LIFR / CD118 antibody

Principal name

LIFR / CD118 antibody

Alternative names for LIFR / CD118 antibody

LIFR, Leukemia inhibitory factor receptor, LIF receptor, LIF-R, CD118

SwissProt ID

O70535 (Rat), P42702 (Human), P42703 (Mouse), Q5XNR9 (Canfa)

Gene ID

3977 (LIFR), 16880 (Lifr), 81680

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of LIFR / CD118 antibody

LIFR, also known as CD118(Cluster of Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. This gene encodes a protein that belongs to the type I cytokine receptor family. It is mapped to 5p31.1. The LIF receptor(LIFR) is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of the leukemia-inhibitory factor. LIF is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, togerther with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland.

General readings

Gearing DP., et al. (1991) EMBO J. 10:2839-2848.Cheng JG., et al. (2001) Proc Nati Acad Sci USA 98:8680-8685.

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LIFR / CD118 antibody

  Anti-LIFR Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, nucleus. Positive control: Human colon and ovarian cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human colon and ovarian cancer tissue using LIFR antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

LIFR - human gene knockout kit via CRISPR

LIFR - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

LIFR - human gene knockout kit via CRISPR

LIFR - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

LIFR - human gene knockout kit via CRISPR

LIFR - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

LIFR - human gene knockout kit via CRISPR

LIFR - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lifr - mouse gene knockout kit via CRISPR

Lifr - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Lifr - mouse gene knockout kit via CRISPR

Lifr - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lifr - mouse gene knockout kit via CRISPR

Lifr - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lifr - mouse gene knockout kit via CRISPR

Lifr - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

LIFR / CD118 (45-833, His-tag)

LIFR / CD118 Human Purified > 90 % by SDS - PAGE
0.25 mg / €940.00
  Acris Antibodies GmbH

LIFR / CD118 (45-833, His-tag)

LIFR / CD118 Human Purified > 90 % by SDS - PAGE
50 µg / €300.00
  Acris Antibodies GmbH

ELISA Kits

Catalog No.    

Human LIFR ELISA Kit

Human LIFR ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

LIFR overexpression lysate

LIFR overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Lifr (GFP-tagged) - Mouse leukemia inhibitory factor receptor (Lifr), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Lifr (GFP-tagged) - Mouse leukemia inhibitory factor receptor (Lifr), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,900.00
  OriGene Technologies, Inc.

Lenti ORF particles, Lifr (GFP-tagged) - Mouse leukemia inhibitory factor receptor (Lifr), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Lifr (GFP-tagged) - Mouse leukemia inhibitory factor receptor (Lifr), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,400.00
  OriGene Technologies, Inc.

Lenti ORF particles, Lifr (Myc-DDK-tagged) - Mouse leukemia inhibitory factor receptor (Lifr), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Lifr (Myc-DDK-tagged) - Mouse leukemia inhibitory factor receptor (Lifr), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,710.00
  OriGene Technologies, Inc.

Lenti ORF particles, Lifr (Myc-DDK-tagged) - Mouse leukemia inhibitory factor receptor (Lifr), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Lifr (Myc-DDK-tagged) - Mouse leukemia inhibitory factor receptor (Lifr), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,260.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Lifr (GFP-tagged ORF) - Rat leukemia inhibitory factor receptor alpha (Lifr), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lifr (GFP-tagged ORF) - Rat leukemia inhibitory factor receptor alpha (Lifr), 200 uL, >10^7 TU/mL  
200 µl / €2,260.00
  OriGene Technologies, Inc.

Lenti ORF particles, Lifr (Myc-DDK-tagged ORF) - Rat leukemia inhibitory factor receptor alpha (Lifr), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lifr (Myc-DDK-tagged ORF) - Rat leukemia inhibitory factor receptor alpha (Lifr), 200 uL, >10^7 TU/mL  
200 µl / €2,041.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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