LYVE-1 antibody

Principal name

LYVE-1 antibody

Alternative names for LYVE-1 antibody

LYVE1, CRSBP-1, CRSBP1, HAR, XLKD1, Lymphatic vessel endothelial hyaluronic acid receptor 1, Cell surface retention sequence-binding protein 1, Hyaluronic acid receptor, Extracellular link domain-containing protein 1

SwissProt ID

Q6UC88 (Bovin), Q8BHC0 (Mouse), Q9Y5Y7 (Human)

Gene ID

10894 (LYVE1), 114332 (Lyve1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Rat, Goat

Available applications

Flow Cytometry (F), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of LYVE-1 antibody

LYVE1 (lymphatic vessel endothelial hyaluron receptor-1) is the lymphatic vessel endothelial hyaluronic acid receptor located in lymph nodes and in the lumil/ablumil surfaces of lymphatic vessels. It is one of the most specific and widely used mammalian lymphatic endothelial markers. LYVE-1 exists as disulfide-linked homodimer, can interact with PDGFB/IGFBP3 and also forms transient terry complex with PDGFB and PDGFRB in trans-Golgi network (TGN). LYVE1 is a single-pass type I membrane protein localized in plasma membrane and in vesicles near extranuclear membranes which represents TGN and endosomes or pre-lysosomeal compartments. LYVE1 undergoes ligand-dependent interlization and recycling at the cell surface, and executes ligand-specific transporter trafficking between intracellular organelles/TGN and plasma membrane. LYVE1 plays a key role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding. LYVE1 behaves as hyaluron transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. LYVE-1 is very efficient in the passage of lymphocytes as well as the tumor cells into the lymphatics.

General readings

Koukourakis MI. et al. (2006) J. Clin. Pathol. 58, 202-206.
Chen L. et al. (2005) Invest. Ophthalmol Vis. Sci. 46, 4536-4540.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

LYVE-1 antibody

DP3500 LYVE-1 antibody staining of Human Spleen Paraffin section.
The experiment was performed by Prof. Dr. Birte Steiniger, Institute of Anatomy and Cell Biology Robert-Koch-Str. 8, D-35037 Marburg, Germany. Rabbit Purified Hu C, E, F, P, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

LYVE-1 antibody

LYVE-1 antibody staining of Human Intestine (border area of a Colon Carcinoma).
The experiment has been performed by Dr. Karsten Debel, DCS, Hamburg, Germany. Rabbit Aff - Purified Hu C, E, F, P, WB
50 µg / €280.00
  Acris Antibodies GmbH

LYVE-1 antibody

Figure 4. LYVE-1 and CD31 staining on frozen sections (5μm) of the Mouse prostate.The experiments were performed by Scott Gerber & Edith Lord, PhD, University of Rochester, USA. Rabbit Purified Ms C, E, F, ICC/IF, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

LYVE-1 antibody

Paraffin Section of Mouse Intestine stained with LYVE-1 Antibody Cat.-No DP3513P. You see the Staining (red) of lymphatic endothelial cells of the intestine. Rabbit IgG Aff - Purified Ms, Rt C, E, F, ICC/IF, P, WB
50 µg / €280.00
  Acris Antibodies GmbH

LYVE-1 antibody

DP3500 LYVE-1 antibody staining of Human Spleen Paraffin section.
The experiment was performed by Prof. Dr. Birte Steiniger, Institute of Anatomy and Cell Biology Robert-Koch-Str. 8, D-35037 Marburg, Germany. Rabbit Purified Hu C, E, F, P, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

LYVE-1 antibody

Figure 4. LYVE-1 and CD31 staining on frozen sections (5μm) of the Mouse prostate.The experiments were performed by Scott Gerber & Edith Lord, PhD, University of Rochester, USA. Rabbit Purified Ms C, E, F, ICC/IF, WB

Regular Price: 0.1 mg / €270.00

Special Price: 0.1 mg / €202.50

  Acris Antibodies GmbH

LYVE-1 antibody

  Rabbit Polyclonal LYVE-1 Antibody  
Western Blot: LYVE1 Antibody [TA336490] - Analysis of LYVE1 in human lymph node lysate. Rabbit Purified Hu, Ms, Rt C, F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LYVE-1 antibody

  Rabbit Polyclonal Antibody against LYVE1  
Detection of LYVE-1 in recombinant human protein, ECL detection overnight Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LYVE-1 antibody

  Rat Anti-Mouse Lyve-1 Purified (25 ug)  
Immunohistochemistry of cryosections of mouse intestine at 2.5 ug/ml of anti-mouse LYVE-1 antibody followed by Anti-Rat IgG Rhodamine (right). Phase image of same field (left). Rat ALY7 Purified Ms F, P
25 µg / €120.00
  OriGene Technologies, Inc.

LYVE-1 antibody

  Anti-LYVE1 rabbit polyclonal antibody  
Predicted band size: 35kDa. Positive control: A549 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LYVE-1 antibody

  Anti-LYVE1 rabbit polyclonal antibody  
Predicted band size: 35 kDa . Positive control: Mouse liver tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 50 ug Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

LYVE-1 antibody

  Rabbit Polyclonal Anti-LYVE1 Antibody  
WB Suggested Anti-LYVE1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

LYVE-1 antibody

  Rabbit Polyclonal Anti-LYVE1 Antibody  
Western blot analysis of LYVE1 expression in MCF7 whole cell lysates, the lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LYVE-1 antibody

  Goat Polyclonal Anti-LYVE1 Antibody  
TA348956 (2 ug/ml) staining of Human Cerebellum (A) and Liver (B) lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

LYVE-1 (1-228) antibody

Immunohistochemical detection of Mouse LYVE-1 on paraffin embedded section of lymhatic vessel in Mouse intestine with AM26529AF-N.These paraffin sections were kindly provided by Dr. Tohru Morisada, M.D. Ph.D (The department of Cell Differentiation, The Sakaguchi Laboratory, Department of Obstetrics and Gynecology, School of Medicine, Keiro University, Tokyo) Rat IgG1 ALY7 Azide Free Ms F, P
0.1 mg / €370.00
  Acris Antibodies GmbH

LYVE-1 (N-term) antibody

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

LYVE-1 (C-term) antibody

Figure 2. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

LYVE-1 (271-275) antibody

Western blot analysis of extracts from MCF cells using Lymphatic vessel endothelial hyaluronic acid receptor 1 Antibody AP26047PU-N and the same antibody preincubated with blocking peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €320.00
  Acris Antibodies GmbH

LYVE-1 (271-275) antibody

Western blot analysis of extracts from MCF cells using Lymphatic vessel endothelial hyaluronic acid receptor 1 Antibody AP26047PU-N and the same antibody preincubated with blocking peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €240.00
  Acris Antibodies GmbH

LYVE-1 antibody

FACS analysis with Biotin conjugated DP3500B LYVE-1 antibody using HDMVECs Rabbit Biotin Hu F
50 µg / €320.00
  Acris Antibodies GmbH

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