MAP Kinase Phosphatase X antibody

Principal name

MAP Kinase Phosphatase X antibody

Alternative names for MAP Kinase Phosphatase X antibody

DUSP22, JSP1, MKPX, Dual specificity protein phosphatase 22, JNK-stimulatory phosphatase-1, Mitogen-activated protein kinase phosphatase x

SwissProt ID

Q99N11 (Mouse), Q9NRW4 (Human)

Gene ID

56940 (DUSP22), 105352 (Dusp22)

Available reactivities

Hu (Human), Ms (Mouse), Chk (Chicken), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P)

Background of MAP Kinase Phosphatase X antibody

MKPX, also known as JSP-1 for Jnk stimulatory phosphatase-1, belongs to the LMW-DSP subfamily of phosphatases. MKPX has been shown to have the capacity to activate the c-Jun N-terminal kinase (Jnk) signaling pathway. The activation of Jnk has been implicated in a number of important physiological processes, including embryonic morphogenesis, cell survival and apoptosis. At least two mRNA transcripts have been reported. Jnk signaling has been linked to human disease conditions, such as tumor development, cardiac hypertrophy, ischemia/reperfusion injury, diabetes, hyperglycemia-induced apoptosis, and several neurodegenerative disorders.
MKPX has been shown to be widely expressed with highest expression in heart, kidney, liver, lung, pancreas and placenta. ESTs have been isolated from a diverse set of human tissues libraries, especially blood and breast.
Caution: The acronym MKPX also has been used to describe Dual specificity protein phosphatase 7 (rat).

General readings

Shen Y., et al. (2001) Proc. Natl. Acad. Sci. U.S.A. 98:13613-13618Schwertassek U., et al. (2010) FEBS J. 277:2463-2473

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MAP Kinase Phosphatase X antibody

  Rabbit polyclonal anti-DUSP22 antibody  
Western blot analysis of extracts from Jurkat cells and RAW264.7 cells, using DUSP22 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MAP Kinase Phosphatase X (N-term) antibody

  Rabbit Polyclonal Anti-DUSP22 Antibody (N-Terminus)  
MAP Kinase Phosphatase X Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

MAP Kinase Phosphatase X antibody

  Rabbit Polyclonal Anti-DUSP22 Antibody (Internal)  
MAP Kinase Phosphatase X Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

MAP Kinase Phosphatase X antibody

  Rabbit Polyclonal Anti-DUSP22 Antibody (Internal)  
Anti-DUSP22 / JSP 1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Chk, Hu, Ms, Rt
50 µg / €400.00
  OriGene Technologies, Inc.

MAP Kinase Phosphatase X antibody

  Rabbit Polyclonal Anti-DUSP22 Antibody - N-terminal region  
Host: Rabbit; Target Name: DUSP22; Sample Tissue: Thyroid Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MAP Kinase Phosphatase X antibody

  Rabbit Polyclonal Anti-DUSP22 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (DUSP22 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

MAP Kinase Phosphatase X antibody

Western blot analysis of extracts from RAW264.7/Jurkat cells, using DUSP22 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

MAP Kinase Phosphatase X antibody

Western blot analysis of extracts from RAW264.7/Jurkat cells, using DUSP22 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

DUSP22 - human gene knockout kit via CRISPR

DUSP22 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DUSP22 - human gene knockout kit via CRISPR

DUSP22 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DUSP22 - human gene knockout kit via CRISPR

DUSP22 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DUSP22 - human gene knockout kit via CRISPR

DUSP22 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dusp22 - mouse gene knockout kit via CRISPR

Dusp22 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MAP Kinase Phosphatase X (full length, N-term HIS tag)

  Recombinant protein of human dual specificity phosphatase 22 (DUSP22), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
MAP Kinase Phosphatase X Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

MAP Kinase Phosphatase X (1-184, His-tag)

MAP Kinase Phosphatase X Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €940.00
  Acris Antibodies GmbH

MAP Kinase Phosphatase X (1-184, His-tag)

MAP Kinase Phosphatase X Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

DUSP22 overexpression lysate

DUSP22 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DUSP22 (mGFP-tagged) - Human dual specificity phosphatase 22 (DUSP22), 200 uL, >10^7 TU/mL

Lenti ORF particles, DUSP22 (mGFP-tagged) - Human dual specificity phosphatase 22 (DUSP22), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, DUSP22 (Myc-DDK tagged) - Human dual specificity phosphatase 22 (DUSP22) , 200 uL, >10^7 TU/mL

Lenti ORF particles, DUSP22 (Myc-DDK tagged) - Human dual specificity phosphatase 22 (DUSP22) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Dusp22 (GFP-tagged) - Mouse dual specificity phosphatase 22 (Dusp22), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Dusp22 (GFP-tagged) - Mouse dual specificity phosphatase 22 (Dusp22), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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