Ly6G / GR1 Neutrophil Marker antibody

Principal name

Ly6G / GR1 Neutrophil Marker antibody

Alternative names for Ly6G / GR1 Neutrophil Marker antibody

Gr-1 Granulocyte marker

SwissProt ID

P35461 (Mouse)

Gene ID

546644 (Ly6g)

Ncbi ID

10090

Available reactivities

Ms (Mouse), Rt (Rat)

Available hosts

Rat, Rabbit

Available applications

Cytotoxicity Assay (CT), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Frozen Sections (C), Functional assay (FN), Enzyme Immunoassay (E), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Ly6G / GR1 Neutrophil Marker antibody

The Ly-6G/-6C locus encodes a family of Ly-6 proteins including Ly-6G and Ly-6C. Ly-6 antigens have a molecular weight between 15,000 and 18,000. Ly6G is together with Ly6c a component of the myeloid differentiation antigen Gr-1. Ly6G a GPI-anchored protein and is a good marker of peripheral neutrophils. Although predominantly presents on neutrophils, it is also expressed on a subset of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells. Ly6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon gamma, and may play a role in the development and maturation of lymphocytes. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T cell subsets. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. However, the physiological role of Ly6G alone remains still unclear.

General readings

1. Lopez, A et al; Differentiation antigens on mouse eosinophils and neutrophils identified by monoclonal antibodies, Brit J Haematology 1984, 57: 489
2. McLaren, D et al; Schistosoma mansoni: evidence that immunity in vaccinated and chronically infected CBA/Ca mice is sensitive to treatment with a monoclonal antibody
that depletes cutaneous effector cells. Parasite Immunol 1987, 9: 667
3. Folkard, S et al; Eosinophils are the major effector cells of immunity to microfilariae in a mouse model of onchocerciasis. Parasitology 1996, 112: 323
4. Van Lent, P et al; Monocytes/macrophages rather than PMN are involved in early cartilage degradation in cationic immune complex arthritits in mice. J Leukoc Biol 1997, 61: 267
5. Lubberts, E et al; Adenoviral vector-mediated overexpression of IL-4 in the knee joint
of mice with collagen-induced arthritis prevents cartilage destruction. J Immunol 1999, 163: 4546
6. Tacchini-Cottier, F et al; An immunomodulatory function for neutrophils during the induction of a CD4+ Th2 response in BALB/c mice infected with Leishmania major. J Immunol 2000, 165: 628
7. Nagendra, S et al; Absence of cross-reactivity between mouse Ly-6C and Ly-6G. Cytometry A 2004, 58: 195 1. de Vries B et al. Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils. J Immunol 170:3883-9 (2003). PubMed: 12646657

  1. Quick-Filters:
  2. Cited (1)

Items 1 to 20 of 21 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Ly6G / GR1 Neutrophil Marker antibody

Figure 1. Ly6G Immunohistochemistry staining paraffin sections of Mouse kidney and spleen tissues from LPS exposed animals. Rat IgG2 6D17 Purified Ms F, P
0.1 mg / €440.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Staining for Ly-6G/-6C of frozen section of mouse spleen Rat IgG2b NIMP-R14 Biotin Ms C, E, FN, P
50 µg / €280.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Staining for Ly-6G/-6C of frozen section of mouse spleen Rat IgG2b NIMP-R14 FITC Ms C, E, FN, P
0.1 mg / €390.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Staining for Ly-6G/-6C of frozen section of mouse spleen Rat IgG2b NIMP-R14 Purified Ms C, E, F, FN, P
0.1 mg / €340.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Staining for Ly-6G/-6C of frozen section of mouse spleen. Rat IgG2b NIMP-R14 PE Ms C, E, FN, P
100 Tests / €390.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Staining for Ly-6G/-6C of frozen section of mouse spleen. Rat IgG2b NIMP-R14 PE Ms C, E, FN, P
25 Tests / €220.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Cell Source: Bone Marrow Monocytes - Percentage of cells stained above control: 93.2% Rat IgG2b RB6-8C5 Ascites Ms CT, F, WB
0.5 ml / €500.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Cell Source: Bone Marrow Monocytes. Percentage of cells stained above control: 95.3% Rat IgG2b RB6-8C5 Biotin Ms C, F, P, WB
0.1 mg / €230.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Cell Source: Bone Marrow Monocytes. Percentage of cells stained above control: 95.3% Rat IgG2b RB6-8C5 Biotin Ms C, F, P, WB
0.3 mg / €400.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Ly6G / GR1 Neutrophil Marker Rat IgG2b RB6-8C5 FITC Ms F, WB
0.1 mg / €230.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Ly6G / GR1 Neutrophil Marker Rat IgG2b RB6-8C5 FITC Ms F, WB
0.3 mg / €400.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Ly6G / GR1 Neutrophil Marker Rat IgG2b RB6-8C5 Purified Ms C, CT, F, P, WB
0.25 mg / €290.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Ly6G / GR1 Neutrophil Marker Rat IgG2b RB6-8C5 Purified Ms C, F, IP, WB
25 µg / €170.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Ly6G / GR1 Neutrophil Marker Rat IgG2b RB6-8C5 PE Ms F
100 Tests / €300.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

Ly6G / GR1 Neutrophil Marker Rat IgG2b RB6-8C5 PE Ms F
25 Tests / €210.00
  Acris Antibodies GmbH

Ly6G / GR1 Neutrophil Marker antibody

BALB/c bone marrow cells were stained with either rat IgG2b-FITC ( as an isotype control ) or Ly6g monoclonal antibody-FITC. Large cells were then gated and analyzed on a FACScanTM flow cytometer ( BDIS, San Jose, CA ). Rat IgG2b RB6-8C5 Ms C, F, IP, WB
0.5 mg / €400.00
  Abnova Taiwan Corp.

Ly6G / GR1 Neutrophil Marker antibody

Ly6G / GR1 Neutrophil Marker Rat IgG2b RB6-8C5 PE Ms F
100 Tests / €300.00
  Novus Biologicals Inc.

Ly6G / GR1 Neutrophil Marker antibody

Immunohistochemistry-Frozen: Ly-6G6C Neutrophil Marker Antibody (NIMP-R14) [NB600-1387] - Staining for Ly-6G/-6C of frozen section of mouse spleen Rat IgG2b NIMP-R14 Purified Ms C, E, F, FN, P
50 µg / €380.00
  Novus Biologicals Inc.

Ly6G / GR1 Neutrophil Marker antibody

Ly6G / GR1 Neutrophil Marker Rat IgG2 AP-MAB0866 Purified Ms F, IP, P
0.5 mg / €380.00
  Novus Biologicals Inc.

Ly6G / GR1 Neutrophil Marker antibody

Flow cytometry: Ly-6G Antibody (RB6-8C5) [NBP1-28167] - 1 ug/1^6 BALB/c bone marrow cells were stained with either rat IgG2b-FITC (as an isotype control) or rat anti-mouse Ly-6G-FITC. Large cells were then gated and analyzed on a flow cytometer Rat IgG2b RB6-8C5 FITC Ms C, F, IP, P, WB
0.25 mg / €230.00
  Novus Biologicals Inc.

Items 1 to 20 of 21 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn