LFNG antibody

Principal name

LFNG antibody

Alternative names for LFNG antibody

LFNG, EC=2.4.1.222, Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

SwissProt ID

O09010 (Mouse), O12971 (Chick), Q2KJ92 (Bovin), Q8NES3 (Human), Q924T4 (Rat)

Gene ID

3955 (LFNG)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of LFNG antibody

Three mammalian fringe family members, namely Manic Fringe, Radical Fringe and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Lunatic Fringe, also known as LFNG or SCDO3, is a 379 amino acid single-pass type II membrane protein that localizes to the membrane of the Golgi apparatus. Functioning as a glycosyltransferase, Lunatic Fringe acts a critical mediator of somite patterning and segmentation and plays a fundamental role in initiating the elongation of O-linked fucose residues that are attached to Notch molecules. Defects in the gene encoding Lunatic Fringe are the cause of autosomal recessive spondylocostal dysostosis 3 (SCDO3), a disorder that arises during embryonic development and is characterized by rib anomalies and multiple vertebrate segmentation. Three isoforms of Lunatic Fringe are expressed due to alternative splicing events.

General readings

Dunwoodie, S.L. Biochim. Biophys. Acta 1792(2):100-111(2009)
Reedijk, M., et al. Int. J. Oncol. 33(6):1223-1229(2008)
Sparrow, D.B., et al. Am. J. Hum. Genet. 78(1):28-37(2006)
Cole, S.E., et al. Dev. Cell 3(1):75-84(2002)
Moran, J.L., et al. Mamm. Genome 10(6):535-541(1999)

Items 1 to 20 of 27 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LFNG antibody

Western blot analysis of extracts from MCF-7 cells and HUVEC cells, using LFNG antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LFNG antibody

WB Suggested Anti-LFNG Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Muscle Rabbit IgG Purified Eq, GP, Hu, Ms, Por, Rt, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

LFNG (Center) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded skeletal muscle reacted with LFNG Antibody (Center) Cat.-No AP52467PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

LFNG antibody

LFNG Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

LFNG antibody

Western Blot analysis of LFNG expression in transfected 293T cell line (H00003955-T01) by LFNG MaxPab polyclonal antibody.

Lane 1: LFNG transfected lysate(27.5 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

LFNG antibody

Western Blot analysis of LFNG expression in transfected 293T cell line (H00003955-T01) by LFNG MaxPab polyclonal antibody.

Lane 1: LFNG transfected lysate(28.20 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

LFNG antibody

Immunofluorescence of monoclonal antibody to LFNG on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG1 2D10-3C11 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

LFNG antibody

LFNG monoclonal antibody (M03), clone 1F9 Western Blot analysis of LFNG expression in NIH/3T3 ( Cat # L018V1 ). Mouse IgG2a 1F9 Purified Hu, Ms E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

LFNG antibody

Western Blot analysis of LFNG expression in transfected 293T cell line by LFNG monoclonal antibody (M05), clone 3C4.

Lane 1: LFNG transfected lysate(28.2 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2b 3C4 Purified Hu E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

LFNG antibody

LFNG Mouse IgG2b 3C4 Ascites Hu E
0.2 ml / €370.00
  Abnova Taiwan Corp.

LFNG antibody

LFNG monoclonal antibody (M06), clone 3D12 Western Blot analysis of LFNG expression in PC-12 ( Cat # L012V1 ). Mouse IgG2a 3D12 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

LFNG antibody

LFNG Mouse IgG2b 4F8 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

LFNG antibody

LFNG monoclonal antibody (M11), clone 1B6. Western Blot analysis of LFNG expression in human pancreas. Mouse IgG2a 1B6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

LFNG antibody

LFNG Mouse IgG2b 3D7 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

LFNG antibody

LFNG Mouse IgG2b 3B5 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

LFNG antibody

LFNG Mouse IgG2a 2G9 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

LFNG antibody

Western blot analysis of extracts from HuvEc/MCF-7 cells, using LFNG Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

LFNG antibody

Western blot analysis of extracts from HuvEc/MCF-7 cells, using LFNG Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

LFNG antibody

Human Muscle; WB Suggested Anti-LFNG Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Muscle; LFNG antibody - N-terminal region (ARP44923_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

LFNG antibody

Western Blot: Lunatic Fringe Antibody [NBP1-59432] - This Anti-LFNG antibody was used in Western Blot of Fetal Muscle tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Items 1 to 20 of 27 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn