Laminin alpha 1 antibody

Principal name

Laminin alpha 1 antibody

Alternative names for Laminin alpha 1 antibody

LAMA1, LAMA, Laminin subunit alpha-1, Laminin A chain

SwissProt ID

P19137 (Mouse), P25391 (Human)

Gene ID

284217 (LAMA1), 16772 (Lama1)

Available reactivities

Av (Birds), Chk (Chicken), Hu (Human), Rb (Rabbit), Ms (Mouse), Rt (Rat), Fe (Feline), Por (Porcine)

Available hosts

Rabbit, Rat, Mouse

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Radioimmunoassay (R), Immunoprecipitation (IP)

Background of Laminin alpha 1 antibody

Laminin, the most abundant structural and biologically active component in basement membranes, is a complex extracellular glycoprotein with an approximate molecular weight of 900 kDa. It plays an important role in many aspects of the cell biology. Laminin is composed of one A chain (400 kDa) one B1 chain (215 kDa) and one B2 chain (205 kDa) all held together by disulfide bonds. The molecule has a cross like form with globular units near the ends of each chain, the sites where it is bound to Collagen IV, heparan sulfate, proteoglycan as well as to the surface of epithelial cells. Laminins from various species have common antigenic determinants. Laminin is only found in significant quantities in basement membranes, the thin extracellular matrices that surround epithelial tissue, nerve, fat cells and smooth, striated and cardiac muscle. It has been found to modulate cell differentiation, cell shaping and also cell movement because it appears to be an important cell substrate adhesion protein. Variations in the expression of this protein have been observed in embryogenesis, organogenesis, post traumatic healing and cancer. The greatest interest in laminin has been provoked by the discovery of its ability to promote neurite regeneration.

General readings

General / background references:Gordon-Weeks PR et al. A study of the expression of laminin in the spinal cord of the frog during development and regeneration. Exp Physiol 77:681-92 (1992). PubMed PMID: 1418951
Gordon-Weeks PR et al. Transient expression of laminin immunoreactivity in the developing rat hippocampus. J Neurocytol 18:451-63 (1989). PubMed PMID: 2509639

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Laminin alpha 1 antibody

Western Blot: Laminin Antibody - Detection of laminin by Western blot using anti-Laminin. Rabbit Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Laminin alpha 1 antibody

Immunofluorescence analysis of COS-7 cells, using LAMA1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

Laminin alpha 1 antibody

Predicted cell location: Cytoplasm. Positive control: Human colon and lung cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human colon and lung cancer tissue using LAMA1 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Laminin alpha 1 antibody

Predicted cell location: Cytoplasm. Positive control: Human brain and colon cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human brain and colon cancer tissue using LAMA1 antibody at dilution 1/70, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Laminin alpha 1 antibody

Staining of Lama1 on rat spinal cord and dorsal root paraformaldehyde/paraffin-embedded tissue using Lama1 polyclonal antibody ( Cat # PAB12133 ). Pepsin antigen retrieval was performed on this tissue sample. Rabbit Hu, Ms, Rt C, P, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

Laminin alpha 1 antibody

Rat peripheral nerve ( low and high magnification; formalin-fixed, frozen sections ). Immuno-FITC stain ( color inverted ) with Lama1 polyclonal antibody ( Cat # PAB13719 ) ( 1 : 1,000 ). Rabbit Hu, Ms, Rt C, ICC/IF, WB
0.2 ml / €560.00
  Abnova Taiwan Corp.

Laminin alpha 1 antibody

Immunofluorescence analysis of COS7 cells, using LAMA1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
50 µg / €205.00
  Assay Biotech

Laminin alpha 1 antibody

Immunofluorescence analysis of COS7 cells, using LAMA1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

Laminin alpha 1 antibody

Laminin alpha 1 Mouse IgG1 LAM-26 Ascites Fe, Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

Laminin alpha 1 antibody

Laminin alpha 1 Rabbit Biotin Hu, Ms, Rt C, P, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

Laminin alpha 1 antibody

Laminin alpha 1 Rabbit DyLight488 Hu, Ms, Rt C, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

Laminin alpha 1 antibody

Laminin alpha 1 Rabbit HRP Hu, Ms, Rt C, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

Laminin alpha 1 antibody

Laminin alpha 1 Rabbit DyLight549 Hu, Ms, Rt C, P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

Laminin alpha 1 antibody

Laminin alpha 1 Rabbit Serum Av, Chk, Hu, Rb C, E, ICC/IF, P
0.125 ml / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Laminin alpha 1

Laminin Protein [NBP1-78301] - Neurite outgrowth on Laminin-1 substratum Human Purified
1 mg / €140.00
  Novus Biologicals Inc.

ELISA Kits

Catalog No.    

Human Laminin ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

Mouse Laminin ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

17 Item(s)

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