Laminin gamma 1 antibody

Principal name

Laminin gamma 1 antibody

Alternative names for Laminin gamma 1 antibody

LAMC1, LAMB2, Laminin subunit gamma-1, Laminin B2 chain

SwissProt ID

P02468 (Mouse), P11047 (Human)

Gene ID

3915 (LAMC1)

Available reactivities

Hu (Human), Ms (Mouse), GP (Guinea Pig), Rt (Rat), Por (Porcine), Ze (Zebrafish), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit)

Available hosts

Mouse, Rat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Frozen Sections (C)

Background of Laminin gamma 1 antibody

Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Gamma-1 is a subunit of laminin-1 (EHS laminin), laminin-2 (merosin), laminin-3 (S-laminin), laminin-4 (S-merosin), laminin-6 (K-laminin) and laminin-7 (KS-laminin). Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Laminin gamma 1 antibody

Western blot analysis of extracts from HUVEC cells, using LAMC1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Laminin gamma 1 antibody

WB Suggested Anti-LAMC1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Laminin gamma 1 antibody

WB Suggested Anti-LAMC1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Laminin gamma 1 antibody

Laminin gamma 1 Mouse IgG1 BC17 Ig Fraction Hu C, E, IP
0.1 mg / €430.00
  Acris Antibodies GmbH

Laminin gamma 1 antibody

Immunohistochemistry of Laminin gamma-1 Cat.-No AP02273SU staining in Paraffin section of a 18-month-old Mouse retina. Antigen retrieval was performed in 0.005% Trypsin at 37°C for 10 min. The section was incubated with AP02273SU overnight followed by incubation with Alexa488 anti Rabbit antibody (1/1000). This antibody stains Bruch's membrane, the capillary basement membranes and the inner limiting membrane. Kunze A el. (2010) Ophthalmic Res 43(2): 108-112. Rabbit Serum Ms C, P, WB
0.1 ml / €540.00
  Acris Antibodies GmbH

Laminin gamma 1 antibody

Immunohistochemistry of Laminin gamma-1 Cat.-No AP02273SU staining in Paraffin section of a 18-month-old Mouse retina. Antigen retrieval was performed in 0.005% Trypsin at 37°C for 10 min. The section was incubated with AP02273SU overnight followed by incubation with Alexa488 anti Rabbit antibody (1/1000). This antibody stains Bruch's membrane, the capillary basement membranes and the inner limiting membrane. Kunze A el. (2010) Ophthalmic Res 43(2): 108-112. Rabbit Serum Ms C, P, WB
20 µl / €190.00
  Acris Antibodies GmbH

Laminin gamma 1 antibody

Immunohistochemistry (IHC) analyzes of Laminin gamma-1 antibody (Cat.-No.: AP20488PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Laminin gamma 1 antibody

Laminin gamma 1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Laminin gamma 1 antibody

Detection limit for recombinant GST tagged LAMC1 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 2E6-B4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Laminin gamma 1 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between LAMA5 and LAMC1 HeLa cells were stained with anti-LAMA5 rabbit purified polyclonal 1:1200 and anti-LAMC1 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG2a M1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Laminin gamma 1 antibody

Laminin gamma 1 Mouse IgG1 BC17 Hu IP, P
0.1 mg / €560.00
  Abnova Taiwan Corp.

Laminin gamma 1 antibody

Western blot analysis of extracts from HuvEc cells, using LAMC1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

Laminin gamma 1 antibody

Western blot analysis of extracts from HuvEc cells, using LAMC1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

Laminin gamma 1 antibody

Hum. Adult Placenta; Host:Rabbit. Target Name:LAMC1. Sample Tissue:Human Adult Placenta. Antibody Dilution: 1.0ug/ml.; LAMC1 antibody - middle region (ARP58233_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Laminin gamma 1 antibody

Human Placenta; WB Suggested Anti-LAMC1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Placenta; LAMC1 antibody - middle region (ARP58234_P050) in Human Placenta cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Laminin gamma 1 antibody

Laminin gamma 1 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

Laminin gamma 1 antibody

Western Blot: Laminin gamma-1 Antibody [NBP1-19643] - extracts from HUVEC cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Laminin gamma 1 antibody

Western Blot: Laminin gamma 1 Antibody [NBP1-59144] - This Anti-LAMC1 antibody was used in Western Blot of Placenta tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Laminin gamma 1 antibody

Immunohistochemistry-Paraffin: Laminin gamma 1 Antibody [NBP1-87718] - Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic and decidual cells. Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Laminin gamma 1

Laminin gamma 1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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