LY6K antibody

Principal name

LY6K antibody

Alternative names for LY6K antibody

CO16, Ly-6K, Lymphocyte antigen 6K

SwissProt ID

Q17RY6 (Human), Q9CWP4 (Mouse)

Gene ID

54742 (LY6K)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of LY6K antibody

LY6K Antibody: The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mR was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siR reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.

General readings

de Nooij-van Dalen AG, van Dongen GA, Smeets SJ, et al. Characterization of the human Ly-6 antigens, the newly annotated member Ly-6K included, as molecular markers for head-and-neck squamous cell carcinoma. Int. J. Cancer 2003; 103:768-74.
Lee JW, Lee YS, Yoo KH, et al. LY-6K gene: a novel molecular marker for human breast cancer. Oncol. Rep. 2006; 16:1211-4.
Yoshitake H, Tsukamoto H, Maruyama-Fukushima M, et al. TEX101, a germ cell-marker glycoprotein, is associated with lymphocyte antigen 6 complex locus K within the mouse testis. Biochem. Biophys. Res. Commun. 2008; 372:277-82.
Maruyama M, Yoshitake H, Tsukamoto H, et al. Molecular expression of Ly6k, a putative glycosylphosphatidyl-inositol-anchored membrane protein on the mouse testicular germ cells. Biochem. Biophys. Res. Commun. 2010; 402:75-81.

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LY6K (N-term) antibody

Western blot analysis of LY6K in HeLa cell lysate with LY6K antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LY6K (N-term) Control Peptide

LY6K
50 µg / €160.00
  Acris Antibodies GmbH

LY6K antibody

LY6K Rabbit Hu E, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

LY6K antibody

Immunohistochemistry-Paraffin: Ly-6K Antibody [NBP1-84340] - Immunohistochemical staining of human small intestine shows positivity of microvilli in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

LY6K

LY6K Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

LY6K

LY6K Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

LY6K

LY6K Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

LY6K overexpression lysate

LY6K overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

8 Item(s)

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