LYL1 antibody

Principal name

LYL1 antibody

Alternative names for LYL1 antibody

Protein lyl-1, BHLHA18, Class A basic helix-loop-helix protein 18, Lymphoblastic leukemia-derived sequence 1

SwissProt ID

P12980 (Human), P27792 (Mouse), Q66HH3 (Rat)

Gene ID

4066 (LYL1), 17095 (Lyl1), 304663

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rat, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of LYL1 antibody

The Lyl1 gene encodes a basic helix–loop–helix transcription factor involved in T-cell acute lymphoblastic leukemia. The expression of Lyl1 is at higher levels in the majority of cases of acute myeloblastic leukemia (AML) or myelodysplastic syndrome when compared to normal bone marrow. Lyl1 is highly expressed in most AML cell lines.Lyl-1, TAL1 and TAL2 are part of a family of basic helix-loop-helix (bHLH) proteins implicated in T cell acute leukemia. TAL1, also designated SCL, is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. TAL2 is a protein involved in T cell acute lymphoblastic leukemia through a chromosomal translocation involving TAL2 and T cell receptor ∫ chain genes. TAL2 includes a helix-loop-helix protein dimerization and DNA-binding domain that is homologous to TAL1 and Lyl-1 proto-oncogenes. Lyl-1 (lymphoblastic leukemia-derived sequence 1) is a nuclear protein. Endogenous Lyl-1 exists in complex with E2å proteins. Lyl-1 and E2å protein can form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells. Lyl-1 is involved in a chromosomal aberration which causes a form of T cell acute lymphoblastic leukemia (T-ALL).

General readings

Meier N, Krpic S, Rodriguez P, Strouboulis J, Monti M, Krijgsveld J, Gering M, Patient R, Hostert A, Grosveld F. 2006. Novel binding partners of Ldb1 are required for haematopoietic development. Development 133:4913-23.

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LYL1 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Lyl-1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

LYL1 antibody

WB Suggested Anti-LYL1 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysateLYL1 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

LYL1 antibody

Host: Rabbit; Target Name: Lyl1; Sample Tissue: Rat Spleen lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

LYL1 antibody

LYL1 Rat IgG2a KT43 Aff - Purified Ms IP, WB
1 mg / €910.00
  Acris Antibodies GmbH

LYL1 antibody

LYL1 Rat IgG2a KT43 Aff - Purified Ms IP, WB
0.2 mg / €450.00
  Acris Antibodies GmbH

LYL1 antibody

LYL1 Rat IgG2a KT43 Aff - Purified Ms IP, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

LYL1 antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

LYL1 antibody

Western Blot analysis of LYL1 expression in transfected 293T cell line (H00004066-T01) by LYL1 MaxPab polyclonal antibody.

Lane 1: LYL1 transfected lysate(30.8 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

LYL1 antibody

Western Blot analysis of LYL1 expression in transfected 293T cell line (H00004066-T01) by LYL1 MaxPab polyclonal antibody.

Lane 1: LYL1 transfected lysate(30.8 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

LYL1 antibody

LYL1 Rat IgG2a KT43 Ms IP, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

LYL1 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Lyl-1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €205.00
  Assay Biotech

LYL1 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Lyl-1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €310.00
  Assay Biotech

LYL1 antibody

Human HepG2; WB Suggested Anti-LYL1 Antibody Titration: 0.2-1 ug/ml. Positive Control: HepG2 cell lysate; LYL1 antibody - C-terminal region (ARP31393_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

LYL1 antibody

Human 721_B; WB Suggested Anti-LYL1 Antibody Titration: 0.2-1 ug/ml. Positive Control: 721_B cell lysate. LYL1 is supported by BioGPS gene expression data to be expressed in 721_B.; LYL1 antibody - N-terminal region (P100710_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

LYL1 antibody

LYL1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €360.00
  Novus Biologicals Inc.

LYL1 antibody

LYL1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
50 µg / €290.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

LYL1 Lysate(Denatured)

LYL1 Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

LYL1 overexpression lysate

LYL1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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