LTBR / TNFR3 antibody

Principal name

LTBR / TNFR3 antibody

Alternative names for LTBR / TNFR3 antibody

Tumor necrosis factor receptor 3, TNF-R3, Tumor necrosis factor C receptor, TNFCR, TNFRSF3, D12S370, Lymphotoxin-beta receptor, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor receptor type III, Tumor necrosis factor receptor 2-related protein

SwissProt ID

P36941 (Human), P50284 (Mouse)

Gene ID

4055 (LTBR), 17000 (Ltbr)

Available reactivities

Ms (Mouse), Hu (Human)

Available hosts

Rat, Mouse, Rabbit

Available applications

Functional assay (FN), Flow Cytometry (F), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), EPair for Elisa (EPair), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of LTBR / TNFR3 antibody

LTbetaR is a member of the tumor necrosis factor (TNF) family. This receptor can be activated by its functional ligands lymphotoxin-alpha1-beta2 (LT-alpha1beta2) and LIGHT and is critically involved in controlling bacterial infections. In Mycobacterium infection, its role is related to bactericidal granuloma formation in the spleen, macrophage differentiation and the maintenance of the appropriate Th1/Th2 cytokine balance. In CMV infection, LTbetaR signaling induces the expression of IFN-beta in infected fibroblasts, resulting in viral stasis. LTbetaR plays an important role in lymphoid organogenesis and tumor development. The receptor is expressed on fibroblasts and stromal cells and at low levels in some myeloid cell lines. In the adult animal, the LTbetaR seems to be necessary for maintaining the splenic architecture and aspects of Ig formation and B cell follicular structure. When the LT-alpha1beta2/LTbetaR pathway is disrupted by genetic deletion, mice completely lack Peyer's patches. Also, LTbetaR induces cell death in some adenocarcinoma tumor lines in the presence of IFNgamma.

General readings

Cheung, T.C., et al. J. Immunol. 185(3):1949-1958(2010)
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Sanjo, H., et al. J. Biol. Chem. 285(22):17148-17155(2010)
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LTBR / TNFR3 antibody

Western blot analysis of extracts from HeLa cells and HepG2 cells, using LTBR antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LTBR / TNFR3 antibody

TA320416 antibody was tested by flow cytometric analysis of NIH/3T3 cells. Rat eBio3C8 (3C8) Purified Ms F
0.1 mg / €280.00
  OriGene Technologies, Inc.

LTBR / TNFR3 antibody

Host: Rabbit; Target Name: LTBR; Sample Tissue: HepG2 Whole cell lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

LTBR / TNFR3 antibody

Western blot analysis of extracts of mouse liver, using LTBR antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

LTBR / TNFR3 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LTBR (RC204734, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LTBR. Mouse IgG1 OTI3G10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11b Low Endotoxin Ms F, FN
0.5 mg / €680.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11b Purified Ms F
0.25 mg / €510.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11b Purified Ms F
0.1 mg / €440.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11b Purified Ms F
25 µg / €190.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11b PE Ms F
100 Tests / €600.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

LTBR / TNFR3 Rat IgG2a 5G11 Purified Ms E, FN, WB
0.1 mg / €500.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

Western blot (WB) analysis of LTβR antibody (Cat.-No.: AP20415PU-N) in extracts from HeLa cells. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

LTBR / TNFR3 (N-term) antibody

Western blot analysis of LTBR Antibody (N-term) Cat.-No AP52559PU-N in mouse brain tissue lysates (35ug/lane). This demonstrates the LTBR antibody detected the LTBR protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

LTBR / TNFR3 antibody

Western Blot analysis of LTBR expression in transfected 293T cell line (H00004055-T02) by LTBR MaxPab polyclonal antibody.

Lane 1: LTBR transfected lysate(46.70 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

LTBR / TNFR3 antibody

Western Blot analysis of LTBR expression in transfected 293T cell line (H00004055-T03) by LTBR MaxPab polyclonal antibody.

Lane 1: LTBR transfected lysate(46.70 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

LTBR / TNFR3 antibody

Flow cytometry with LTBR monoclonal antibody, clone Carlos-1 ( Cat # MAB3721 ). HEK 293T cells ( 5 X 105 ) were mock transfected ( thin line ) or transfected with an expression plasmid enabling surface expression of the extracellular domain of human LTBR ( thick line ). Rat IgG1 Carlos-1 Hu F, IP
0.1 mg / €640.00
  Abnova Taiwan Corp.

LTBR / TNFR3 antibody

Immunofluorescence analysis of HeLa cells, using LTBR Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

LTBR / TNFR3 antibody

Immunofluorescence analysis of HeLa cells, using LTBR Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

LTBR / TNFR3 antibody

LTBR / TNFR3 Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

LTBR / TNFR3 antibody

Western blot analysis of LTBR expression in HeLa (A); HuT78 (B); K562 (C) whole cell lysates. Rabbit Aff - Purified Hu WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

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