MACROD1 / LRP16 antibody

Principal name

MACROD1 / LRP16 antibody

Alternative names for MACROD1 / LRP16 antibody

MACRO domain-containing protein 1, Protein LRP16, [Protein ADP-ribosylglutamate] hydrolase, O-acetyl-ADP-ribose deacetylase MACROD1

Gene ID

28992 (MACROD1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Ms (Mouse), Por (Porcine), Rt (Rat)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of MACROD1 / LRP16 antibody

MACROD1 deacetylates O-acetyl-ADP ribose, a sigling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. It plays a role in estrogen sigling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen and may play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. It could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 sigl transduction and could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. MACROD1 enhances ESR1-mediated transcription activity.

3 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MACROD1 / LRP16 antibody

Host: Rabbit; Target Name: MACROD1; Sample Tissue: Fetal Brain lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

MACROD1 / LRP16 antibody

Immunohistochemistry-Paraffin: MACROD1 Antibody [NBP1-93535] Immunohistochemical staining of human colon shows strong cytoplasmic positivity with granular pattern in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

MACROD1 overexpression lysate

MACROD1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

3 Item(s)

per page
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