Latrophilin-1 / AGRL1 antibody

Principal name

Latrophilin-1 / AGRL1 antibody

Alternative names for Latrophilin-1 / AGRL1 antibody

LPHN1, KIAA0821, LEC2, Latrophilin-1, Calcium-independent alpha-latrotoxin receptor 1, Lectomedin-2, Adhesion G protein-coupled receptor L1

SwissProt ID

O88917, O94910 (Human), O97831, Q80TR1

Gene ID

22859 (LPHN1), 65096 (Lphn1), 330814

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Bt (Bat), Hst (Hamster), Mky (Monkey), Por (Porcine), Rb (Rabbit), Xen (Xenopus), L (Lizard), Bear

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Latrophilin-1 / AGRL1 antibody

Latrophilins (Latrophilin1-3) are members of the adhesion G-protein coupled receptor subfamily. Like all GPCRs, Latrophilins have seven transmembrane domains and are distinguished by a large extracellular N-termil tail and a large intracellular C-termil tail1. The N-terminus has several cell adhesion domains and undergoes proteolysis after synthesis, while the C-termil has various consensus post-translatiol sites like phosphorylation and palmitoylation. In addition, Latrophilins undergo altertive splicing.Latrophilin-1 was discovered by its ability to bind a-Latrotoxin (a-LTX), a toxin isolated from the black widow spider venom. a-LTX induces exocytosis by creating a Ca2+ influx in the presyptic membrane. a-LTX can also stimulate small vesicle exocytosis in a Ca2+ independent manner. Three receptors have been found to bind a-LTX. Of the three, Latrophilins are responsible for the Ca2+-independent effects of a-LTX2. The binding of a-LTX to Latrophilin-1 increases exocytosis of neurotransmitters.In an attempt to find the tural ligand of Latrophilin-1, Lasso, a splice variant of Teneneurin-2 was discovered to be an endogenous binding partner of the adhesion-GPCR7. Teneneurins are large glycoproteins with a single transmembrane domain. Like Latrophilin-1, Teneneurins are mostly expressed in the brain where they modulate neurite outgrowth, axon guidance and syptogenesis.Regarding the localization of Latrophilins, Latrophilin-1 is expressed predomintly in the brain, Latrophilin-2 is highly expressed in the liver and lung, while Latrophilin-3 is almost exclusively detected in the brain.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Latrophilin-1 / AGRL1 antibody

  Rabbit polyclonal anti-LPHN1 antibody  
Immunofluorescence analysis of LOVO cells, using LPHN1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

Latrophilin-1 / AGRL1 antibody

  Rabbit Polyclonal Anti-Latrophilin-1 (extracellular)  
Western blot analysis of rat brain (lanes 1 and 3) and mouse brain (lanes 2 and 4) lysates: 1, 2. Anti-Latrophilin-1 (extracellular) antibody, (1:200). 3, 4. Anti-Latrophilin-1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Latrophilin-1 / AGRL1 antibody

  Rabbit Polyclonal Anti-LPHN1 Antibody  
WB Suggested Anti-LPHN1 Antibody; Titration: 1.0 ug/ml; Positive Control: Hela Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Latrophilin-1 / AGRL1 (extracell. dom.) (N-term) antibody

  Rabbit Polyclonal Anti-LPHN1 Antibody (N-Terminus)  
Anti-LPHN1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Hst, Hu, L, Mky, Ms, Op, Platypus, Por, Rb, Rt, Xen P
50 µg / €379.00
  OriGene Technologies, Inc.

Latrophilin-1 / AGRL1 antibody

  Rabbit Polyclonal Anti-LPHN1 Antibody (C-Terminus)  
Anti-LPHN1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Bov, Eq, Hu, Por
50 µg / €379.00
  OriGene Technologies, Inc.

Latrophilin-1 / AGRL1 antibody

Western Blot analysis of LPHN1 expression in transfected 293T cell line (H00022859-T04) by LPHN1 MaxPab polyclonal antibody.

Lane 1: LPHN1 transfected lysate(20.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Latrophilin-1 / AGRL1 antibody

Latrophilin-1 / AGRL1 Mouse IgG2a 4E12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Latrophilin-1 / AGRL1 antibody

Immunofluorescence analysis of LOVO cells, using LPHN1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €205.00
  Assay Biotech

Latrophilin-1 / AGRL1 antibody

Immunofluorescence analysis of LOVO cells, using LPHN1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Latrophilin-1 / AGRL1

Latrophilin-1 / AGRL1 Human
10 µg / €540.00
  Abnova Taiwan Corp.

Latrophilin-1 / AGRL1

Latrophilin-1 / AGRL1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Latrophilin-1 / AGRL1

Latrophilin-1 / AGRL1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Latrophilin-1 / AGRL1

Latrophilin-1 / AGRL1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Latrophilin-1 / AGRL1

Latrophilin-1 / AGRL1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, LPHN1 (mGFP-tagged)-Human latrophilin 1 (LPHN1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, LPHN1 (mGFP-tagged)-Human latrophilin 1 (LPHN1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, LPHN1 (mGFP-tagged)-Human latrophilin 1 (LPHN1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, LPHN1 (mGFP-tagged)-Human latrophilin 1 (LPHN1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, LPHN1 (Myc-DDK-tagged)-Human latrophilin 1 (LPHN1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, LPHN1 (Myc-DDK-tagged)-Human latrophilin 1 (LPHN1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

Lenti ORF particles, LPHN1 (Myc-DDK-tagged)-Human latrophilin 1 (LPHN1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, LPHN1 (Myc-DDK-tagged)-Human latrophilin 1 (LPHN1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Lphn1 (GFP-tagged) - Mouse latrophilin 1 (Lphn1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lphn1 (GFP-tagged) - Mouse latrophilin 1 (Lphn1), 200 uL, >10^7 TU/mL  
200 µl / €2,390.00
  OriGene Technologies, Inc.

Lenti ORF particles, Lphn1 (Myc-DDK-tagged) - Mouse latrophilin 1 (Lphn1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lphn1 (Myc-DDK-tagged) - Mouse latrophilin 1 (Lphn1), 200 uL, >10^7 TU/mL  
200 µl / €2,160.00
  OriGene Technologies, Inc.

20 Item(s)

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