Legumain antibody

Principal name

Legumain antibody

Alternative names for Legumain antibody

LGMN, PRSC1, Legumain, EC=3.4.22.34, Asparaginyl endopeptidase, Protease, cysteine 1

SwissProt ID

O89017 (Mouse), Q95M12 (Bovin), Q99538 (Human), Q9R0J8 (Rat)

Gene ID

5641 (LGMN)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish), Sh (Sheep)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP)

Background of Legumain antibody

This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq]. Transcript Variant: This variant (2) has an additional exon in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Shirahama-Noda K., et al. (2003) J. Biol. Chem. 278:33194-33199.Liu C., et al. (2003) Cancer Res. 63:2957-2964.

17 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Legumain antibody

WB Suggested Anti-LGMN Antibody; Titration: 1.0 ug/ml; Positive Control: HepG2 Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Legumain antibody

WB Suggested Anti-LGMN Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Legumain antibody

Immunoperoxidase of purified MaxPab antibody to LGMN on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Mouse Purified Hu E(detection), P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Legumain antibody

LGMN MaxPab rabbit polyclonal antibody. Western Blot analysis of LGMN expression in HeLa. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Legumain antibody

Western Blot analysis of LGMN expression in transfected 293T cell line (H00005641-T01) by LGMN MaxPab polyclonal antibody.

Lane 1: LGMN transfected lysate(49.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Legumain antibody

Detection limit for recombinant GST tagged LGMN is approximately 0.1ng/ml as a capture antibody. Mouse IgG1 M1 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Legumain antibody

Legumain Mouse IgG1 M2 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Legumain antibody

Immunohistochemistry-Paraffin: Legumain Antibody [NBP1-87793] - Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Legumain (transcript variant 1)

Legumain Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Legumain (transcript variant 2)

Legumain Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €399.00
  OriGene Technologies, Inc.

Legumain (18-435, His-tag)

Legumain Mouse Purified > 90 % by SDS – PAGE Insect cells
0.25 mg / €940.00
  Acris Antibodies GmbH

Legumain (18-435, His-tag)

Legumain Mouse Purified > 90 % by SDS – PAGE Insect cells
50 µg / €300.00
  Acris Antibodies GmbH

Legumain

Legumain Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

LGMN (Human) IP-WB Antibody Pair

LGMN (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

LGMN (Human) IP-WB Antibody Pair

LGMN (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

LGMN (Human) Matched Antibody Pair

LGMN (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

Legumain Lysate(Denatured)

Legumain Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

17 Item(s)

per page
  • LinkedIn