LINGO1 antibody

Principal name

LINGO1 antibody

Alternative names for LINGO1 antibody

LINGO1, LERN1, LRRN6A, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat and immunoglobilin-domain containing protein 1, Leucine-rich repeat neuronal protein 6A, Leucine-rich repeat neuronal protein 1

SwissProt ID

Q50L44 (Chick), Q96FE5 (Human), Q9D1T0 (Mouse)

Gene ID

84894 (LINGO1), 4584894 (A1DNW0)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Eq (Equine), Xen (Xenopus)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of LINGO1 antibody

Lingo1 also known as Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein1. LINGO-1 is primarily expressed in neuronal tissue, and most abundantly in cortex. It has been implicated in the inhibition of axon regeneration through a ternary complex formed with NgR1 (ligand-binding subunit) and p75 (signal transducing subunit). The inhibitory action is achieved through RhoA-GTP upregulation in response to the presence of MOG, MAG or Nogo-66 in the central nervous system. LINGO-1 also inhibits oligodendrocyte precursor differentiation and myelination, by a mechanism that also involves activation of RhoA, but which apparently does not require 75 or NgR1.Recombinant human LINGO1 protein, was expressed in E.coli

General readings

Mi S., et al (2004). Nat. Neurosci. 7:221-228.Mi S., et al (2005). Nat. Neurosci. 8:745-751.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LINGO1 (N-term) antibody

Western blot analysis of LINGO1 (arrow) using rabbit polyclonal LINGO1 Antibody (N-term) (Cat.#TA302273).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LINGO1 gene (Lane 2) (Origene Technologies). Rabbit Ig Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LINGO1 antibody

LINGO1 Rabbit Purified Chk, Hu
50 µg / €379.00
  OriGene Technologies, Inc.

LINGO1 antibody

Anti-LINGO1 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Eq, Hu, Xen
50 µg / €379.00
  OriGene Technologies, Inc.

LINGO1 antibody

Anti-LINGO1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

LINGO1 antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with LINGO1 polyclonal antibody ( Cat # PAB2857 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

LINGO1 antibody

LINGO1 Rabbit Hu P
50 µl / €440.00
  Novus Biologicals Inc.

LINGO1 antibody

LINGO1 Rabbit Purified Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

LINGO1 antibody

Immunohistochemistry-Paraffin: Lingo1 Antibody [NBP1-83686] - Immunohistochemical staining of human tonsil shows moderate positivity in reaction center cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

LINGO1

LINGO1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

LINGO1 (241-370, His-tag)

LINGO1 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

LINGO1 (241-370, His-tag)

LINGO1 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

LINGO1

LINGO1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

LINGO1

LINGO1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

LINGO1 overexpression lysate

LINGO1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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