LMAN1 / ERGIC53 antibody

Principal name

LMAN1 / ERGIC53 antibody

Alternative names for LMAN1 / ERGIC53 antibody

ERGIC-53, F5F8D, Lectin mannose-binding 1, Gp58, ER-Golgi intermediate compartment 53 kDa protein, Intracellular mannose-specific lectin MR60

SwissProt ID

P49257 (Human), Q62902 (Rat), Q9D0F3 (Mouse), Q9UQG6 (Human)

Gene ID

3998 (LMAN1), 70361 (Lman1), 116666

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Dros (Drosophila), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Paraffin Sections (P)

Background of LMAN1 / ERGIC53 antibody

LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

General readings

Neve,E.P., (2005) J. Mol. Biol. 354 (3), 556-568

  1. Quick-Filters:
  2. Highly Validated (4)

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LMAN1 / ERGIC53 antibody

  LMAN1 mouse monoclonal antibody, clone OTI1A8 (formerly 1A8)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502137) Mouse IgG1 OTI1A8 Purified Can, Hu, Mky, Rt F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

LMAN1 / ERGIC53 antibody

  Rabbit Polyclonal Anti-LMAN1 Antibody  
WB Suggested Anti-LMAN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

LMAN1 / ERGIC53 antibody

  LMAN1 mouse monoclonal antibody, clone OTI1E3 (formerly 1E3)  
Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502138) Mouse IgG1 OTI1E3 Purified Can, Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LMAN1 / ERGIC53 antibody

  LMAN1 mouse monoclonal antibody, clone OTI1C5 (formerly 1C5)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502237) Mouse IgG1 OTI1C5 Purified Hu, Mky F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LMAN1 / ERGIC53 antibody

  Rabbit Polyclonal Anti-LMAN1 Antibody  
WB Suggested Anti-LMAN1 Antibody Titration: 1.25 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LMAN1 / ERGIC53 antibody

  LMAN1 mouse monoclonal antibody, clone OTI2B10 (formerly 2B10)  
Anti-LMAN1 mouse monoclonal antibody (TA502110) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LMAN1(RC207088). Mouse IgG1 OTI2B10 Purified Hu, Mky ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LMAN1 / ERGIC53 antibody

  LMAN1 mouse monoclonal antibody, clone OTI1B8 (formerly 1B8)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMAN1 (RC207088, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LMAN1. Mouse IgG1 OTI1B8 Purified Can, Hu, Mky, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CRISPR

Catalog No. Species Donor Vector  

LMAN1 - human gene knockout kit via CRISPR

LMAN1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

LMAN1 - human gene knockout kit via CRISPR

LMAN1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

LMAN1 - human gene knockout kit via CRISPR

LMAN1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

LMAN1 - human gene knockout kit via CRISPR

LMAN1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lman1 - mouse gene knockout kit via CRISPR

Lman1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Lman1 - mouse gene knockout kit via CRISPR

Lman1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lman1 - mouse gene knockout kit via CRISPR

Lman1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lman1 - mouse gene knockout kit via CRISPR

Lman1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

LMAN1 / ERGIC53

  Recombinant protein of human lectin, mannose-binding, 1 (LMAN1)  
LMAN1 / ERGIC53 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, LMAN1 (mGFP-tagged) - Human lectin, mannose-binding, 1 (LMAN1), 200 uL, >10^7 TU/mL

Lenti ORF particles, LMAN1 (mGFP-tagged) - Human lectin, mannose-binding, 1 (LMAN1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, LMAN1 (Myc-DDK tagged) - Human lectin, mannose-binding, 1 (LMAN1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, LMAN1 (Myc-DDK tagged) - Human lectin, mannose-binding, 1 (LMAN1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Lman1 (GFP-tagged) - Mouse lectin, mannose-binding, 1 (Lman1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Lman1 (GFP-tagged) - Mouse lectin, mannose-binding, 1 (Lman1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,140.00
  OriGene Technologies, Inc.

Lenti ORF particles, Lman1 (GFP-tagged) - Mouse lectin, mannose-binding, 1 (Lman1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Lman1 (GFP-tagged) - Mouse lectin, mannose-binding, 1 (Lman1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,140.00
  OriGene Technologies, Inc.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn