MAN1B1 antibody

Principal name

MAN1B1 antibody

Alternative names for MAN1B1 antibody

ER alpha-1,2-mannosidase, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, Mannosidase alpha class 1B member 1, Man9GlcNAc2-specific-processing alpha-mannosidase

SwissProt ID

Q9UKM7 (Human)

Gene ID

11253 (MAN1B1)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of MAN1B1 antibody

ERManI, also known as endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase or MAN1B1, is a putative ER resident mannosidase that plays a rate-limiting role in generating a sigl that targets misfolded N-linked glycoproteins for ER-associated degradation (ERAD). ERManI codes for an enzyme that converts Man9Glcc to Man8Glcc isomer B during N-glycan biosynthesis. It also facilitates the trimming of Man5-6Glcc2 in the endoplasmic reticulum associated degradation pathway. Multiple transcript variants of ERManI can result from altertive splicing, and a related pseudogene can be found on chromosome 11. Research has found that mutations on the ERManI gene can result in autosomal-recessive intellectual disabilities and developmental delays (PMID: 21763484). ERManI is predomitely localized to the Golgi and endoplasmic reticulum.

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MAN1B1 antibody

  Rabbit polyclonal antibody to MAN1B1 (mannosidase, alpha, class 1B, member 1)  
Sample (30 ug of whole cell lysate). A: Hela. 7.5% SDS PAGE. MAN1B1 antibody. TA307927 diluted at 1:1000. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MAN1B1 antibody

  Rabbit polyclonal anti-MAN1B1 antibody  
Western blot analysis of extracts from 3T3 cells, using MAN1B1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MAN1B1 antibody

  Mouse Monoclonal ERManI Antibody (3C2)  
Western Blot: ERManI Antibody (3C2) [TA336898] - Western blot analysis of ERManI expression in 1) NTERA-2 and 2) A-431 whole cell lysates. Mouse IgG1 3C2 Purified Hu, Ms C, E, ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MAN1B1 antibody

  Rabbit Polyclonal Anti-MAN1B1 Antibody  
Western blot analysis on 3T3 cell lysate using MAN1B1 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

MAN1B1 - human gene knockout kit via CRISPR

MAN1B1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MAN1B1 - human gene knockout kit via CRISPR

MAN1B1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAN1B1 - human gene knockout kit via CRISPR

MAN1B1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAN1B1 - human gene knockout kit via CRISPR

MAN1B1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MAN1B1

  Purified recombinant protein of Human mannosidase, alpha, class 1B, member 1 (MAN1B1)  
MAN1B1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

MAN1B1 overexpression lysate

MAN1B1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MAN1B1 (mGFP-tagged) - Human mannosidase, alpha, class 1B, member 1 (MAN1B1), 200 uL, >10^7 TU/mL

Lenti ORF particles, MAN1B1 (mGFP-tagged) - Human mannosidase, alpha, class 1B, member 1 (MAN1B1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, MAN1B1 (Myc-DDK tagged) - Human mannosidase, alpha, class 1B, member 1 (MAN1B1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, MAN1B1 (Myc-DDK tagged) - Human mannosidase, alpha, class 1B, member 1 (MAN1B1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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