LRP5 antibody

Principal name

LRP5 antibody

Alternative names for LRP5 antibody

LRP7, LRP-5, Low-density lipoprotein receptor-related protein 5

SwissProt ID

O75197 (Human), Q91VN0 (Mouse)

Gene ID

4041 (LRP5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Dot blot (Dot), Flow Cytometry (F), Frozen Sections (C)

Background of LRP5 antibody

Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration. Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes. All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family.

General readings

Nature. 2005 Dec 8;438(7069):867-72.
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction.
Davidson G, Wu W, Shen J, Bilic J, Fenger U, Stannek P, Glinka A, Niehrs C.
Division of Molecular Embryology, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. g.davidson@dkfz-heidelberg.de

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LRP5 antibody

TA305828 (1ug/ml) staining of paraffin embedded Human Pancreas shows staining of cytoplasm in some cells of the islets of Langerhans. Goat Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

LRP5 antibody

Predicted cell location: Cytoplasm, nucleus. Positive control: Human colon and ovarian cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human colon and ovarian cancer tissue using LRP5 antibody at dilution 1/55, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

LRP5 antibody

Predicted cell location: Cytoplasm, nucleus. Positive control: Human ovarian cancer tissue. Recommended dilution: 1/100-300  The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using LRP5 antibody at dilution 1/115, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

LRP5 antibody

Western blot analysis using LRP5 antibody Cat.-No AM06765PU-N against Human LRP5 (AA: 1422-1615) recombinant protein. (Expected MW is 20.8 kDa Mouse IgG1 2B11 Purified Hu E, F, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

LRP5 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

LRP5 (C-term) antibody

Western blot analysis of LRP5 Antibody (C-term) Cat.-No AP52526PU-N in mouse lung tissue lysates (35ug/lane). This demonstrates the LRP5 antibody detected the LRP5 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

LRP5 antibody

LRP5 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

LRP5 antibody

Detection limit for recombinant GST tagged LRP5 is approximately 0.1ng/ml as a capture antibody. Mouse IgG1 1E9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

LRP5 antibody

LRP5 Mouse IgG1 1E9 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

LRP5 antibody

Formalin-fixed and paraffin-embedded human hepatocellular cancer tissue reacted with LRP5 polyclonal antibody ( Cat # PAB1979 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

LRP5 antibody

LRP5 Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

LRP5 antibody

Western blot analysis of LRP5/LRP6 with Jurkat cell lysate ( Lane 1: 100 µg; Lane 2: 50 µg ) . Rabbit Hu, Ms WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

LRP5 pThr1492 antibody

Human colon tissue stained with LRP5 ( phospho T1492 ) polyclonal antibody ( Cat # PAB12631 ) at 1 : 50 for 10 min at RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Rabbit Hu, Ms, Rt E, IP, P, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

LRP5 antibody

The cell lysate derived from NIH/3T3 was immunoprobed by LRP5 polyclonal antibody ( Cat # PAB12699 ) at 1 : 500. An immunoreactive band is observed around ~175 kDa ( 1 ). This band is abolished by pre-incubation with immunizing peptide ( 2 ). Rabbit Hu, Ms, Rt E, IP, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

LRP5 antibody

LRP5 Mouse LRP5-5N-4H7 Purified Hu
50 µg / €640.00
  Funakoshi Co., Ltd.

LRP5 antibody

LRP5 Mouse LRP5-5N-6A2 Purified Hu
50 µg / €640.00
  Funakoshi Co., Ltd.

LRP5 antibody

LRP5 Mouse LRP5-5C-2C11 Purified Hu
50 µg / €640.00
  Funakoshi Co., Ltd.

LRP5 antibody

LRP5 Mouse LRP5-5C-3G5 Purified Hu
50 µg / €640.00
  Funakoshi Co., Ltd.

LRP5 antibody

Immunohistochemistry: LRP5 Antibody [NB100-1886] -  LRP5  Antibody [NB100-1886]- 1µg/ml staining of paraffin embedded Human Pancreas shows staining of cytoplasm in some cells of the islets of Langerhans. Goat IgG Aff - Purified Hu E, P
0.1 mg / €400.00
  Novus Biologicals Inc.

LRP5 antibody

Western Blot: LRP5/6 Antibody [NBP1-45687] - Western blot analysis
of LRP-5/6 with Jurkat
cell lysate (Lane 1: 100
µg; Lane 2: 50 µg). Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €440.00
  Novus Biologicals Inc.

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