LASS5 antibody

Principal name

LASS5 antibody

Alternative names for LASS5 antibody

LASS5, LAG1 longevity assurance homolog 5, TRH4, TRAM homolog 4, Translocating chain-associating membrane protein homolog 4

SwissProt ID

Q8N5B7 (Human), Q9D6K9 (Mouse)

Gene ID

91012 (CERS5), 71949 (Lass5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), African clawed frog, Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of LASS5 antibody

The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein. Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner. It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide. LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia. Recent studies show that LASS5 partially correct growth and apoptosis. Multiple isoforms of LASS5 are known to exist.

General readings

Kitatani,K., (2006) J. Biol. Chem. 281 (48), 36793-36802

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LASS5 (C-term) antibody

  Rabbit Polyclonal LASS5 Antibody  
Western blot analysis of LASS5 in SK-N-SH lysate with LASS5 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LASS5 (N-term) antibody

  Rabbit Polyclonal LASS5 Antibody  
Western blot analysis of LASS5 in rat brain tissue lysate with LASS5 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LASS5 antibody

  Rabbit Polyclonal LASS5 Antibody  
Western blot analysis of LASS5 in SK-N-SH lysate with LASS5 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LASS5 antibody

  Rabbit Polyclonal Anti-LASS5 Antibody  
WB Suggested Anti-LASS5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Pancreas Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

LASS5 antibody

  Rabbit Polyclonal Anti-LASS5 Antibody  
WB Suggested Anti-LASS5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Human kidney Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

LASS5 antibody

  Rabbit Polyclonal Anti-CERS5 Antibody  
LASS5 Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LASS5 (C-term) antibody

Human Small Intestine (formalin-fixed, paraffin-embedded) stained with LASS5 antibody AP22658PU-N at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Cers5 - mouse gene knockout kit via CRISPR

Cers5 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cers5 - mouse gene knockout kit via CRISPR

Cers5 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cers5 - mouse gene knockout kit via CRISPR

Cers5 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cers5 - mouse gene knockout kit via CRISPR

Cers5 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Lass5 (GFP-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lass5 (GFP-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704), 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Lass5 (Myc-DDK-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lass5 (Myc-DDK-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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