MAFK antibody

Principal name

MAFK antibody

Alternative names for MAFK antibody

Transcription factor MafK, v-maf musculoaponeurotic fibrosarcoma oncogene homolog K

SwissProt ID

O60675 (Human), Q61827 (Mouse), Q90596 (Chick)

Gene ID

7975 (MAFK), 17135 (Mafk)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Xen (Xenopus), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Sh (Sheep)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ChIP assay (ChIP), Immunoprecipitation (IP)

Background of MAFK antibody

The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors. Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins. Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements. Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers. Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library. Human MAFF encodes a 164 amino acids proten. Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Interestingly, these three proteins regulate the stress response via different mechanisms.

General readings

Iwata T, et al. (1998) Cytogenet Cell Genet 82 (1–2): 88–90.Du MJ, et al. (2008) Int J Biochem Cell Biol. 40(8):1481-93.

12 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MAFK antibody

WB Suggested Anti-MAFK Antibody Titration: 2.5 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MAFK antibody

The cell lysates of Jurkat (30ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human MAFK antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a AT2F7 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

MAFK antibody

The cell lysates of Jurkat (30ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human MAFK antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a AT2F7 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

MAFK (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MAFK (N-term) antibody

Mouse Liver; WB Suggested Anti-Mafk Antibody. . Titration: 1.0 ug/ml. . Positive Control: Mouse Liver; Mafk antibody - N-terminal region (ARP47558_P050) in Mouse Liver cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

MAFK antibody

Human Jurkat; WB Suggested Anti-MAFK Antibody Titration: 2.5ug/ml. Positive Control: Jurkat cell lysate; MAFK antibody - N-terminal region (ARP47559_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

MAFK antibody

MAFK Rabbit Aff - Purified Hu, Ms WB
50 µg / €440.00
  Novus Biologicals Inc.

MAFK antibody

MAFK Rabbit Purified Bov, Can, Chk, Hu, Ms, Rt, Xen, Ze WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MAFK (1-156, His-tag)

MAFK Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €940.00
  Acris Antibodies GmbH

MAFK (1-156, His-tag)

MAFK Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

MAFK

MAFK Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

MAFK

MAFK Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

12 Item(s)

per page
  • LinkedIn