LMX1A antibody

Principal name

LMX1A antibody

Alternative names for LMX1A antibody

LMX1A, LIM homeobox transcription factor 1-alpha, LIM/homeobox protein LMX1A, LIM/homeobox protein 1.1, LMX-1.1

SwissProt ID

Q04650 (Mesau), Q8TE12 (Human), Q9JKU8 (Mouse)

Gene ID

4009 (LMX1A), 110648 (Lmx1a)

Available reactivities

Can (Canine), Hu (Human), Rt (Rat), Bov (Bovine), Chk (Chicken), Ms (Mouse), Ze (Zebrafish), African clawed frog, Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of LMX1A antibody

Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin. Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-199 AL160058.8 14249-14447 c 200-2447 AK127724.1 362-2609 2448-3382 AL390730.12 9415-10349 c

General readings

Failli V, Bachy I and Retaux S. Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system. Mech. Dev. 2002; 118:225-8.
Nakatani T, Kumai M, Mizuhara E, et al. Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon. Dev. Biol. 2010; 339:101-13.
Chizhikov VV and Millen KJ. Control of roof plate formation by LMX1A in the developing spinal cord. Development 2004; 131:2693-705.
Lin CK, Chao TK, Lai HC, et al. LMX1A as a prognostic marker in ovarian mucinous cystadenocarcinoma. Am. J. Clin. Pathol. 2012; 137:971-7.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LMX1A antibody

  Rabbit Polyclonal Anti-LMX1A Antibody  
WB Suggested Anti-LMX1A Antibody; Titration: 1 ug/ml; Positive Control: 721_B Whole Cell Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

LMX1A antibody

  Rabbit Polyclonal Anti-LMX1A Antibody  
WB Suggested Anti-LMX1A Antibody Titration: 0.3125ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LMX1A (C-term) antibody

  Rabbit Polyclonal LMX1A Antibody  
Western blot analysis of LMX1A in rat brain tissue lysate with LMX1A antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LMX1A antibody

  Rabbit Polyclonal Anti-Lmx1a Antibody  
WB Suggested Anti-Lmx1a Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Mouse Small Intestine Rabbit IgG Purified Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

LMX1A antibody

  Rabbit Polyclonal Anti-LMX1A Antibody  
WB Suggested Anti-LMX1A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

LMX1A antibody

Western blot analysis of anti-Lmx1a (AP11391PU-N) in HL60 cell line lysates (35 µg/lane). Lmx1a (arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

LMX1A - human gene knockout kit via CRISPR

LMX1A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

LMX1A - human gene knockout kit via CRISPR

LMX1A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

LMX1A - human gene knockout kit via CRISPR

LMX1A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

LMX1A - human gene knockout kit via CRISPR

LMX1A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmx1a - mouse gene knockout kit via CRISPR

Lmx1a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Lmx1a - mouse gene knockout kit via CRISPR

Lmx1a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmx1a - mouse gene knockout kit via CRISPR

Lmx1a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmx1a - mouse gene knockout kit via CRISPR

Lmx1a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

LMX1A overexpression lysate

LMX1A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

LMX1A overexpression lysate

LMX1A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, LMX1A (mGFP-tagged) - Human LIM homeobox transcription factor 1, alpha (LMX1A), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, LMX1A (mGFP-tagged) - Human LIM homeobox transcription factor 1, alpha (LMX1A), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, LMX1A (Myc-DDK tagged) - Human LIM homeobox transcription factor 1, alpha (LMX1A), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, LMX1A (Myc-DDK tagged) - Human LIM homeobox transcription factor 1, alpha (LMX1A), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Lmx1a (GFP-tagged) - Mouse LIM homeobox transcription factor 1 alpha (Lmx1a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lmx1a (GFP-tagged) - Mouse LIM homeobox transcription factor 1 alpha (Lmx1a), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Lmx1a (Myc-DDK-tagged) - Mouse LIM homeobox transcription factor 1 alpha (Lmx1a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lmx1a (Myc-DDK-tagged) - Mouse LIM homeobox transcription factor 1 alpha (Lmx1a), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

20 Item(s)

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