LAMTOR1 antibody

Principal name

LAMTOR1 antibody

Alternative names for LAMTOR1 antibody

C11orf59, PDRO, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1, Lipid raft adaptor protein p18, Protein associated with DRMs and endosomes, p27Kip1-releasing factor from RhoA, p27RF-Rho, Ragulator complex protein LAMTOR1

Gene ID

55004 (LAMTOR1)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C)

Background of LAMTOR1 antibody

The Ragulator complex is comprised of three proteins, C11orf59, ROBLD3, and MAPKSP1, which targets mTORC1 to lysosomal surfaces. This normal endosomal trafficking is taken advantage of by certain viruses, including coronavirus, which has increased replication when C11orf59 is interfered with. C11orf59 is positively regulated by cellular cholesterol depletion and negatively regulated by cellular cholesterol loading. It is involved in LDL uptake and cholesterol homeostasis. C11orf59 and PPAR-alpha work together to control lipid and carbohydrate metabolism in diabetes. Nearly all effects of C11orf59 are associated with mTORC1 kinase growth promotion, and disregulation of the normal mTOR pathway.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LAMTOR1 antibody

Western Blot: C11orf59 Antibody - WB analysis of c11orf59 in human liver protein. Rabbit Purified Bov, Hu, Ms, Rt C, ICC/IF, WB
50 µl / €325.00
  OriGene Technologies, Inc.

LAMTOR1 antibody

Western blot analysis of LAMTOR1 in A431 cell lysate with LAMTOR1 antibody at 1 ug/ml. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LAMTOR1 antibody

LAMTOR1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

LAMTOR1 antibody

Immunohistochemistry-Paraffin: C11orf59 Antibody [NBP1-89909] - Immunohistochemical staining of human rectum shows strong cytoplasmic positivity, with a granular pattern, in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

4 Item(s)

per page
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