LDLRAP1 antibody

Principal name

LDLRAP1 antibody

Alternative names for LDLRAP1 antibody

LDLRAP1, ARH, Low density lipoprotein receptor adapter protein 1, Autosomal recessive hypercholesterolemia protein

SwissProt ID

Q5SW96 (Human), Q8C142 (Mouse)

Gene ID

26119 (LDLRAP1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Luminex (LMNX)

Background of LDLRAP1 antibody

LDLRAP1 is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. This adapter protein is required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). LDLRAP1 may be required for LDL binding and internalization but not for receptor clustering in coated pits. This protein may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits, and may also be involved in the internalization of other LDLR family members. Mutations in the LDLRAP1 gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.

General readings

He G, Gupta S, Yi M, Michaely P, Hobbs HH, Cohen JC.
ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2.
J Biol Chem. 2002 Nov 15;277(46):44044-9.
PMID: 12221107

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LDLRAP1 antibody

  LDLRAP1 (ARH) mouse monoclonal antibody, clone OTI4B10 (formerly 4B10)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-LDLRAP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503846) Mouse IgG1 OTI4B10 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LDLRAP1 antibody

  LDLRAP1 (ARH) mouse monoclonal antibody, clone OTI7E11 (formerly 7E11)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-LDLRAP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503854) Mouse IgG1 OTI7E11 Purified Hu F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

LDLRAP1 antibody

  Luminex validated LDLRAP1 mouse monoclonal antibody (clone 2B2, clone OTI2B2 (formerly 2B2)  
LDLRAP1 Elisa with 2B2 Capture (TA600146) and 4B10 Detection (TA700148) Antibodies. Substrate used: Recombinant Human LDLRAP1 (TP306643) Mouse IgG1 OTI2B2 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

LDLRAP1 antibody

  Luminex validated LDLRAP1 mouse monoclonal antibody (clone 7E1, clone OTI7E11 (formerly 7E11)  
LDLRAP1 Elisa with 7E11 Capture (TA600148) and 7G2 Detection (TA700147) Antibodies. Substrate used: Recombinant Human LDLRAP1 (TP306643) Mouse IgG1 OTI7E11 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

LDLRAP1 antibody

  Luminex validated biotinylated LDLRAP1 mouse monoclonal antibody (clone 7G2), clone OTI7G2 (formerly 7G2)  
LDLRAP1 Elisa with 4B10 Capture (TA600147) and 7G2 Detection (TA700147) Antibodies. Substrate used: Recombinant Human LDLRAP1 (TP306643) Mouse IgG1 OTI7G2 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

LDLRAP1 antibody

  Luminex validated biotinylated LDLRAP1 mouse monoclonal antibody (clone 4B10), clone OTI4B10 (formerly 4B10)  
LDLRAP1 Elisa with 7G2 Capture (TA600149) and 4B10 Detection (TA700148) Antibodies. Substrate used: Recombinant Human LDLRAP1 (TP306643) Mouse IgG1 OTI4B10 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

LDLRAP1 antibody

Human Small Intestine, muscularis propria: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 4G4-D5 Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

LDLRAP1 (N-term) antibody

  Goat Polyclonal Antibody against LDLRAP1  
TA302878 staining (3µg/ml) of Human Liver lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LDLRAP1 antibody

  LDLRAP1 (ARH) mouse monoclonal antibody, clone OTI1F3 (formerly 1F3)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LDLRAP1 (RC206643, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LDLRAP1. Mouse IgG1 OTI1F3 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LDLRAP1 antibody

  LDLRAP1 (ARH) mouse monoclonal antibody, clone OTI2B2 (formerly 2B2)  
Anti-LDLRAP1 mouse monoclonal antibody (TA503840) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LDLRAP1(RC206643). Mouse IgG1 OTI2B2 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LDLRAP1 antibody

  LDLRAP1 (ARH) mouse monoclonal antibody, clone OTI7G2 (formerly 7G2)  
Anti-LDLRAP1 mouse monoclonal antibody (TA503841) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LDLRAP1(RC206643). Mouse IgG1 OTI7G2 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LDLRAP1 antibody

  LDLRAP1 (ARH) mouse monoclonal antibody, clone OTI3H10 (formerly 3H10)  
Anti-LDLRAP1 mouse monoclonal antibody (TA503845) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LDLRAP1(RC206643). Mouse IgG1 OTI3H10 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LDLRAP1 antibody

  LDLRAP1 (ARH) mouse monoclonal antibody, clone OTI5A12 (formerly 5A12)  
Anti-LDLRAP1 mouse monoclonal antibody (TA503851) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LDLRAP1(RC206643). Mouse IgG1 OTI5A12 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LDLRAP1 antibody

  LDLRAP1 (ARH) mouse monoclonal antibody, clone OTI7H10 (formerly 7H10)  
Anti-LDLRAP1 mouse monoclonal antibody (TA503853) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LDLRAP1(RC206643). Mouse IgG1 OTI7H10 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LDLRAP1 antibody

  LDLRAP1 (ARH) mouse monoclonal antibody, clone OTI7A5 (formerly 7A5)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LDLRAP1 (RC206643, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LDLRAP1. Mouse IgG1 OTI7A5 Purified Can, Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LDLRAP1 antibody

  LDLRAP1 (ARH) mouse monoclonal antibody, clone OTI4G5 (formerly 4G5)  
Anti-LDLRAP1 mouse monoclonal antibody (TA503856) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LDLRAP1(RC206643). Mouse IgG1 OTI4G5 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LDLRAP1 antibody

  Luminex validated LDLRAP1 mouse monoclonal antibody (clone 4B1, clone OTI4B10 (formerly 4B10)  
LDLRAP1 Elisa with 4B10 Capture (TA600147) and 7G2 Detection (TA700147) Antibodies. Substrate used: Recombinant Human LDLRAP1 (TP306643) Mouse IgG1 OTI4B10 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

LDLRAP1 antibody

  Luminex validated LDLRAP1 mouse monoclonal antibody (clone 7G2, clone OTI7G2 (formerly 7G2)  
LDLRAP1 Elisa with 7G2 Capture (TA600149) and 4B10 Detection (TA700148) Antibodies. Substrate used: Recombinant Human LDLRAP1 (TP306643) Mouse IgG1 OTI7G2 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

LDLRAP1 antibody

  Luminex validated biotinylated LDLRAP1 mouse monoclonal antibody (clone 1F3), clone OTI1F3 (formerly 1F3)  
LDLRAP1 Elisa with 2B2 Capture (TA600146) and 1F3 Detection (TA700146) Antibodies. Substrate used: Recombinant Human LDLRAP1 (TP306643) Mouse IgG1 OTI1F3 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

LDLRAP1 antibody

  Luminex validated biotinylated LDLRAP1 mouse monoclonal antibody (clone 5A12), clone OTI5A12 (formerly 5A12)  
LDLRAP1  Elisa with 2B2 Capture (TA600146) and 5A12 Detection (TA700149) Antibodies. Substrate used: Recombinant Human LDLRAP1 (TP306643) Mouse IgG1 OTI5A12 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

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