LMX1A antibody

Principal name

LMX1A antibody

Alternative names for LMX1A antibody

LMX1A, LIM homeobox transcription factor 1-alpha, LIM/homeobox protein LMX1A, LIM/homeobox protein 1.1, LMX-1.1

SwissProt ID

Q04650 (Mesau), Q8TE12 (Human), Q9JKU8 (Mouse)

Gene ID

4009 (LMX1A), 110648 (Lmx1a)

Available reactivities

Can (Canine), Hu (Human), Rt (Rat), Bov (Bovine), Chk (Chicken), Ms (Mouse), Ze (Zebrafish), African clawed frog, Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of LMX1A antibody

Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin. Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-199 AL160058.8 14249-14447 c 200-2447 AK127724.1 362-2609 2448-3382 AL390730.12 9415-10349 c

General readings

Failli V, Bachy I and Retaux S. Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system. Mech. Dev. 2002; 118:225-8.
Nakatani T, Kumai M, Mizuhara E, et al. Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon. Dev. Biol. 2010; 339:101-13.
Chizhikov VV and Millen KJ. Control of roof plate formation by LMX1A in the developing spinal cord. Development 2004; 131:2693-705.
Lin CK, Chao TK, Lai HC, et al. LMX1A as a prognostic marker in ovarian mucinous cystadenocarcinoma. Am. J. Clin. Pathol. 2012; 137:971-7.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LMX1A antibody

  Rabbit Polyclonal Anti-LMX1A Antibody  
WB Suggested Anti-LMX1A Antibody; Titration: 1 ug/ml; Positive Control: 721_B Whole Cell Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

LMX1A antibody

  Rabbit Polyclonal Anti-LMX1A Antibody  
WB Suggested Anti-LMX1A Antibody Titration: 0.3125ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LMX1A antibody

Human Skeletal muscle; Rabbit Anti-LMX1A Antibody. Catalog Number: ARP31999. Paraffin Embedded Tissue: Human Muscle. Cellular Data: Skeletal muscle cells. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; LMX1A antibody - middle region (ARP31999_P050) in Human Skeletal muscle cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze
50 µg / €350.00
  AVIVA Systems Biology

LMX1A antibody

Human Muscle; Rabbit Anti-LMX1A Antibody. Catalog Number: ARP31999. Paraffin Embedded Tissue: Human Muscle. Cellular Data: Skeletal muscle cells. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; LMX1A antibody - middle region (ARP31999_T100) in Human Muscle cells using Immunohistochemistry Rabbit Aff - Purified Can, Hu, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

LMX1A antibody

  Rabbit polyclonal anti-LMX1A antibody (CT)  
Western blot analysis of LMX1A in rat brain tissue lysate with LMX1A antibody at (A) 1 and (B) 2 µg/mL. Rabbit Purified Hu, Ms, Rt E, WB
0.1 mg / €345.00
  OriGene Technologies, Inc.

LMX1A (C-term) antibody

  Rabbit Polyclonal LMX1A Antibody  
Western blot analysis of LMX1A in rat brain tissue lysate with LMX1A antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LMX1A antibody

  Rabbit Polyclonal Anti-Lmx1a Antibody  
WB Suggested Anti-Lmx1a Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Mouse Small Intestine Rabbit IgG Purified Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

LMX1A antibody

  Rabbit Polyclonal Anti-LMX1A Antibody  
WB Suggested Anti-LMX1A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

LMX1A antibody

Western blot analysis of anti-Lmx1a (AP11391PU-N) in HL60 cell line lysates (35 µg/lane). Lmx1a (arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

LMX1A antibody

Western blot analysis of Lmx1a polyclonal antibody ( Cat # PAB3071 ) in HL-60 cell line lysates ( 35 µg/lane ) . Lmx1a ( arrow ) was detected using the purified polyclonal antibody ( 1 : 60 dilution ) . Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

LMX1A antibody

Human Brain; WB Suggested Anti-LMX1A Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: Human brain; LMX1A antibody - N-terminal region (ARP32673_P050) in Human Brain cells using Western Blot Rabbit Aff - Purified Hu, Ms, Por WB
50 µg / €350.00
  AVIVA Systems Biology

LMX1A (Center) antibody

Mouse Small Intestine; WB Suggested Anti-Lmx1a Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: Mouse Small Intestine; Lmx1a antibody - middle region (ARP37428_P050) in Mouse Small Intestine cells using Western Blot Rabbit Aff - Purified Ms WB
50 µg / €350.00
  AVIVA Systems Biology

LMX1A antibody

Mouse SP2/0; WB Suggested Anti-LMX1A Antibody Titration: 5.0ug/ml. Positive Control: SP2/0 cell lysate; LMX1A antibody - C-terminal region (ARP37928_T100) in Mouse SP2/0 cells using Western Blot Rabbit Aff - Purified Chk, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

LMX1A - human gene knockout kit via CRISPR

LMX1A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

LMX1A - human gene knockout kit via CRISPR

LMX1A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

LMX1A - human gene knockout kit via CRISPR

LMX1A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

LMX1A - human gene knockout kit via CRISPR

LMX1A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmx1a - mouse gene knockout kit via CRISPR

Lmx1a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Lmx1a - mouse gene knockout kit via CRISPR

Lmx1a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lmx1a - mouse gene knockout kit via CRISPR

Lmx1a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

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