LPIN1 / Lipin-1 antibody

Principal name

LPIN1 / Lipin-1 antibody

Alternative names for LPIN1 / Lipin-1 antibody

KIAA0188, Phosphatidate phosphatase LPIN1

SwissProt ID

Q14693 (Human), Q91ZP3 (Mouse)

Gene ID

23175 (LPIN1), 14245 (Lpin1)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Ze (Zebrafish), Eq (Equine), Rb (Rabbit)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Immunoprecipitation (IP), Frozen Sections (C)

Background of LPIN1 / Lipin-1 antibody

Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.

General readings

Ong,K.L., (2008) Am. J. Hypertens. 21 (5), 539-545

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LPIN1 / Lipin-1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805972) Mouse IgG1 OTI8F10 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805973) Mouse IgG1 OTI1B7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA806141)(1:150) Mouse IgG2a OTI7F5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806417) Mouse IgG2b OTI4C11 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA806418) Dilution: 1:150 Mouse IgG1 OTI7H6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA806419) Dilution: 1:150 Mouse IgG2a OTI5H2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA806467) Dilution: 1:150 Mouse IgG1 OTI5B5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

Immunohistochemistry: LPIN1 Antibody (EPR3725) [NBP1-40784] - Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-Lipin1 Rabbit IgG EPR3725 Hu F, ICC/IF, IP, P, WB
0.1 ml / €480.00
  Novus Biologicals Inc.

LPIN1 / Lipin-1 antibody

Detection of LPIN1 in 3T3 L1 lysate Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LPIN1 / Lipin-1 antibody

Detection of LPIN1 in 3T3 L1 lysate Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LPIN1 / Lipin-1 antibody

Western blot analysis of LPIN1 in K562 cell lysate with LPIN1 antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LPIN1 / Lipin-1 antibody

WB Suggested Anti-LPIN1 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysateLPIN1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt ICC/IF, WB
50 µg / €325.00
  OriGene Technologies, Inc.

LPIN1 / Lipin-1 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-LPIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806186) Mouse IgG1 OTI2H6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-LPIN1 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA806208)(1:150) Mouse IgG1 OTI1B2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LPIN1 (RC207138, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LPIN1.(1:2000) Mouse IgG1 OTI2C8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LPIN1 / Lipin-1 antibody

LPIN1 / Lipin-1 Mouse IgG2a 3D9 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

LPIN1 / Lipin-1 antibody

LPIN1 / Lipin-1 Goat Hu, Ms E
0.1 mg / €390.00
  Abnova Taiwan Corp.

LPIN1 / Lipin-1 antibody

Western blot analysis of LPIN1 in 3T3-L1 lysate using LPIN1 polyclonal antibody ( Cat # PAB12399 ). Rabbit Hu, Ms, Rt C, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

LPIN1 / Lipin-1 antibody

Western blot analysis of LPIN1 in 3T3-L1 lysate using LPIN1 polyclonal antibody ( Cat # PAB12400 ). Rabbit Hu, Ms, Rt WB
0.1 ml / €400.00
  Abnova Taiwan Corp.

LPIN1 / Lipin-1 antibody

Human Pineal Tissue; Rabbit Anti-LPIN1 Antibody . Catalog Number: ARP53826_P050 . Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue . Observed Staining: Cytoplasmic and membrane in cell bodies and processes of pinealocytes . Primary Antibody Concentration: 1:100 . Other Working Concentrations: 1/600 . Secondary Antibody: Donkey anti-Rabbit-Cy3 . Secondary Antibody Concentration: 1:200 . Magnification: 20X . Exposure Time: 0.5 - 2.0 sec .; Rabbit Anti-LPIN1 Antibody (ARP53826_P050) ) in Human Pineal Tissue using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

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