LRRC36 antibody

Principal name

LRRC36 antibody

Alternative names for LRRC36 antibody

RORBP70, ROR gamma-binding protein 70, Leucine-rich repeat-containing protein 36

Gene ID

55282 (LRRC36), 270091 (Lrrc36)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit, Mouse, Rat

Available applications

Western blot / Immunoblot (WB)

Background of LRRC36 antibody

The 4F3-3G8-2B7 monoclol antibody reacts with the D binding domain of human and mouse RORγ protein. RORγ is a member of the retinoic acid-related orphan receptor (ROR) family, which also includes RORalpha and RORbeta. ROR family proteins are ligand-dependent transcription factors that play roles in multiple physiological processes. RORγ is expressed in several tissues, including liver, lung, muscle, heart and kidney. Furthermore, it was discovered that altertive transcription results in the expression of an isoform, RORγt, that is expressed exclusively in cells of the lymphoid compartment, mely CD4+CD8+ thymoyctes, Th17 cells of the periphery and lymphoid tissue inducer (Lti) cells of lymphoid organs.The RORγt isoform differs from ROR by three unique amino acids at the amino terminus. Therefore, the 4F3-3G8-2 antibody will react with both the RORγ and RORγt isoforms. In addition our data suggests that 4F3-3C8-2B7 has greater sensitivity to human RORγ than to mouse RORγ. For detection of mouse RORγ, please use cat. 14-6981.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LRRC36 antibody

Lysates prepared from 293 cells (lane 1) and 293 cells transfected with mouse ROR gamma cDNA (lane 2) or human ROR gamma cDNA (lane 3) under reducing conditions with DTT were resolved by SDS-PAGE then immunoblotted with 4 ug/ml of Anti-Human ROR gamma Purified. Bands were visualized using Anti-Mouse IgG HRP. Mouse 4F3-3C8-2B7 Purified Hu WB
25 µg / €180.00
  OriGene Technologies, Inc.

LRRC36 antibody

Left:  Mouse thymus (left) and spleen (right) nuclear cell lysates were loaded at 1x105 cells/lane, probed with 2 ug/mL of Anti-Mouse ROR gamma (t) Purified and revealed with Anti-Rat IgG HRP. Right:  Untransfected (left) and mouse ROR gamma-transfected (right) 293T nuclear cell lysates were loaded at 1x105 cells/lane, probed with 2 ug/ml of Anti-Mouse ROR gamma (t) Purified and revealed with HRP anti-rat IgG. Rat B2D Purified Ms WB
25 µg / €180.00
  OriGene Technologies, Inc.

LRRC36 antibody

Host: Rabbit; Target Name: LRRC36; Sample Tissue: Placenta lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

LRRC36 (N-term) antibody

Western blot analysis of LRRC36 Antibody (N-term) Cat.-No AP52533PU-N in mouse heart tissue lysates (35ug/lane). This demonstrates the LRRC36 antibody detected the LRRC36 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

LRRC36 overexpression lysate

LRRC36 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

5 Item(s)

per page
  • LinkedIn