LIPA antibody

Principal name

LIPA antibody

Alternative names for LIPA antibody

LIPA, Lysosomal acid lipase/cholesteryl ester hydrolase, LAL, Acid cholesteryl ester hydrolase, EC=3.1.1.13, Sterol esterase, Lipase A, Cholesteryl esterase

SwissProt ID

P38571 (Human), Q64194 (Rat), Q9Z0M5 (Mouse)

Gene ID

3988 (LIPA)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), Por (Porcine), Rb (Rabbit), Sh (Sheep)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of LIPA antibody

Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LIPA antibody

  Rabbit Polyclonal Lipase A Antibody  
Western Blot: Lysosomal acid lipase Antibody - WB detection of LIPA in HepG2 whole cell extract. Rabbit Purified Hu, Ms C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LIPA antibody

  Rabbit Polyclonal Anti-LIPA Antibody  
Host:Rabbit; Target Name:LIPA; Sample Tissue:Human Fetal Heart; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Eq, Hu, Por, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

LIPA antibody

Western blot analysis using LAL mouse mAb against LAL recombinant protein. Mouse IgG2a 9G7F12 Purified Hu E, WB
0.1 ml / €360.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

LIPA (transcript variant 2)

  Recombinant protein of human lipase A, lysosomal acid, cholesterol esterase (LIPA), transcript variant 2  
LIPA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

LIPA overexpression lysate

LIPA overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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