Lamin-B2 (LMNB2) antibody

Principal name

Lamin-B2 (LMNB2) antibody

Alternative names for Lamin-B2 (LMNB2) antibody

Lamin-B2, LMNB2, LMNB-2, LMN2, LMNB, Nuclear Envelope Marker

SwissProt ID

P14732 (Chick), P21619 (Mouse), Q03252 (Human)

Gene ID

84823 (LMNB2), 16907 (Lmnb2)

Available reactivities

Hst (Hamster), Hu (Human), Ms (Mouse), Por (Porcine), Xen (Xenopus), Ze (Zebrafish), Bov (Bovine), Chk (Chicken), Rt (Rat), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Can (Canine)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of Lamin-B2 (LMNB2) antibody

An important part of the cell nucleus is formed by nuclear lamina. Nuclear lamins form a network of filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. Lamin A, Lamin C and lamin Adel10, while the B-type lamins include two proteins arising from two distinct genes, i.e. Lamin B1 and Lamin B2.
The nuclear lamins comprise a unique subclass of the intermediate filament protein family. They share a molecular domain organisation with the other intermediate filament proteins in that they are fibrous molecules that have an aminoterminal globular head, a central rod of a-helices and a carboxyterminal globular domain. Many biochemical and molecular features of lamins have been studied, but their functions remain still largely undetermined. One of the functions ascribed to the lamina is the maintenance of the structural integrity of the nucleus. Besides interactions with the nuclear membrane and other intermediate filaments, lamins interact with the nuclear chromatin. Eukaryotic chromatin is organised into loops, which are attached to the nuclear matrix. This organisation is thought to contribute to compaction of the chromatin and regulation of gene expression. Lamins, as part of the nuclear matrix, may be involved in these processes since chromatin binding sites have been detected in both A- and B-type Lamins.

General readings

Abdurashidova,G., (2007) EMBO J. 26 (4), 998-1009

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Lamin-B2 (LMNB2) (221-460) antibody

  Rabbit polyclonal antibody to Lamin B2 (lamin B2)  
Sample (30 ug of whole cell lysate). A: H1299. B: Hela. C: Hep G2 . 7.5% SDS PAGE. TA308805 diluted at 1:1000. Rabbit Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Lamin-B2 (LMNB2) antibody

  Rabbit Polyclonal Anti-LMNB2 Antibody  
WB Suggested Anti-LMNB2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate.LMNB2 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Lamin-B2 (LMNB2) antibody

  Rabbit Polyclonal Anti-LMNB2 Antibody  
WB Suggested Anti-LMNB2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysateLMNB2 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Lamin-B2 (LMNB2) antibody

  Rabbit Polyclonal anti-Lamin B Antibody  
Western Blot analysis of HepG2 cell lysate with lamin B antibody Rabbit IgG Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Lamin-B2 (LMNB2) antibody

  LMNB2 mouse monoclonal antibody, clone OTI2C6 (formerly 2C6)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMNB2 (RC200807, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LMNB2. Mouse IgG1 OTI2C6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Lamin-B2 (LMNB2) (C-term) antibody

Western blot: AP20053PU-N Lamin B2 Antibody staining of Y79 cell line lysates (35 µg/lane). Lamin B2 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Lamin-B2 (LMNB2) antibody

BM4502 Lamin B2 antibody Immunostaining of Human epidermis. Mouse IgG1 LN43 Purified Hst, Hu, Ms, Por, Xen, Ze C, F, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

LMNB2 - human gene knockout kit via CRISPR

LMNB2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

LMNB2 - human gene knockout kit via CRISPR

LMNB2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

LMNB2 - human gene knockout kit via CRISPR

LMNB2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

LMNB2 - human gene knockout kit via CRISPR

LMNB2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmnb2 - mouse gene knockout kit via CRISPR

Lmnb2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Lmnb2 - mouse gene knockout kit via CRISPR

Lmnb2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmnb2 - mouse gene knockout kit via CRISPR

Lmnb2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmnb2 - mouse gene knockout kit via CRISPR

Lmnb2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Lamin-B2 (LMNB2)

  Recombinant protein of human lamin B2 (LMNB2)  
Lamin-B2 (LMNB2) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Lmnb2 (GFP-tagged) - Mouse lamin B2 (Lmnb2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lmnb2 (GFP-tagged) - Mouse lamin B2 (Lmnb2), 200 uL, >10^7 TU/mL  
200 µl / €1,250.00
  OriGene Technologies, Inc.

Lenti ORF particles, Lmnb2 (Myc-DDK-tagged) - Mouse lamin B2 (Lmnb2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lmnb2 (Myc-DDK-tagged) - Mouse lamin B2 (Lmnb2), 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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