LRP6 antibody

Principal name

LRP6 antibody

Alternative names for LRP6 antibody

LRP-6, Low-density lipoprotein receptor-related protein 6

SwissProt ID

O75581 (Human), O88572 (Mouse)

Gene ID

4040 (LRP6)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Rt (Rat), Can (Canine)

Available hosts

Goat, Rabbit, Mouse

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Dot blot (Dot), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of LRP6 antibody

The LRP6 gene encodes a member of the low density lipoprotein receptor (LDLR) gene family, which consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDLR proteins are comprised of the same basic structural motifs: an extracellular domain that contains LDLR binding repeats and EGF repeats with associated spacer domains containing the YWTD motif; a single transmembrane-spanning domain; and a C-terminal cytoplasmic domain that generally contains at least 1 copy of the NPXY motif (Brown et al., 1998 [PubMed 9704021]). LRP6 and LRP5 (MIM 603506) function as coreceptors for WNT (MIM 164820) ligands and thus play a role in WNT signaling, which is important in a wide variety of biologic processes during pre- and postnatal life in invertebrates and vertebrates (Kokubu et al., 2004 [PubMed 15469977]).[supplied by OMIM]

General readings

Tamai K et al. LDL-receptor-related proteins in Wnt signal transduction. Nature 407:530-5 (2000). PubMed: 11029007

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LRP6 (C-term) antibody

Western blot analysis of LRP6 (arrow) using rabbit polyclonal LRP6 Antibody (C-term T1546) (Cat# TA302210). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LRP6 gene (Lane 2) (Origene Technologies). Rabbit Ig Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LRP6 antibody

(4ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Purified Can, Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LRP6 (1546-1560) antibody

Liver: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

LRP6 (Internal) antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Hepatocytes and Bile Duct. Goat Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hst, Hu, Mky, Ms, Pigeon, Prim, Rb, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

LRP6 antibody

LRP6 Mouse IgG2b 1A12 Hu, Ms WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

LRP6 antibody

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with LRP6 polyclonal antibody ( Cat # PAB4736 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

LRP6 pThr1479 antibody

The cell lysate derived from conditioned NIH/3T3 was immunoprobed by LRP6 ( phospho T1479 ) polyclonal antibody ( Cat # PAB12632 ) at 1 : 500. An immunoreactive band is observed around ~ 180kDa ( 1 ). This band is abolished by pre-incubation with immunizing peptide ( 2 ). Rabbit Bov, Hu, Ms, Rt C, Dot, E, IP, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

LRP6 antibody

The cell lysate derived from NIH/3T3 was immunoprobed by LRP6 polyclonal antibody ( Cat # PAB12700 ) at 1 : 500. An immunoreactive band is observed around ~180kDa ( 1 ). This band is abolished by pre-incubation with immunizing peptide ( 2 ). Rabbit Bov, Hu, Ms, Rt E, IP, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

LRP6 antibody

Immunohistochemistry: LRP6 Antibody [NB100-1475] -  LRP6 Antibody [NB100-1475] - NB100-1475 (5ug/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat IgG Aff - Purified Hu E, P
0.1 mg / €400.00
  Novus Biologicals Inc.

LRP6 antibody

Western Blot: LRP6 Antibody [NBP1-33029] - Western blot analysis of LRP6 on Hep G2 lysates using NBP1-33029. Rabbit IgG Hu WB
0.1 mg / €340.00
  Novus Biologicals Inc.

LRP6 antibody

Immunohistochemistry-Paraffin: LRP6 Antibody [NBP1-86345] Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in cells of tubules. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates (Overexpressed)

Catalog No.    

LRP6 overexpression lysate

LRP6 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

12 Item(s)

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