LTB4R / BLTR antibody

Principal name

LTB4R / BLTR antibody

Alternative names for LTB4R / BLTR antibody

LTB4-R 1, P2Y purinoceptor 7, BLT, BLT1, CMKRL1, GPR16, P2RY7, P2Y7, Leukotriene B4 receptor 1, Chemoattractant receptor-like 1, G-protein coupled receptor 16

SwissProt ID

Q15722 (Human)

Gene ID

1241 (LTB4R)

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Eq (Equine), Mky (Monkey), Ms (Mouse), Op (Opossum), Rb (Rabbit), Hst (Hamster)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Flow Cytometry (F), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of LTB4R / BLTR antibody

Leukotrienes (LTs) are lipid mediators prominently exerting proinflammatory responses. They are divided in two classes: cysteinyl LTs (cysLTs) which have a thioester linkage and LTB4. LTB4, a chemoattractant plays a prominent role in the recruitment and activation of leukocytes. LTB4 acts through two receptors which belong to the G-protein coupled receptor superfamily: BLT1 and BLT2. BLT1 displays high affinity for LTB4 and is highly expressed in leukocytes including granulocytes, macrophages, mast cells, dendritic cells and effector T cells and is expressed to much lower levels in spleen, thymus, heart, skeletal muscle brain and liver. BLT2 on the other hand is a low affinity receptor which does not display selectivity towards LTB4. Its expression is much more ubiquitous than that of BLT1. It is expressed in most human tissues, with the highest expression being in spleen, liver, ovary, and leukocytes. The two receptors could couple and activate different G-proteins, depending on the cell type and the cellular events activating the receptors. However, activation of BLT1 ususally correlates with increasing intracellular concentrations of Ca2+. The LTB4/BLT1 system is involved in many allergic reactions as well as asthma induced as an allergic response, where it plays a significant role in recruiting neutrophils and effector T cells into lungs, as part of an inflammatory response induced by allergens.

General readings

General / background references:Pettersson A et al. First-generation monoclonal antibodies identifying the human leukotriene B(4) receptor-1. Biochem Biophys Res Commun 279:520-5 (2000). PubMed PMID: 11118319

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LTB4R / BLTR antibody

Immunohistochemistry-Paraffin: Leukotriene B4 Receptor 1 Antibody [NBP1-46438] - Rat spinal cord (free floating sections) using Rabbit antibody to c-terminal region of P2Y13 (P2RY13): whole serum at 1 : 300 dilution incubated overnight at room temperature (21C) and developed with DAB/Ni. Rabbit Purified Hu C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

LTB4R / BLTR antibody

Western blot analysis of Jurkat cells (Lanes 1 and 2: 84ug cell lysate) and IM-9 cells (Lane 3: 54ug and Lane 4: 94ug of cell lysate) with anti-BLT1 antibody (1:2000). Rabbit IgG Purified Bov, Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LTB4R / BLTR antibody

Western blot analysis of acute T-cell leukemia Jurkat (lanes 1 and 4), promyelocytic leukemia HL-60 (lanes 2 and 5) and acute monocytic leukemia THP-1 (lanes 3 and 6) human cell lysates: 1-3. Anti-Human BLT1 (extracellular) antibody, (1:200). 4-6. Anti-Human BLT1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

LTB4R / BLTR (C-term) antibody

Anti-Leukotriene B4 Receptor / BLT1 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Eq, Hu, Mky, Ms, Op, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

LTB4R / BLTR (3rd cytopl. dom.) antibody

Anti-Leukotriene B4 Receptor antibody IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bov, Eq, Hu, Mky, Ms, Op, Platypus, Rb, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

LTB4R / BLTR (1st Cytopl. Dom.) antibody

Anti-Leukotriene B4 Receptor antibody IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hst, Hu, Mky, Ms, Rb, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

LTB4R / BLTR (2nd Cytopl. Dom.) antibody

Anti-Leukotriene B4 Receptor antibody IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bov, Hu, Mky, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

LTB4R / BLTR antibody

Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN BLTR: AZIDE FREE (SM1844A). Mouse IgG2a 202/7B1 Azide Free Hu C, F
1 mg / €830.00
  Acris Antibodies GmbH

LTB4R / BLTR antibody

Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN BLTR:FITC (SM1844F). Mouse IgG2a 202/7B1 FITC Hu C, F
0.1 mg / €500.00
  Acris Antibodies GmbH

LTB4R / BLTR antibody

Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN BLTR (SM1844P/PS/PT). Mouse IgG2a 202/7B1 Purified Hu C, F
0.2 mg / €490.00
  Acris Antibodies GmbH

LTB4R / BLTR antibody

Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN BLTR (SM1844PS). Mouse IgG2a 202/7B1 Purified Hu C, F
0.1 mg / €300.00
  Acris Antibodies GmbH

LTB4R / BLTR antibody

Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN BLTR (SM1844P/PS/PT). Mouse IgG2a 202/7B1 Purified Hu C, F
25 µg / €180.00
  Acris Antibodies GmbH

LTB4R / BLTR antibody

Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN BLTR:RPE (SM1844R). Mouse IgG2a 202/7B1 PE Hu F
100 Tests / €480.00
  Acris Antibodies GmbH

LTB4R / BLTR antibody

Staining of Human peripheral blood granulocytes with Mouse Anti Human BLTR:RPE (SM1844R/RT) Mouse IgG2a 202/7B1 PE Hu F
25 Tests / €220.00
  Acris Antibodies GmbH

LTB4R / BLTR Control Peptide

LTB4R / BLTR
50 µg / €220.00
  Acris Antibodies GmbH

LTB4R / BLTR antibody

LTB4R / BLTR Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

LTB4R / BLTR (C-term) antibody

LTB4R / BLTR Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

LTB4R / BLTR antibody

Flow Cytometry: BLTR Antibody (202/7B1) [NB100-63310] - Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN BLTR:RPE Mouse IgG2a 202/7B1 PE Hu F, P
50 Tests / €300.00
  Novus Biologicals Inc.

LTB4R / BLTR antibody

Flow Cytometry: BLTR Antibody (202/7B1) [NB100-64831] - Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN BLTR Mouse IgG2a 202/7B1 Purified Hu C, F, P
0.1 mg / €400.00
  Novus Biologicals Inc.

LTB4R / BLTR antibody

Flow Cytometry: BLTR Antibody (202/7B1) [NB100-64832] - Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN BLTR:FITC. Mouse IgG2a 202/7B1 FITC Hu C, F, P
50 µg / €340.00
  Novus Biologicals Inc.

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