LTBR / TNFR3 antibody

Principal name

LTBR / TNFR3 antibody

Alternative names for LTBR / TNFR3 antibody

Tumor necrosis factor receptor 3, TNF-R3, Tumor necrosis factor C receptor, TNFCR, TNFRSF3, D12S370, Lymphotoxin-beta receptor, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor receptor type III, Tumor necrosis factor receptor 2-related protein

SwissProt ID

P36941 (Human), P50284 (Mouse)

Gene ID

4055 (LTBR), 17000 (Ltbr)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Goat, Rat, Mouse, Chicken

Available applications

Enzyme Immunoassay (E), Flow Cytometry (F), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Functional assay (FN), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Paraffin Sections (P)

Background of LTBR / TNFR3 antibody

Tumor necrosis factor-beta (TNF-beta), also known as lymphotoxin (LT or LT-a) and cytotoxic factor, is a 25 kDa glycoprotein that is tightly regulated by lymphocytes. TNF-beta and TNF-alpha share a 28% amino acid sequence identity, and as soluble forms, both can exist in solution as homotrimers, activate the same TNF receptors (TNFR1 and TNFR2) and elicit many of the same bioactivities. Unlike TNF-alpha, TNF-beta can also form heterotrimers with one or two molecules of the related membrane-bound lymphotoxin-beta (LT-beta). Reportedly, LT-alpha1/beta2, the predominant heterotrimer, binds and activates only the LT-beta receptor, LT-betaR. The other heterotrimer, LT-alpha2/beta1 binds and activates TNFR1 and TNFR2 but not LT-betaR. TNF-beta is expressed in activated T, B and NK cells and in certain transformed cells. Genes for TNF-beta, LT-beta and TNF-alpha are tightly linked near each other within the MHC. TNF-beta appears to play many of the same biological roles as TNF-alpha, but the membrane-bound form with LT-beta is critical for normal lymphoid organ development. Genetic polymorphisms in TNF-alpha and TNF-beta have been linked to certain pathological conditions, including myasthenia gravis. At the amino acid level, human and mouse TNF-beta are 74% homologous and human and mouse LT-beta are 80% homologous.

General readings

Cheung, T.C., et al. J. Immunol. 185(3):1949-1958(2010)
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Sanjo, H., et al. J. Biol. Chem. 285(22):17148-17155(2010)
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LTBR / TNFR3 antibody

Western blot analysis of extracts from HeLa cells and HepG2 cells, using LTBR antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LTBR / TNFR3 antibody

TA320416 antibody was tested by flow cytometric analysis of NIH/3T3 cells. Rat eBio3C8 (3C8) Purified Ms F
0.1 mg / €280.00
  OriGene Technologies, Inc.

LTBR / TNFR3 antibody

Western blot analysis of extracts of mouse liver, using LTBR antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

LTBR / TNFR3 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LTBR (RC204734, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LTBR. Mouse IgG1 OTI3G10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11b Low Endotoxin Ms F, FN
0.5 mg / €680.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11b Purified Ms F
0.25 mg / €510.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11b Purified Ms F
0.1 mg / €440.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11b Purified Ms F
25 µg / €190.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11b PE Ms F
100 Tests / €600.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11 Purified Ms E, FN, WB
0.1 mg / €490.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

Western blot (WB) analysis of LTβR antibody (Cat.-No.: AP20415PU-N) in extracts from HeLa cells. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

LTBR / TNFR3 (N-term) antibody

Western blot analysis of LTBR Antibody (N-term) Cat.-No AP52559PU-N in mouse brain tissue lysates (35ug/lane). This demonstrates the LTBR antibody detected the LTBR protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

Western Blot analysis of LTBR expression in transfected 293T cell line (H00004055-T02) by LTBR MaxPab polyclonal antibody.

Lane 1: LTBR transfected lysate(46.70 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

LTBR / TNFR3 antibody

Western Blot analysis of LTBR expression in transfected 293T cell line (H00004055-T03) by LTBR MaxPab polyclonal antibody.

Lane 1: LTBR transfected lysate(46.70 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

LTBR / TNFR3 antibody

Flow cytometry with LTBR monoclonal antibody, clone Carlos-1 ( Cat # MAB3721 ). HEK 293T cells ( 5 X 105 ) were mock transfected ( thin line ) or transfected with an expression plasmid enabling surface expression of the extracellular domain of human LTBR ( thick line ). Rat IgG1 Carlos-1 Hu F, IP
0.1 mg / €640.00
  Abnova Taiwan Corp.

LTBR / TNFR3 antibody

Immunofluorescence analysis of HeLa cells, using LTBR Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

LTBR / TNFR3 antibody

Immunofluorescence analysis of HeLa cells, using LTBR Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

LTBR / TNFR3 antibody

LTBR / TNFR3 Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

LTBR / TNFR3 antibody

Western blot analysis of LTBR expression in HeLa (A); HuT78 (B); K562 (C) whole cell lysates. Rabbit Aff - Purified Hu WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

LTBR / TNFR3 antibody

Western blot analysis of LTBR expression in HeLa (A); HuT78 (B); K562 (C) whole cell lysates. Rabbit Aff - Purified Hu WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

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