General readings

Minassian BA, Lee JR, Herbrick JA, et al. Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy. Nat. Genet. 1998; 20:171-4.
Worby CA, Gentry MS, and Dixon JE. Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates. J. Biol. Chem. 2006; 281:30412-8.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Laforin (Isoform A) antibody

TA305859 (0.1ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Laforin (C-term) antibody

Western blot analysis of SW480 in SW480 cell lysate with EPM2A antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Laforin antibody

Host: Rabbit; Target Name: EPM2A; Sample Tissue: THP-1 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Laforin antibody

Immunoblot against crude membrane fractions from whole rat (RBM) or mouse (MBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] probed with N84/37 (left) or N52A/42 (right) TC supe. Mouse IgG1 N84/37 Supernatant Hu ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Laforin antibody

Immunoblot against crude membrane fractions from whole rat (RBM) or mouse (MBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] probed with N84/37 (left) or N52A/42 (right) TC supe. Mouse IgG1 N84/37 Purified Hu ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Laforin antibody

Flow cytometr  analysis of EPM2A in HeLa cell line, staining at 2-5ug for 1x106 cells. The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Mouse IgG1 k2A3 Purified Hu E, F, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

Laforin antibody

Flow cytometr  analysis of EPM2A in HeLa cell line, staining at 2-5ug for 1x106 cells. The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Mouse IgG1 k2A3 Purified Hu E, F, WB
50 µl / €230.00
  Acris Antibodies GmbH

Laforin (C-term) antibody

Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with EPM2A antibody (C-term) (AP11437PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Laforin (C-term) Control Peptide

Laforin
50 µg / €160.00
  Acris Antibodies GmbH

Laforin antibody

Laforin Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Laforin antibody

Immunoprecipitation of EPM2A transfected lysate using anti-EPM2A MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with EPM2A MaxPab mouse polyclonal antibody (B01) (H00007957-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

Laforin antibody

Western Blot analysis of EPM2A expression in transfected 293T cell line (H00007957-T02) by EPM2A MaxPab polyclonal antibody.

Lane 1: EPM2A transfected lysate(37.20 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Laforin antibody

EPM2A monoclonal antibody (M01), clone 4A12. Western Blot analysis of EPM2A expression in PC-12 ( Cat # L012V1 ). Mouse IgG2a 4A12 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Laforin antibody

EPM2A monoclonal antibody (M02), clone 6C6 Western Blot analysis of EPM2A expression in PC-12 ( Cat # L012V1 ). Mouse IgG2a 6C6 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Laforin antibody

Cell lysates of HeLa ( lane 1 ) and 293T ( lane 2 ) ( 20 µg ) were resolved by SDS-PAGE and probed with EPM2A monoclonal antibody, clone k2A3 ( Cat # MAB2052 ) ( 1:1000 ). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 k2A3 Hu E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Laforin antibody

Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with EPM2A polyclonal antibody ( Cat # PAB3106 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Laforin antibody

EPM2A polyclonal antibody ( Cat # PAB11469 ) ( 0.1 µg/ml ) staining of human cerebellum lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Laforin antibody

Immunohistochemistry-Paraffin: Laforin Antibody [NBP1-18846] - 3.8ug/ml staining of paraffin embedded Human Cerebellum. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat IgG Aff - Purified Rt E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Laforin antibody

Laforin Mouse IgG1 k2A3 Purified Hu E, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

Laforin antibody

Western Blot:  EPM2A Antibody [NBP1-32052]- (30 µg of whole cell lysate) A:Raji(GTX27908) 12% SDS PAGE diluted at 1:5000 Rabbit IgG Hu ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

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