LMAN1 / ERGIC53 antibody

Principal name

LMAN1 / ERGIC53 antibody

Alternative names for LMAN1 / ERGIC53 antibody

ERGIC-53, F5F8D, Lectin mannose-binding 1, Gp58, ER-Golgi intermediate compartment 53 kDa protein, Intracellular mannose-specific lectin MR60

SwissProt ID

P49257 (Human), Q62902 (Rat), Q9D0F3 (Mouse), Q9UQG6 (Human)

Gene ID

3998 (LMAN1)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Dros (Drosophila), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Chicken, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of LMAN1 / ERGIC53 antibody

LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

General readings

Neve,E.P., (2005) J. Mol. Biol. 354 (3), 556-568

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  2. Highly Validated (5)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LMAN1 / ERGIC53 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502137) Mouse IgG1 OTI1A8 Purified Can, Hu, Mky, Rt F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

LMAN1 / ERGIC53 antibody

WB Suggested Anti-LMAN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

LMAN1 / ERGIC53 antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502138) Mouse IgG1 OTI1E3 Purified Can, Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LMAN1 / ERGIC53 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502237) Mouse IgG1 OTI1C5 Purified Hu, Mky F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LMAN1 / ERGIC53 antibody

Hum. Adult Placenta; Host: Rabbit. Target Name: CHAD . Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; LMAN1 antibody - N-terminal region (ARP46613_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Dros, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

LMAN1 / ERGIC53 antibody

WB Suggested Anti-LMAN1 Antibody Titration: 1.25 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LMAN1 / ERGIC53 antibody

Anti-LMAN1 mouse monoclonal antibody (TA502110) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LMAN1(RC207088). Mouse IgG1 OTI2B10 Purified Hu, Mky ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LMAN1 / ERGIC53 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMAN1 (RC207088, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LMAN1. Mouse IgG1 OTI1B8 Purified Can, Hu, Mky, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LMAN1 / ERGIC53 antibody

Human HepG2; WB Suggested Anti-LMAN1 Antibody Titration: 1.25ug/ml. Positive Control: HepG2 cell lysate; LMAN1 antibody - middle region (ARP46614_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

LMAN1 / ERGIC53

LMAN1 / ERGIC53 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

10 Item(s)

per page
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