LATS1 antibody

Principal name

LATS1 antibody

Alternative names for LATS1 antibody

LATS1, WARTS, Serine/threonine-protein kinase LATS1, EC=2.7.11.1, Large tumor suppressor homolog 1, WARTS protein kinase, h-warts

SwissProt ID

O95835 (Human), Q8BYR2 (Mouse)

Gene ID

9113 (LATS1), 16798 (Lats1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of LATS1 antibody

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LATS1 antibody

  Rabbit polyclonal anti-LATS1/2 antibody  
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using LATS1/2 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

LATS1 antibody

  Rabbit polyclonal LATS1/2 (Thr1079/1041) antibody(Phospho-specific)  
Immunohistochemistry analysis of paraffin-embedded human brain tissue using LATS1/2 (Phospho-Thr1079/1041) antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

LATS1 antibody

  Rabbit polyclonal anti-LATS1 antibody  
Western blot analysis of extracts from A549 cells and K562 cells, using LATS1 Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LATS1 antibody

  Rabbit Polyclonal Anti-LATS1 Antibody - middle region  
WB Suggested Anti-LATS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

LATS1 antibody

  Rabbit Polyclonal Anti-LATS1 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (LATS1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

LATS1 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu, Ms, Rt P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

LATS1 pThr1079/1041 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using LATS1/2 (Phospho-Thr1079/1041) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
50 µg / €230.00
  Assay Biotech

LATS1 pThr1079/1041 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using LATS1/2 (Phospho-Thr1079/1041) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
0.1 mg / €330.00
  Assay Biotech

LATS1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using LATS1/2 (Ab-1079/1041) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
50 µg / €230.00
  Assay Biotech

LATS1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using LATS1/2 (Ab-1079/1041) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
0.1 mg / €330.00
  Assay Biotech

LATS1 / LATS2 pThr1079/1041 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using LATS1/2 (Phospho-Thr1079/1041) antibody AP55760PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms P
0.1 ml / €340.00
  Acris Antibodies GmbH

LATS1 / LATS2 pThr1079/1041 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using LATS1/2 (Phospho-Thr1079/1041) antibody AP55760PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms P
50 µl / €270.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

LATS1 - human gene knockout kit via CRISPR

LATS1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

LATS1 - human gene knockout kit via CRISPR

LATS1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

LATS1 - human gene knockout kit via CRISPR

LATS1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

LATS1 - human gene knockout kit via CRISPR

LATS1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lats1 - mouse gene knockout kit via CRISPR

Lats1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Lats1 - mouse gene knockout kit via CRISPR

Lats1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lats1 - mouse gene knockout kit via CRISPR

Lats1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lats1 - mouse gene knockout kit via CRISPR

Lats1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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