MALT1 antibody

Principal name

MALT1 antibody

Alternative names for MALT1 antibody

Mucosa-associated lymphoid tissue lymphoma translocation protein 1, MLT, Paracaspase, MALT lymphoma-associated translocation

SwissProt ID

Q2TBA3 (Mouse), Q9UDY8 (Human)

Gene ID

10892 (MALT1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), ELISA (detection) (E(detection))

Background of MALT1 antibody

MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB. MALT1 is thought to play an importantrole in NF-kappaB signaling by enchancing NF-kappaB activation through interaction with Bcl10 (Ho et al., 2005). Interaction between MALT1 and Bcl10 mediates IKK activation in vitro through facilitatiing the ubiquitination of NEMO by the ubiquitin-conjugating enzyme UBC13. Four recurrent chromosomal translocations have been described in non-Hodgkin B-cell lymphoma of the mucosa-associated lymphoid issue (MALT) type. Two of them,t(14;18)(q32;q21) and t(11;18)(q21;q21), are found in 30% to 50% of extranodal MALT lymphomas. The first translocation juxtaposes the MALT1 gene to the IgH promoter region, resulting in the deregulation of MALT1 expression, whereas the second translocation generates a fusion between MALT1 and the inhibitor of apoptosis gene API2 (cIAP2/HIAP1). The other two much rarer translocations, t(1;14)(p22;q32)and t(1;2)(p22;p12), target Bcl10 gene on the short arm of chromosome 1. Translocations involving Bcl10 and MALT1 may lead to elevated NF-kappaB activity in MALT B-cell lymphoma. Two alternatively spliced transcript variants encoding different isoforms (a and b) have been described for the MALT1 gene. Human MALT1 isoform a is an amino acid protein of 824 amino acids, and human MALT1 isoform b is an amino acid protein of 813 amino acids.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MALT1 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-MALT1 Rabbit Polyclonal antibody. (TA590229) Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MALT1 antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-MALT1 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA807311)(1:150) Mouse IgG2a OTI3A2 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MALT1 (701-808) antibody

Formalin-Fixed, Paraffin-Embedded Human tonsil stained with MALT1 Antibody Cat.-No AM32840PU (Clone MT1/410). Mouse IgG1 MT1/410 Purified Hu C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

MALT1 (701-808) antibody

Formalin-Fixed, Paraffin-Embedded Human tonsil stained with MALT1 Antibody Cat.-No AM32840PU (Clone MT1/410). Mouse IgG1 MT1/410 Purified Hu C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

MALT1 (701-808) antibody

Formalin-Fixed, Paraffin-Embedded Human tonsil stained with MALT1 Antibody Cat.-No AM32840PU (Clone MT1/410). Mouse IgG1 MT1/410 Purified Hu C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

MALT1 antibody

Formalin-Fixed, Paraffin-Embedded Human tonsil stained with MALT1 Antibody Cat.-No AM50100PU (Clone SPM578). Mouse IgG1 SPM578 Purified Hu C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

MALT1 antibody

Formalin-Fixed, Paraffin-Embedded Human tonsil stained with MALT1 Antibody Cat.-No AM50100PU (Clone SPM578). Mouse IgG1 SPM578 Purified Hu C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

MALT1 antibody

Formalin-Fixed, Paraffin-Embedded Human tonsil stained with MALT1 Antibody Cat.-No AM50100PU (Clone SPM578). Mouse IgG1 SPM578 Purified Hu C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

MALT1 antibody

Human lymphoma stained with anti-MALT-1 antibody Rabbit IgG Aff - Purified Hu P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

MALT1 antibody

Human lymphoma stained with anti-MALT-1 antibody Rabbit IgG Aff - Purified Hu P, WB
1 ml / €520.00
  Acris Antibodies GmbH

MALT1 antibody

Human lymphoma stained with anti-MALT-1 antibody Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €190.00
  Acris Antibodies GmbH

MALT1 antibody

Sample (30 ug of whole cell lysate). A: HeLa. B: Hep G2 . 10% SDS PAGE. TA308644 diluted at 1:10000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MALT1 antibody

Immunohistochemistry on formalin-fixed paraffin embedded human tonsil tissue with citrate buffer antigen retrieval, using 10 ug/ml of Anti-Human MALT1 Purified (right) or Mouse IgG1 kappa Isotype Control Purified antibody (left) followed by Anti-Mouse Ig Biotin and DAB visualization. Nuclei are counterstained with hematoxylin. Mouse 50 Purified Hu P, WB
25 µg / €120.00
  OriGene Technologies, Inc.

MALT1 antibody

Predicted band size: 92 kDa . Positive control: Jurkat and K562 cell, bone marrow tissue lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lane1: Jurkat cell lysate Lane2: K562 cell lysate Lane3: Bone marrow tissue lysate Lysates: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MALT1 antibody

Western blot analysis of MALT1 in EL4 cell lysate with MALT1 antibody at (A) 1 and (2) ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MALT1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MALT1 (RC214639, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MALT1.(1:500) Mouse IgG2a OTI6C11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MALT1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MALT1 (RC214639, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MALT1.(1:2000) Mouse IgG1 OTI6D2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MALT1 antibody

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-MALT1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA807326)(1:150) Mouse IgG1 OTI4C3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MALT1 antibody

Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-MALT1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA807328)(1:150) Mouse IgG1 OTI3E10 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MALT1 (43-57) antibody

Colon, lymphoid follicle: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

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