LRP5 antibody

Principal name

LRP5 antibody

Alternative names for LRP5 antibody

LRP7, LRP-5, Low-density lipoprotein receptor-related protein 5

SwissProt ID

O75197 (Human), Q91VN0 (Mouse)

Gene ID

4041 (LRP5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Flow Cytometry (F)

Background of LRP5 antibody

Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration. Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes. All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Lee, D.Y., et al. Menopause 17(5):1064-1070(2010)
Liu, J.M., et al. J. Clin. Endocrinol. Metab. 95 (9), E112-E120 (2010)
Paternoster, L., et al. J. Clin. Endocrinol. Metab. 95(8):3940-3948(2010)
Stathopoulou, M.G., et al. J Am Diet Assoc 110(7):1078-1083(2010)

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LRP5 antibody

  Goat Anti-LRP5 Antibody  
TA305828 (1ug/ml) staining of paraffin embedded Human Pancreas shows staining of cytoplasm in some cells of the islets of Langerhans. Goat Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

LRP5 antibody

  Anti-LRP5 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, nucleus. Positive control: Human colon and ovarian cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human colon and ovarian cancer tissue using LRP5 antibody at dilution 1/55, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

LRP5 antibody

  Anti-LRP5 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, nucleus. Positive control: Human ovarian cancer tissue. Recommended dilution: 1/100-300  The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using LRP5 antibody at dilution 1/115, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

LRP5 antibody

Western blot analysis using LRP5 antibody Cat.-No AM06765PU-N against Human LRP5 (AA: 1422-1615) recombinant protein. (Expected MW is 20.8 kDa Mouse IgG1 2B11 Purified Hu E, F, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

LRP5 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

LRP5 (C-term) antibody

Western blot analysis of LRP5 Antibody (C-term) Cat.-No AP52526PU-N in mouse lung tissue lysates (35ug/lane). This demonstrates the LRP5 antibody detected the LRP5 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

LRP5 - human gene knockout kit via CRISPR

LRP5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

LRP5 - human gene knockout kit via CRISPR

LRP5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

LRP5 - human gene knockout kit via CRISPR

LRP5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

LRP5 - human gene knockout kit via CRISPR

LRP5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, LRP5 (mGFP-tagged) - Human low density lipoprotein receptor-related protein 5 (LRP5), 200 uL, >10^7 TU/mL

Lenti ORF particles, LRP5 (mGFP-tagged) - Human low density lipoprotein receptor-related protein 5 (LRP5), 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, LRP5 (Myc-DDK tagged) - Human low density lipoprotein receptor-related protein 5 (LRP5) , 200 uL, >10^7 TU/mL

Lenti ORF particles, LRP5 (Myc-DDK tagged) - Human low density lipoprotein receptor-related protein 5 (LRP5) , 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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