LARP7 antibody

Principal name

LARP7 antibody

Alternative names for LARP7 antibody

LARP7, La-related protein 7, La ribonucleoprotein domain family member 7, P-TEFb-interaction protein for 7SK stability, PIP7S

SwissProt ID

LARP7, Q4G0J3 (Human)

Gene ID

51574 (LARP7)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of LARP7 antibody

In eukaryotic cells, RNA-binding proteins (RBPs) contribute to gene expression by regulating the form, abundance, and stability of both coding and non-coding RNAs. In the vertebrate brain, RBPs account for many distinctive features of RNA processing such as activity-dependent transcript localization and localized protein synthesis. There are 380 putative RBPs in the mouse genome that are identified, at least 323 of them are expressed in embryonic age 13.5 and post natal age 0 when critical signals are required for development of major structural differentiation. Sixteen out of 323 genes are neuronal specific and majority of these genes (221 out of 323) exhibit regionally restricted expression (1). The initiation of human embryo implantation process resulted in expression of a large number of RBPs that are derived from extra-embryonic cells. These genes are under tight control of expression during development.
One of these several genes is La riboneucleoprotein domain family member 7 (LaRP7). These proteins are expressed in embryonic ovary testis and brain. LaRP is expressed in testis of adult sex-reversed mice which lack the germ cell and therefore represent a meiosis-specific gene. It is part of the mouse multigene family, member of which are mapped to a single region of the X-chromosome. The LaRP7 contains several function domains including a domain in the RNA binding Lupus La protein of unknown function, a RNA recognition motif (RRM) which is diagnostic to the RNA binding protein and a LHP1 domain which is binding site for small RNA-RNA polymerase III transcript stabilizing protein and related La-motif-containing proteins involved in translation. The HDCMA18P is similar to LARP family member 7 protein from amino acid 382-595, it represents only the lower 50% of LARP7 protein of various variants.

General readings

Tyagi, M., et al. J. Virol. 84(13):6425-6437(2010)
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Markert, A., et al. EMBO Rep. 9(6):569-575(2008)
Krueger, B.J., et al. Nucleic Acids Res. 36(7):2219-2229(2008)
He, N., et al. Mol. Cell 29(5):588-599(2008).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LARP7 antibody

  Rabbit Polyclonal Anti-LARP7 Antibody  
WB Suggested Anti-LARP7 Antibody Titration: 0.2-1 ug/ml; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

LARP7 antibody

  Rabbit Polyclonal Anti-LARP7 Antibody  
WB Suggested Anti-LARP7 Antibody Titration: 1.25 ug/ml; Positive Control: Jurkat cell lysateLARP7 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LARP7 Control Peptide

LARP7
0.25 mg / €250.00
  Acris Antibodies GmbH

LARP7 (384-403) antibody

Western blot with AP10119PU-N at 1:500. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

LARP7 (C-term) antibody

Western blot analysis of LARP7 Antibody (C-term) Cat.-No AP52443PU-N in WiDr cell line lysates (35ug/lane). This demonstrates the LARP7 antibody detected the LARP7 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

LARP7 - human gene knockout kit via CRISPR

LARP7 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

LARP7 - human gene knockout kit via CRISPR

LARP7 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

LARP7 - human gene knockout kit via CRISPR

LARP7 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

LARP7 - human gene knockout kit via CRISPR

LARP7 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

LARP7 overexpression lysate

LARP7 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, LARP7 (mGFP-tagged) - Human La ribonucleoprotein domain family, member 7 (LARP7), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, LARP7 (mGFP-tagged) - Human La ribonucleoprotein domain family, member 7 (LARP7), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,230.00
  OriGene Technologies, Inc.

Lenti ORF particles, LARP7 (Myc-DDK tagged) - Human La ribonucleoprotein domain family, member 7 (LARP7), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, LARP7 (Myc-DDK tagged) - Human La ribonucleoprotein domain family, member 7 (LARP7), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €1,100.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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