LPIN1 / Lipin-1 antibody

Principal name

LPIN1 / Lipin-1 antibody

Alternative names for LPIN1 / Lipin-1 antibody

KIAA0188, Phosphatidate phosphatase LPIN1

SwissProt ID

Q14693 (Human), Q91ZP3 (Mouse)

Gene ID

23175 (LPIN1), 14245 (Lpin1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rt (Rat), Ze (Zebrafish), Eq (Equine), Rb (Rabbit)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of LPIN1 / Lipin-1 antibody

The Lipin family of nuclear proteins contains three members: Lipin-1, Lipin-2 and Lipin-3, all of which contain a nuclear sigl sequence, a highly conserved amino-termil (NLIP) domain and a carboxy-termil (CLIP) domain. LPIN1 (Lipin-1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC-1á target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARá. LPIN1 also ictivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.

General readings

Ong,K.L., (2008) Am. J. Hypertens. 21 (5), 539-545

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LPIN1 / Lipin-1 antibody

  LPIN1 mouse monoclonal antibody, clone OTI8F10 (formerly 8F10)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805972) Mouse IgG1 OTI8F10 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

  LPIN1 mouse monoclonal antibody, clone OTI1B7 (formerly 1B7)  
Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805973) Mouse IgG1 OTI1B7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

  LPIN1 mouse monoclonal antibody, clone OTI7F5 (formerly 7F5)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA806141)(1:150) Mouse IgG2a OTI7F5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

  LPIN1 mouse monoclonal antibody, clone OTI4C11 (formerly 4C11)  
Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806417) Mouse IgG2b OTI4C11 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

  LPIN1 mouse monoclonal antibody, clone OTI7H6 (formerly 7H6)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA806418) Dilution: 1:150 Mouse IgG1 OTI7H6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

  LPIN1 mouse monoclonal antibody, clone OTI5H2 (formerly 5H2)  
Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA806419) Dilution: 1:150 Mouse IgG2a OTI5H2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

  LPIN1 mouse monoclonal antibody, clone OTI5B5 (formerly 5B5)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA806467) Dilution: 1:150 Mouse IgG1 OTI5B5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

  Rabbit Polyclonal Antibody against LPIN1  
Detection of LPIN1 in 3T3 L1 lysate Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LPIN1 / Lipin-1 antibody

  Rabbit Polyclonal Antibody against LPIN1  
Detection of LPIN1 in 3T3 L1 lysate Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LPIN1 / Lipin-1 antibody

  Rabbit Polyclonal LPIN1 Antibody  
Western blot analysis of LPIN1 in K562 cell lysate with LPIN1 antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LPIN1 / Lipin-1 antibody

  Rabbit Polyclonal Anti-LPIN1 Antibody  
WB Suggested Anti-LPIN1 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysateLPIN1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt ICC/IF, WB
50 µg / €325.00
  OriGene Technologies, Inc.

LPIN1 / Lipin-1 antibody

  LPIN1 mouse monoclonal antibody, clone OTI2H6 (formerly 2H6)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806186) Mouse IgG1 OTI2H6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

  LPIN1 mouse monoclonal antibody, clone OTI1B2 (formerly 1B2)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-LPIN1 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA806208)(1:150) Mouse IgG1 OTI1B2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

  LPIN1 mouse monoclonal antibody, clone OTI2C8 (formerly 2C8)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LPIN1 (RC207138, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LPIN1.(1:2000) Mouse IgG1 OTI2C8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CRISPR

Catalog No. Species Donor Vector  

LPIN1 - human gene knockout kit via CRISPR

LPIN1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

LPIN1 - human gene knockout kit via CRISPR

LPIN1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

LPIN1 - human gene knockout kit via CRISPR

LPIN1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

LPIN1 - human gene knockout kit via CRISPR

LPIN1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lpin1 - mouse gene knockout kit via CRISPR

Lpin1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Lpin1 - mouse gene knockout kit via CRISPR

Lpin1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

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